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Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine Phosphate / Butalbital / Caffeine / Acetaminophen) - Summary

 
 



WARNING: HEPATOTOXICITY AND DEATH RELATED TO ULTRA-RAPID METABOLISM OF CODEINE TO MORPHINE

• Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.

• Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.

 

SUMMARY

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate is supplied in capsule form for oral administration.

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because codeine and butalbital are habit-forming and potentially abusable.


See all Butalbital, Acetaminophen, Caffeine, and Codeine indications & dosage >>

NEWS HIGHLIGHTS

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Migraine or Headache? Migraine Symptoms, Triggers, Treatment
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Title: Migraine or Headache? Migraine Symptoms, Triggers, Treatment
Category: Slideshows
Created: 9/2/2010 11:54:00 AM
Last Editorial Review: 5/16/2016 12:00:00 AM

Surgery for chronic temporal headaches -- simplified approach shows good results
Source: Headache / Migraine News From Medical News Today [2016.05.02]
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Source: MedicineNet Acupuncture Specialty [2016.04.12]
Title: 17 Natural Headache Remedies and Headache Trigger Foods
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New hope on headache 'worse than childbirth': world's first fast track clinic for cluster condition opens
Source: Headache / Migraine News From Medical News Today [2016.03.20]
Health experts today launch a world first as a major boost for people who suffer what is ranked the most painful medical condition known to humankind, with its pain described by a majority of...

Migraine Headache
Source: MedicineNet Antiphospholipid Syndrome Specialty [2016.03.02]
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Page last updated: 2016-05-16

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