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Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine Phosphate / Butalbital / Caffeine / Acetaminophen) - Summary

 
 



WARNING: HEPATOTOXICITY AND DEATH RELATED TO ULTRA-RAPID METABOLISM OF CODEINE TO MORPHINE

• Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.

• Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.

 

SUMMARY

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate is supplied in capsule form for oral administration.

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because codeine and butalbital are habit-forming and potentially abusable.


See all Butalbital, Acetaminophen, Caffeine, and Codeine indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine / Butalbital / Caffeine / Acetaminophen)

Headache Burden Persistent After Traumatic Brain Injury
Source: Medscape Critical Care Headlines [2016.06.22]
Patients with traumatic brain injury have persistent, migraine-like headaches that affect their lives for at least 5 years after the injury, results of a prospective study reveal.
Medscape Medical News

Headache: Surprising Headache and Migraine Triggers
Source: MedicineNet Brain Tumor Specialty [2016.06.10]
Title: Headache: Surprising Headache and Migraine Triggers
Category: Slideshows
Created: 5/18/2009 12:00:00 AM
Last Editorial Review: 6/10/2016 12:00:00 AM

Migraine Headaches: 14 Non-Drug Treatments for Migraines
Source: MedicineNet Beta Blockers Specialty [2016.06.08]
Title: Migraine Headaches: 14 Non-Drug Treatments for Migraines
Category: Slideshows
Created: 6/25/2012 12:00:00 AM
Last Editorial Review: 6/8/2016 12:00:00 AM

Migraine or Headache? Migraine Symptoms, Triggers, Treatment
Source: MedicineNet Brain Tumor Specialty [2016.05.16]
Title: Migraine or Headache? Migraine Symptoms, Triggers, Treatment
Category: Slideshows
Created: 9/2/2010 11:54:00 AM
Last Editorial Review: 5/16/2016 12:00:00 AM

Surgery for chronic temporal headaches -- simplified approach shows good results
Source: Headache / Migraine News From Medical News Today [2016.05.02]
A modified surgical technique may provide a simpler approach to the surgical treatment for one type of chronic headache, according to an "Ideas and Innovations" paper in the May issue of Plastic and...

more news >>


Page last updated: 2016-06-22

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