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Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine Phosphate / Butalbital / Caffeine / Acetaminophen) - Summary

 
 



WARNING: HEPATOTOXICITY AND DEATH RELATED TO ULTRA-RAPID METABOLISM OF CODEINE TO MORPHINE

• Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.

• Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.

 

SUMMARY

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate is supplied in capsule form for oral administration.

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because codeine and butalbital are habit-forming and potentially abusable.


See all Butalbital, Acetaminophen, Caffeine, and Codeine indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine / Butalbital / Caffeine / Acetaminophen)

Low Vitamin D Linked to Increased Headache Risk
Source: Medscape NeurologyHeadlines [2017.01.19]
Data from 2600 Finnish men showed that those with the lowest levels of serum 25-hydroxyvitamin D were more than twice as likely to report chronic headaches as those with the highest levels.
Medscape Medical News

Vitamin D deficiency increases risk of chronic headache
Source: Headache / Migraine News From Medical News Today [2017.01.04]
Vitamin D deficiency may increase the risk of chronic headache, according to a new study from the University of Eastern Finland. The findings were published in Scientific Reports.

Headache Remedies
Source: MedicineNet Dehydration Specialty [2016.11.30]
Title: Headache Remedies
Category: Diseases and Conditions
Created: 4/12/2016 12:00:00 AM
Last Editorial Review: 11/30/2016 12:00:00 AM

Visits to pediatric emergency departments for headache pain in children are on the rise
Source: Headache / Migraine News From Medical News Today [2016.10.24]
At 1 hospital, rates of emergency department visits and subsequent hospital admission doubled over a 7-year period.

Can You Blame Your Headaches on Your Thyroid?
Source: MedicineNet Hypothyroidism Specialty [2016.09.30]
Title: Can You Blame Your Headaches on Your Thyroid?
Category: Health News
Created: 9/29/2016 12:00:00 AM
Last Editorial Review: 9/30/2016 12:00:00 AM

more news >>


Page last updated: 2017-01-19

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