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Cafergot (Caffeine / Ergotamine Tartrate Rectal) - Summary

 

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WARNING

Serious and/or life-threatening peripheral ischemia has been associated with the coadministration of CAFERGOT (ergotamine tartrate and caffeine) with potent CYP 3A4 inhibitors including protease inhibitors and macrolide antibiotics. Because CYP 3A4 inhibition elevates the serum levels of CAFERGOT, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the extremities is increased. Hence, concomitant use of these medications is contraindicated. (See CONTRAINDICATIONS and WARNINGS)

 

CAFERGOT SUMMARY

Cafergot®

CAFERGOT (ergotamine tartrate and caffeine) Suppository

ergotamine tartrate USP……………………………………………………………2 mg

caffeine USP…………………………………………………………………….

CAFERGOT (ergotamine tartrate and caffeine)

Indicated as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants or so-called “histaminic cephalalgia”.

CAFERGOT NEWS HIGHLIGHTS

Published Studies Related to Cafergot (Caffeine / Ergotamine Rectal)

Cost-effectiveness analysis of rizatriptan and sumatriptan versus Cafergot in the acute treatment of migraine. [2005]

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Clinical Trials Related to Cafergot (Caffeine / Ergotamine Rectal)

Treatment of Orthostatic Hypotension in Autonomic Failure [Recruiting]

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Page last updated: 2006-01-31

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