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Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine Phosphate / Butalbital / Caffeine / Acetaminophen) - Summary

 
 



WARNING: HEPATOTOXICITY AND DEATH RELATED TO ULTRA-RAPID METABOLISM OF CODEINE TO MORPHINE

• Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.

• Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.

 

SUMMARY

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate is supplied in capsule form for oral administration.

Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate capsules are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of Butalbital, Acetaminophen, Caffeine, and Codeine Phosphate in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because codeine and butalbital are habit-forming and potentially abusable.


See all Butalbital, Acetaminophen, Caffeine, and Codeine indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Butalbital, Acetaminophen, Caffeine, and Codeine (Codeine / Butalbital / Caffeine / Acetaminophen)

Headache Far More Common Stroke Symptom in Kids
Source: Medscape Critical Care Headlines [2017.02.23]
Headaches occur in close to half of children with ischemic stroke, much more often than among adults with stroke, and are most common with dissection and transient cerebral arteriopathy of childhood.
Medscape Medical News

Headache Common Stroke Symptom in Kids
Source: MedPage Today Cardiology [2017.02.23]
(MedPage Today) -- While pediatric stroke is rare, nearly half present with pain

Headaches Often Strike Before Strokes in Kids: Study
Source: MedicineNet Headache Specialty [2017.02.23]
Title: Headaches Often Strike Before Strokes in Kids: Study
Category: Health News
Created: 2/22/2017 12:00:00 AM
Last Editorial Review: 2/23/2017 12:00:00 AM

Headache far more common stroke symptom in children than adults
Source: Headache / Migraine News From Medical News Today [2017.02.22]
Headaches were present in nearly half of all children older than 3 years of age having a stroke. Headaches were most common in children with specific forms of blood vessel abnormalities.

Vitamin D deficiency increases risk of chronic headache
Source: Headache / Migraine News From Medical News Today [2017.01.04]
Vitamin D deficiency may increase the risk of chronic headache, according to a new study from the University of Eastern Finland. The findings were published in Scientific Reports.

more news >>


Page last updated: 2017-02-23

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