Cafergot (Caffeine / Ergotamine Tartrate Rectal) - Indications and Dosage

INDICATIONS AND USAGE

CAFERGOT ^® (ergotamine tartrate and caffeine)

Indicated as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants or so-called “histaminic cephalalgia”.

DOSAGE AND ADMINISTRATION

Procedure

For the best results, dosage should start at the first sign of an attack.

RECTALLY	One suppository at start of attack; second suppository after 1 hour, if needed for full relief 1 hr.

Early Aministration Gives Maximum Effectiveness

Maximum Adult Dosage

Rectally

Two suppositories is the maximum dose for an individual attack.

Total weekly dosage should not exceed 5 suppositories. CAFERGOT ^® (ergotamine tartrate and caffeine) suppositories should not be used for chronic daily administration.

In carefully selected patients, with due consideration of maximum dosage recommendations, administration of the drug at bedtime may be an appropriate short-term preventive measure.

HOW SUPPLIED

CAFERGOT ^® (ergotamine tartrate and caffeine) Suppositories, USP

Yellowish-white bullet-shaped, cocoa butter base suppositories wrapped in silver colored foil with “CAFERGOT^® SUPPOSITORY 78-33 NOVARTIS” printed in fuchsia.

Boxes of 12 (NDC 0078-0033-02).