Carbamazepine (Carbamazepine) - Description

Before prescribing carbamazepine, the physician should be thoroughly familiar with the details of this prescribing information, particularly regarding use with other drugs, especially those which accentuate toxicity potential.

DESCRIPTION

Carbamazepine USP is an anticonvulsant and specific analgesic for trigeminal neuralgia, available for oral administration as chewable tablets of 100 mg and tablets of 200 mg. Its chemical name is 5 H -dibenz[ b,f ]azepine-5-carboxamide, and its structural formula is:

C ₁₅H₁₂N₂O M.W. 236.27

Carbamazepine USP is a white to off-white powder, practically insoluble in water and soluble in alcohol and in acetone.

Carbamazepine tablets USP, 200 mg contain the inactive ingredients colloidal silicon dioxide, croscarmellose sodium, ethylcellulose, glycerin, lactose monohydrate, magnesium stearate, and sodium starch glycolate.

Carbamazepine chewable tablets USP, 100 mg contain the inactive ingredients acacia, colloidal silicon dioxide, croscarmellose sodium, ethylcellulose, FD&C Red #40 aluminum lake, flavoring, glycerin, lactose monohydrate, magnesium stearate, pregelatinized corn starch, and sucrose.

Carbamazepine tablets USP, 200 mg meet USP Dissolution Test 3.

Carbamazepine chewable tablets USP, 100 mg meet USP Dissolution Test 1.