CANCIDAS SUMMARY
CANCIDAS®
(caspofungin acetate) FOR INJECTION
INTRAVENOUS INFUSION (not for IV Bolus Injection)
CANCIDAS is a sterile, lyophilized product for intravenous (IV) infusion that contains a semisynthetic lipopeptide (echinocandin) compound synthesized from a fermentation product of
Glarea lozoyensis. CANCIDAS is the first of a new class of antifungal drugs (glucan synthesis inhibitors) that inhibit the synthesis of (beta) (1,3)-D-glucan, an integral component of the fungal cell wall.
CANCIDAS is indicated for the treatment of:
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Candidemia and the following
Candida
infections: intra-abdominal abscesses, peritonitis and pleural space infections. CANCIDAS has not been studied in endocarditis, osteomyelitis, and meningitis due to
Candida.
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Esophageal Candidiasis (see CLINICAL STUDIES).
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Invasive Aspergillosis in patients who are refractory to or intolerant of other therapies (i.e., amphotericin B, lipid formulations of amphotericin B, and/or itraconazole). CANCIDAS has not been studied as initial therapy for invasive aspergillosis.
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