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Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine Phosphate / Butalbital / Caffeine / Acetaminophen) - Summary

 
 



WARNING: HEPATOTOXICITY AND DEATH RELATED TO ULTRA-RAPID METABOLISM OF CODEINE TO MORPHINE

• Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.

• Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.

 

SUMMARY

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate is supplied in capsule form for oral administration.

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because codeine and butalbital are habit-forming and potentially abusable.


See all Butalbital, Acetaminophen, Caffeine, and Codeine indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine / Butalbital / Caffeine / Acetaminophen)

'Mutant' Lice More Hype Than Headache
Source: MedPageToday.com - medical news plus CME for physicians [2015.08.21]
(MedPage Today) -- Treatment failure doesn't equal clinical resistance

Severe Headache During Pregnancy May Signal Trouble
Source: MedicineNet Headache Specialty [2015.08.21]
Title: Severe Headache During Pregnancy May Signal Trouble
Category: Health News
Created: 8/20/2015 12:00:00 AM
Last Editorial Review: 8/21/2015 12:00:00 AM

Severe headache in pregnant women: When to worry
Source: Headache / Migraine News From Medical News Today [2015.08.20]
New findings by Montefiore and Einstein researchers offer first clinical recommendationsIf a pregnant woman with high blood pressure and no history of headache suddenly develops a headache that...

Headaches in Pregnancy May Signal Serious Illness (CME/CE)
Source: MedPageToday.com - medical news plus CME for physicians [2015.08.20]
(MedPage Today) -- Hypertension, preeclampsia most likely culprits

Health Tip: Soothing a Tension Headache
Source: MedicineNet Headache Specialty [2015.08.18]
Title: Health Tip: Soothing a Tension Headache
Category: Health News
Created: 8/18/2015 12:00:00 AM
Last Editorial Review: 8/18/2015 12:00:00 AM

more news >>


Page last updated: 2015-08-21

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