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Carbinoxamine (Carbinoxamine Maleate) - Summary

 
 



CARBINOXAMINE SUMMARY

Carbinoxamine Maleate Tablets, USP 4 mg
Carbinoxamine Maleate Oral Solution, 4 mg/5 mL

Carbinoxamine maleate is a histamine-H1 receptor blocking agent.

Carbinoxamine (CARBINOXAMINE) is indicated for the following:

Carbinoxamine maleate is effective for the symptomatic treatment of:

Seasonal and perennial allergic rhinitis.

Vasomotor rhinitis.

Allergic conjunctivitis due to inhalant allergens and foods.

Mild, uncomplicated allergic skin manifestations of urticaria and angioedema.

Dermatographism.

As therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.

Amelioration of the severity of allergic reactions to blood or plasma.


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NEWS HIGHLIGHTS

Published Studies Related to Carbinoxamine

Relative bioavailability of carbinoxamine and phenylephrine from a retard capsule after single and repeated dose administration in healthy subjects. [1995.09]
The plasma pharmacokinetics of carbinoxamine (CA, CAS 486-16-8) and phenylephrine (PE, CAS 59-42-7) after single dose administration of a retard capsule (Rhinopront) containing 20 mg PE hydrochloride and 4 mg CA maleate, were compared to those of the same active principles given as an aqueous solution.

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Page last updated: 2007-05-02

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