SUMMARY
BUTALBITAL, ACETAMINOPHEN, CAFFEINE,
AND CODEINE PHOSPHATE CAPSULES
Butalbital, acetaminophen, caffeine, and codeine phosphate is supplied in capsule form for oral administration. Each capsule contains: codeine phosphate USP, 30 mg; butalbital USP, 50 mg; caffeine USP, 40 mg; acetaminophen USP, 325 mg.
Codeine phosphate [morphine-3-methyl ether phosphate (1:1) (salt) hemihydrate, C18H24NO7P, anhydrous M.W. 397.37], is a narcotic analgesic and antitussive.
Butalbital (5-allyl-5-isobutylbarbituric acid, C11H16N2O3, M.W. 224.26), is a short- to intermediate-acting barbiturate.
Caffeine (1,3,7-trimethylxanthine, C8H10N4O2, M.W. 194.19), is a central nervous system stimulant.
Acetaminophen (4´-hydroxyacetanilide, C8H9NO2, M.W. 151.16), is a non-opiate, non-salicylate analgesic and antipyretic.
Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate Capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.
Evidence supporting the efficacy and safety of butalbital, acetaminophen, caffeine, and codeine in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because codeine and butalbital are habit-forming and potentially abusable.
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NEWS HIGHLIGHTSMedia Articles Related to Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine / Butalbital / Caffeine / Acetaminophen)
For Severe Migraine Headaches, Surgery Potentially The Best Option
Source: Headache / Migraine News From Medical News Today [2009.10.26]
The disability from migraine headaches is an enormous health burden affecting over 30 million Americans. In newly released research, 79 migraine sufferers were followed for at least five years after having undergone detection of migraine "trigger sites" and surgery. The new data finds promising outcomes for treating trigger sites surgically for migraine headaches resulting in elimination of pain for those afflicted with the condition.
Migraine Sufferers More Prone To Hangover Headache
Source: Headache / Migraine News From Medical News Today [2009.10.19]
Migraine sufferers, beware. You may be more prone to an alcohol-induced headache after a night of drinking, according to researchers from the Jefferson Headache Center. The research will be presented at Neuroscience 2009, the Annual Meeting of the Society for Neuroscience, in Chicago. Until now, studying the mechanism behind migraine and other forms of recurrent headaches has not been possible in an animal model, according to Michael Oshinsky, Ph.D.
School Days Give Some Kids a Headache
Source: MedicineNet Migraine Headache Specialty [2009.09.04]
Title: School Days Give Some Kids a Headache
Category: Health News
Created: 9/3/2009 4:10:00 PM
Last Editorial Review: 9/4/2009
NovaDel Article Published In Headache: The Journal Of Head And Face Pain
Source: Headache / Migraine News From Medical News Today [2009.09.03]
NovaDel Pharma Inc. (NYSE AMEX: NVD) announced that an article titled "Rapid Oral Transmucosal Absorption of Sumatriptan, and Pharmacodynamics in Acute Migraine" was published online on June 22, 2009 in the peer-reviewed journal Headache: The Journal of Head and Face Pain. NovaDel conducted two clinical trials evaluating sumatriptan administered via its oral spray drug delivery technology.
Leading International Headache Journal Cephalalgia To Be Published By SAGE
Source: Headache / Migraine News From Medical News Today [2009.09.03]
SAGE, the world's leading independent academic and professional publisher is delighted to announce a new agreement with the International Headache Society (IHS) to publish their official journal, Cephalalgia. Now in its 29th volume, Cephalalgia provides an international forum for original research papers, review articles and short communications on all aspects of headache.
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