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Buphenyl (Sodium Phenylbutyrate) - Current Clinical Trials

 
 



Buphenyl Related Clinical Trials

Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders [Completed]

Phenylbutyrate Therapy for Maple Syrup Urine Disease [Recruiting]

Clinical Trial of Phenylbutyrate and Vitamin D in Tuberculosis (TB) [Completed]

Mechanism of Fatty Acid-induced Impairment of Glucose-simulated Insulin Secretion - Effect of Buphenyl [Completed]

A Study of Glyceryl Tri-(4-phenylbutyrate) (GT4P) [Completed]

Comparative Efficacy of Phenylbutyrate (PBA) vs. Benzoate in Urea Cycle Disorders [Recruiting]

Pilot Study of Safety and Efficacy of Sodium Phenylbutyrate in Spinocerebellar Ataxia Type 3 [Withdrawn]

Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder [Completed]

Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer [Terminated]

Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders [Completed]

Buphenyl Therapy for Byler's Disease [No longer available]

Immune Reconstitution in HIV Disease (IREHIV) [Active, not recruiting]

Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis) [Completed]

Immune Reconstitution in Tuberculosis Disease [Active, not recruiting]

Study of the Efficacy and Safety of HPN-100, Glyceryl Tri-(4-phenylbutyrate), for the Treatment of Adults With Urea Cycle Disorders (Help UCD) [Completed]

Transition From Buphenyl to RAVICTI for the Therapy of Byler Disease [No longer available]

Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygotes (for Cystic Fibrosis) [Terminated]

Phenylbutyrate Response as a Biomarker for Alpha-synuclein Clearance From the Brain [Active, not recruiting]

Study to Evaluate Sodium Phenylbutyrate in Pre-symptomatic Infants With Spinal Muscular Atrophy [Completed]

Safety and Tolerability Study of Phenylbutyrate in Huntington's Disease (PHEND-HD) [Completed]

Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Type I [Terminated]

Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Types II or III [Terminated]

Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous(for Cystic Fibrosis) [Completed]

Phenylbutyrate in Treating Patients With Refractory Solid Tumors or Lymphoma [Completed]

A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders (UCDs) [Recruiting]

Glycerol Phenylbutyrate Corrector Therapy For CF [Not yet recruiting]

Phenylbutyrate to Treat Children With Progressive or Recurrent Brain Tumors [Completed]

Phenylbutyrate and Valganciclovir in Treating Patients With Relapsed or Refractory Epstein-Barr Virus-Positive Cancer [Active, not recruiting]

Azacitidine Plus Phenylbutyrate in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Completed]

Phenylbutyrate Plus Azacitidine in Treating Patients With Acute Myeloid Leukemia, Myelodysplasia, Non-Hodgkin's Lymphoma, Multiple Myeloma, Non-small Cell Lung Cancer, or Prostate Cancer [Completed]

Phenylbutyrate, Dexamethasone, and Sargramostim in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia [Completed]

Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy [Completed]

Azacitidine Plus Phenylbutyrate in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Treatment [Completed]

5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia [Completed]

Phenylbutyrate in Proteinuric Nephropathies [Not yet recruiting]

Phenylbutyrate and Tretinoin in Treating Patients With Hematologic Cancer [Completed]

Phase II Study of Azacitidine and Phenylbutyrate in Patients With Thalassemia Major [Terminated]

Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders [Completed]

To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs) [Active, not recruiting]

Study of the Safety of HPN (Hyperion)-100 for the Long-Term Treatment of Urea Cycle Disorders (Treat UCD) [Completed]

Effect of Endoplasmic Reticulum Stress on Metabolic Function [Completed]

Study of the Safety, Pharmacokinetics and Efficacy of HPN-100, in Pediatric Subjects With Urea Cycle Disorders (UCDs) [Completed]

A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group [Completed]

Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs) [Recruiting]

4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency? [Completed]

Expanded Access Protocol for an Intermediate Size Population - RAVICTI for Byler Disease [Temporarily not available]

A Study of the Safety and Efficacy of HPN-100 for Maintaining Remission in Subjects With Cirrhosis and Episodic Hepatic Encephalopathy (HALT-HE) [Completed]

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