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Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine Phosphate / Butalbital / Caffeine / Acetaminophen) - Summary

 
 



WARNING: HEPATOTOXICITY AND DEATH RELATED TO ULTRA-RAPID METABOLISM OF CODEINE TO MORPHINE

• Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.

• Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.

 

SUMMARY

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate is supplied in capsule form for oral administration.

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because codeine and butalbital are habit-forming and potentially abusable.


See all Butalbital, Acetaminophen, Caffeine, and Codeine indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine / Butalbital / Caffeine / Acetaminophen)

Cluster Headaches
Source: MedicineNet Brain Aneurysm Specialty [2016.08.25]
Title: Cluster Headaches
Category: Diseases and Conditions
Created: 2/4/2005 12:00:00 AM
Last Editorial Review: 8/25/2016 12:00:00 AM

Treatment of Cluster Headache: AHS Evidence-Based Guidelines
Source: Medscape Allergy & Clinical Immunology Headlines [2016.08.23]
New evidence-based guidelines from the American Headache Society provide recommendations for the abortive and preventive treatment of cluster headache.
Headache

Tension Headache
Source: MedicineNet Cauliflower Ear Specialty [2016.08.10]
Title: Tension Headache
Category: Diseases and Conditions
Created: 2/4/2005 12:00:00 AM
Last Editorial Review: 8/10/2016 12:00:00 AM

Headache
Source: MedicineNet Anthrax Specialty [2016.07.25]
Title: Headache
Category: Diseases and Conditions
Created: 5/31/2002 12:00:00 AM
Last Editorial Review: 7/25/2016 12:00:00 AM

Can acupuncture improve quality of life for people with traumatic brain injury-related headaches?
Source: Complementary Medicine / Alternative Medicine News From Medical News Today [2016.07.01]
A study comparing the effectiveness of usual care alone to usual care plus either auricular or traditional Chinese acupuncture in treating patients with headaches due to a previous traumatic brain...

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Page last updated: 2016-08-25

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