Butalbital, Aspirin, Caffeine, and Codeine (Codeine Phosphate / Butalbital / Caffeine / Aspirin) - Description

Rx only

DESCRIPTION

Butalbital, Aspirin, Caffeine, and Codeine Phosphate Capsules, USP is supplied in capsule form for oral administration.

Each capsule contains the following active ingredients:
butalbital, USP ……………………..50 mg
aspirin, USP ……………………....325 mg
caffeine, USP ………………………40 mg
codeine phosphate, USP …………30 mg

Butalbital (5-allyl-5-isobutylbarbituric acid) is a short- to intermediate-acting barbiturate. It has the following structural formula:

C₁₁H₁₆N₂O₃                                              molecular weight 224.26

Aspirin (benzoic acid, 2-(acetyloxy)-) is an analgesic, antipyretic, and anti-inflammatory. It has the following structural formula:

C₉H₈O₄                                              molecular weight 180.16

Caffeine (1,3,7-trimethylxanthine) is a central nervous system stimulant. It has the following structural formula:

C₈H₁₀N₄O₂                                       molecular weight 194.19

Codeine phosphate (7,8-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol phosphate (1:1) (salt) hemihydrate) is a narcotic analgesic and antitussive. It has the following structural formula:

C₁₈H₂₄NO₇P                                 anhydrous molecular weight 397.37

Inactive Ingredients: microcrystalline cellulose, pregelatinized starch, talc. Gelatin capsules contain D&C Yellow No.10, FD&C Blue No.1, FD&C Red No. 3, FD&C Yellow No. 6, gelatin, titanium dioxide. The capsules are printed with edible ink containing red iron oxide.