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Catapres-TTS (Clonidine Hydrochloride Transdermal) - Summary

 



CATAPRES-TTS SUMMARY

CATAPRES-TTS® (clonidine) is a transdermal system providing continuous systemic delivery of clonidine for 7 days at an approximately constant rate. Clonidine is a centrally acting alpha-agonist hypotensive agent.

CATAPRES-TTS (clonidine) is indicated in the treatment of hypertension. It may be employed alone or concomitantly with other antihypertensive agents.


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NEWS HIGHLIGHTS

Media Articles Related to Catapres-TTS (Clonidine Transdermal)

clonidine, Catapres, Catapres-TTS
Source: MedicineNet Drug Abuse Specialty [2009.10.08]
Title: clonidine, Catapres, Catapres-TTS
Category: Medications
Created: 5/11/1998
Last Editorial Review: 10/8/2009

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Published Studies Related to Catapres-TTS (Clonidine Transdermal)

[Efficacy of clonidine transdermal patch for treatment of Tourette's syndrome in children] [2009.07]
OBJECTIVE: Children with Tourette's syndrome (TS) have a poor treatment compliance due to side effects and inconvenient administration of oral drugs. This study explored the efficacy and safety of clonidine transdermal patch for treating TS in children... CONCLUSIONS: Clonidine transdermal patch is effective for the treatment of TS in children and its side effects are mild and rare.

Randomized double-blind multicentre placebo-controlled clinical trial of the clonidine adhesive patch for the treatment of tic disorders. [2008.09]
CONCLUSIONS: The clonidine adhesive patch is effective and safe for tic disorders.

Clonidine for the treatment of supine hypertension and pressure natriuresis in autonomic failure. [2006.03]
Patients with autonomic failure are disabled by orthostatic hypotension, which can be worsened by the nighttime pressure natriuresis induced by associated supine hypertension... These results are consistent with residual sympathetic tone contributing to supine hypertension in autonomic failure, which can be targeted with clonidine to decrease BP and nocturnal natriuresis.

Opioid detoxification with buprenorphine, clonidine, or methadone in hospitalized heroin-dependent patients with HIV infection. [2003.04.01]
With the growing role of intravenous drug use in the transmission of HIV infection, HIV-infected patients frequently present with comorbid opioid dependence. Yet, few empirical evaluations of the efficacy and consequences of opioid detoxification medications in medically ill HIV-infected patients have been reported...

Transdermal clonidine: does it affect pain after abdominal hysterectomy? [2003]
Clonidine has analgesic properties.Clonidine had a weak opioid sparing effect 24 h post-operatively, but did not affect pain in long term.

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Clinical Trials Related to Catapres-TTS (Clonidine Transdermal)

Clonidine Versus Midazolam for Premedication [Completed]
alpha2-agonists like clonidine offer several useful effects that make these drugs an interesting alternative to benzodiazepines for pharmacological premedication. We therefore sought to determine the effect of pre-anesthetic medication with clonidine vs. midazolam in a randomized, double-blind, placebo controlled study. Effects of pre-anesthetic medication were assessed on (1) bispectral index (BIS),(2) sedation score and visual analog scales for anxiety and pain, (3) neuropsychologic tests to assess cognitive function and (4) circulating stress hormones.

Clonidine as Adjunct Therapy for the Treatment of Neonatal Abstinence Syndrome [Completed]
To test the hypothesis that the combination of the tincture of opium (DTO) and clonidine will be more effective in treating infants with neonatal abstinence syndrome (opioid withdrawal) than tincture of opium (DTO) alone.

Clonidine Versus Adenosine to Treat Neuropathic Pain [Active, not recruiting]

Clonidine in Attention Deficit Hyperactivity Disorder (ADHD) in Children [Completed]
The purpose of this study is to determine the safety and efficacy of clonidine alone or in combination with methylphenidate for children 7-12 years of age with attention-deficit, hyperactivity disorder.

Study Evaluating the Safety and Efficacy of CLONICEL® to Treat Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD) [Active, not recruiting]
The purpose of this study is to determine whether CLONICEL® (clonidine HCl sustained release) is a safe and effective treatment for children and adolescents with attention deficit hyperactivity disorder (ADHD).

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Page last updated: 2009-10-20

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