NEWS HIGHLIGHTSMedia Articles Related to Cafcit (Caffeine)
Impact Fusion International Develops Caffeine Free 2 Ounce Hangover Relief Drink
Source: Alcohol / Addiction / Illegal Drugs News From Medical News Today [2009.11.17]
Impact Fusion International (PINKSHEETS: IFUS) announced it has developed a natural caffeine free "hangover" relief beverage to be sold in a 2 ounce shot. The beverage will contain Impact Fusion International's proprietary blend Nutri-Mastic™. The product has been developed for a U.S.-based multimillion dollar beverage company with distribution in more than half of the United States Market.
Alcohol-Caffeine Combo Drinks Draw FDA Scrutiny
Source: MedPage Today Psychiatry [2009.11.13]
Companies that have begun marketing drinks that combine alcohol with caffeine will have to answer to the FDA, the agency announced.
Health Tip: Cut Back Slowly on Caffeine
Source: MedicineNet Peptic Ulcer Specialty [2009.10.12]
Title: Health Tip: Cut Back Slowly on Caffeine
Category: Health News
Created: 10/12/2009 8:10:00 AM
Last Editorial Review: 10/12/2009
Caffeine Without Healthy Diet Linked to Heart Risk
Source: MedicineNet Atrial Fibrillation Specialty [2009.09.03]
Title: Caffeine Without Healthy Diet Linked to Heart Risk
Category: Health News
Created: 9/2/2009 12:10:00 PM
Last Editorial Review: 9/3/2009
High-Octane Caffeine May Trigger Headaches
Source: MedicineNet Migraine Headache Specialty [2009.08.24]
Title: High-Octane Caffeine May Trigger Headaches
Category: Health News
Created: 8/21/2009 2:10:00 PM
Last Editorial Review: 8/24/2009
Published Studies Related to Cafcit (Caffeine)
Caffeine effects on resting-state arousal in children. [2009.09]
From previous work in our laboratory, increases in skin conductance level (SCL), together with global (across-scalp) decreases in electroencephalogram (EEG) alpha power and increases in alpha frequency, are useful indices of arousal increase, and here we sought to identify changes in these indices with caffeine ingestion in children...
Relationship of blood pressure, behavioral mood state, and physical activity following caffeine ingestion in younger and older women. [2009.08]
The purpose of this study was to examine the age-related differences in blood pressure, heart rate, and behavioral mood state after caffeine ingestion in younger and older women. Using a placebo-controlled, double-blind design, 10 younger (Y; 18-22 years) and 10 older (O; 50-67 years) healthy women who were moderate consumers of caffeine (self-reported mean intake: Y, 139 +/- 152 mg.day-1; O, 204 +/- 101 mg.day-1) were investigated...
The effect of a carbohydrate-caffeine sports drink on simulated golf performance. [2009.08]
A round of golf lasts approximately 4 h, during which time homeostasis could be challenged through either hypoglycemia or hypohydration.
Caffeine dose effect on activation-induced BOLD and CBF responses. [2009.07.01]
Caffeine is a popular psychostimulant, typically found in beverages. While low to intermediate doses of caffeine are associated with positive feelings and increased mental performance and alertness, high doses induce negative feelings such as insomnia, anxiety and nervousness...
Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers. [2009.07]
Caffeine is the world's most popular stimulant and is known to disrupt sleep... These data suggest that caffeine mimics some, but not all of the sleep disruption seen in insomnia and that its disruptive effects are differentially attenuated by the actions of sleep-promoting compounds with distinct mechanisms of action.
Clinical Trials Related to Cafcit (Caffeine)
Does Caffeine Affect the Sensitivity of Adenosine Perfusion Scans? [Suspended]
We are studying the affect of caffeine on the sensitivity of detecting coronary artery
disease (blockages in the blood flow to the heart) with adenosine tracer scans. Adenosine is
a drug used routinely in patients to relax heart blood vessels in order to assess for the
presence of coronary artery disease. Often, if patients have had caffeine, the adenosine
scan is not used because of the belief that caffeine may reduce the ability to detect
coronary artery disease. We would like to test whether caffeine affects our ability to
detect coronary artery disease with adenosine tracer scanning. We will perform an imaging
study of the heart with adenosine after you have received caffeine.
Experimental Studies of the Effects of Caffeine on Glucose Regulation [Completed]
This project contains experimental studies of the effects of the drug caffeine on glucose
regulation in adults who have Type 2 diabetes. In our experiments, we are testing the
hypothesis that moderate amounts of caffeine exaggerate the abnormal increases in glucose and
insulin observed after meals in patients with type 2 diabetes. On separate study days
subjects receive standard meals after taking capsules containing either caffeine or an
inactive placebo. We measure levels of glucose, insulin, and other chemicals in blood
samples drawn over the next 3 hours. In a separate study, we use continuous glucose
monitoring to measure glucose levels during everyday activities on days when subjects receive
caffeine or placebo.
These studies do not involve clinical treatment or disease management. However, we hope to
learn whether a very popular drug impairs the clinical management of a common disease.
Effects of Low Doses of Caffeine on Mood, Physiology and Mental Function [Completed]
It is often assumed that levels of caffeine found in ‘decaffeinated’ beverages are below any
psychopharmacological threshold. However, recent findings indicate that caffeine doses as low
as 9 mg may be psychoactive. The effects of caffeine have also been shown up to 6 hours
post-administration. The study aimed to establish the lowest active dose of caffeine, and to
ascertain the duration of any effects.
Effects of Caffeine in Tinnitus [Active, not recruiting]
The Effect of Caffeine on Ischemic Preconditioning [Completed]
Ischaemic preconditioning (IP) describes the phenomenon that brief periods of ischaemia
render the (myocardial) muscle more resistant to a subsequent more prolonged period of
ischaemia and reperfusion. Animal studies have provided evidence that adenosine receptor
stimulation is an important mediator of IP. As caffeine is an effective adenosine receptor
antagonist already at concentrations reached after regular coffee consumption, we aimed to
assess whether caffeine impairs IP in humans in vivo. We used a novel and well-validated
model to study IP in humans: 99m-Tc-annexin A5 scintigraphy in forearm skeletal muscle.
24 healthy volunteers were randomly assigned to either caffeine (4 mg/kg/iv in 10 minutes) or
saline before a protocol for IP.
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