Hepatotoxicity
Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen containing product.
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SUMMARY
Butalbital, Acetaminophen, and Caffeine Tablets, USP are supplied in tablet form for oral administration.
Butalbital, acetaminophen, and caffeine tablets, USP are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.
Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habit-forming and potentially abusable.
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NEWS HIGHLIGHTSMedia Articles Related to Butalbital, Acetaminophen and Caffeine (Butalbital / Acetaminophen / Caffeine)
Headaches Quiz: Learn About Headache Pain
Source: MedicineNet Facial Nerve Problems Specialty [2017.09.19]
Title: Headaches Quiz: Learn About Headache Pain
Category: MedicineNet Quiz
Created: 9/28/2010 12:00:00 AM
Last Editorial Review: 9/19/2017 4:58:09 PM
Headache
Source: MedicineNet Anthrax Specialty [2017.08.16]
Title: Headache
Category: Diseases and Conditions
Created: 5/31/2002 12:00:00 AM
Last Editorial Review: 8/16/2017 12:00:00 AM
Migraine vs. Headache: Differences and Similarities
Source: MedicineNet Analgesics, Antipyretics Specialty [2017.06.26]
Title: Migraine vs. Headache: Differences and Similarities
Category: Diseases and Conditions
Created: 6/21/2017 12:00:00 AM
Last Editorial Review: 6/26/2017 12:00:00 AM
Migraine Headache
Source: MedicineNet Antiphospholipid Syndrome Specialty [2017.03.13]
Title: Migraine Headache
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 3/13/2017 12:00:00 AM
Cluster Headaches
Source: MedicineNet Cauliflower Ear Specialty [2016.08.25]
Title: Cluster Headaches
Category: Diseases and Conditions
Created: 2/4/2005 12:00:00 AM
Last Editorial Review: 8/25/2016 12:00:00 AM
Published Studies Related to Butalbital, Acetaminophen and Caffeine (Butalbital / Acetaminophen / Caffeine)
Sumatriptan-Naproxen and Butalbital: A Double-Blind, Placebo-Controlled Crossover Study. [2011.11.21]
Objectives.- The primary objective was to compare the efficacy of a sumatriptan and naproxen combination medication (SumaRT/Nap-85 mg sumatriptan and 500 mg naproxen sodium), a butalbital-containing combination medication (BCM-50 mg butalbital, 325 mg acetaminophen, 40 mg caffeine), and placebo when used to treat moderate to severe migraine headache pain in subjects who used BCMs in the past.
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Page last updated: 2017-09-19
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