Novox® (carprofen) is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that includes ibuprofen, naproxen, and ketoprofen.
Novox® is indicated for the relief of pain and inflammation associated with osteoarthritis in dogs and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Published Studies Related to Carprofen
Analgesia after feline ovariohysterectomy under midazolam-medetomidine-ketamine
anaesthesia with buprenorphine or butorphanol, and carprofen or meloxicam: a
prospective, randomised clinical trial. 
One hundred female cats undergoing routine ovariohysterectomy under
midazolam-medetomidine-ketamine anaesthesia were included in a blinded,
randomised, prospective clinical study to compare postoperative analgesia
produced by four analgesic drug combinations given preoperatively (n = 25 per
Effect of the use of carprofen in dogs undergoing intense rehabilitation after lateral fabellar suture stabilization. [2011.07.01]
OBJECTIVE: To determine whether carprofen, a commercially available NSAID, would decrease perceived exertion and signs of pain in dogs and therefore increase muscle mass and hind limb function without decreasing range of motion after lateral fabellar suture stabilization... Carprofen was not a compulsory component of a physical therapy regimen after lateral fabellar suture stabilization.
Robenacoxib vs. carprofen for the treatment of canine osteoarthritis; a randomized, noninferiority clinical trial. [2011.04.12]
Reymond, N., Speranza, C., Gruet, P., Seewald, W., King, J.In conclusion, noninferior efficacy and tolerability of robenacoxib compared with carprofen was demonstrated in dogs with osteoarthritis.
Banding or Burdizzo castration and carprofen administration on peripheral leukocyte inflammatory cytokine transcripts. [2011.02]
The objective was to investigate if Banding or Burdizzo castration of bulls would alter the gene expression profile of a range of peripheral leukocyte inflammatory cytokines (IL-1, IL-6, IL-8, IL-10, interferon-gamma and tumor necrosis factor-alpha) and to determine if the administration of carprofen (C) before castration would affect the expression of these genes...
Efficacy of carprofen on conception rates in lactating dairy cows after subcutaneous or intrauterine administration at the time of breeding. [2011.01]
Manipulation of the reproductive tract can cause inflammatory processes in the endometrium and release of cytokines and prostaglandins. It has been shown that PGF2alpha has direct negative effects on embryonic survival and development...
Reports of Suspected Carprofen Side Effects
Completed Suicide (6),
Toxicity TO Various Agents (6),
Cardio-Respiratory Arrest (3),
Ventricular Tachycardia (3),
Ventricular Fibrillation (3),
Electrocardiogram QT Prolonged (2),
Unresponsive TO Stimuli (2),
Blood PH Decreased (2),
Pco2 Increased (2), more >>
Page last updated: 2013-02-10