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Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine Phosphate / Butalbital / Caffeine / Acetaminophen) - Summary

 
 



WARNING: HEPATOTOXICITY AND DEATH RELATED TO ULTRA-RAPID METABOLISM OF CODEINE TO MORPHINE

• Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.

• Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.

 

SUMMARY

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate is supplied in capsule form for oral administration.

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because codeine and butalbital are habit-forming and potentially abusable.


See all Butalbital, Acetaminophen, Caffeine, and Codeine indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine / Butalbital / Caffeine / Acetaminophen)

FDA Approves Device to Help Curb Cluster Headaches
Source: MedicineNet Headache Specialty [2017.04.20]
Title: FDA Approves Device to Help Curb Cluster Headaches
Category: Health News
Created: 4/19/2017 12:00:00 AM
Last Editorial Review: 4/20/2017 12:00:00 AM

FDA Approves Vagus Stimulation Device for Cluster Headache
Source: Medscape NeurologyHeadlines [2017.04.18]
The FDA has approved a noninvasive vagus nerve stimulation device for the treatment of pain from cluster headache in adults.
FDA Approvals

FDA Clears Noninvasive Device for Episodic Cluster Headache
Source: MedPage Today Neurology [2017.04.18]
(MedPage Today) -- VNS device not approved for chronic cluster headache

Occipital Neuralgia (A Type of Headache)
Source: MedicineNet Headache Specialty [2017.03.15]
Title: Occipital Neuralgia (A Type of Headache)
Category: Diseases and Conditions
Created: 3/11/2016 12:00:00 AM
Last Editorial Review: 3/15/2017 12:00:00 AM

Migraine Headache
Source: MedicineNet Antiphospholipid Syndrome Specialty [2017.03.13]
Title: Migraine Headache
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 3/13/2017 12:00:00 AM

more news >>


Page last updated: 2017-04-20

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