BONTRIL PDM SUMMARY
BONTRIL PDM (phendimetrazine tartrate) is a sympathomimetic amine with pharmacological activity similar to the prototype drugs of this class used in obesity, the amphetamines.
Bontril® PDM (phendimetrazine tartrate) is indicated in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction. The limited usefulness of agents of this class (see CLINICAL PHARMACOLOGY) should be measured against possible risk factors inherent in their use such as those described below.
Media Articles Related to Bontril PDM (Phendimetrazine)
Obesity and stress
Source: Anxiety / Stress News From Medical News Today [2014.07.17]
Using experimental models, researchers at Boston University School of Medicine (BUSM) showed that adenosine, a metabolite released when the body is under stress or during an inflammatory response...
Is Obesity an Advantage After Heart Procedures?
Source: MedicineNet Heart Attack Specialty [2014.07.17]
Title: Is Obesity an Advantage After Heart Procedures?
Category: Health News
Created: 7/16/2014 2:35:00 PM
Last Editorial Review: 7/17/2014 12:00:00 AM
Severe Obesity Has Decreased in New York City Schoolkids
Source: Medscape Pediatrics Headlines [2014.07.15]
Overall obesity and severe obesity both decreased in New York City public elementary and middle school students between 2006 to 2007 and 2010 to 2011.
Medscape Medical News
Obesity - surgery is not the only answer, say research scientists
Source: GastroIntestinal / Gastroenterology News From Medical News Today [2014.07.15]
Research scientists predict that gastric bypass surgery to treat obesity could be a thing of the past.
How Twitter can be used to address specific health issues, like childhood obesity
Source: Obesity / Weight Loss / Fitness News From Medical News Today [2014.07.15]
Childhood obesity is one of the top public health concerns in the United States, with 32 percent of youths aged 2-19 classified as obese as of 2012.
Published Studies Related to Bontril PDM (Phendimetrazine)
Rare case of rhabdomyolysis with therapeutic doses of phendimetrazine tartrate. [2006.03]
Phendimetrazine tartrate is a newer drug that acts as a central stimulant and indirectly acting sympathomimetic with a host of uses similar to the class amphetamines... Additional awareness is needed to educate their patients about the side effects associated with these drugs and to strongly discourage their unsupervised use.
Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine. [1998.10]
A 47-year-old mildly obese female began a weight reduction program that included anorectic therapy with phentermine and phendimetrazine. A normal urinalysis and serum creatinine were documented at the start of therapy... This case represents the first report of acute interstitial nephritis associated with phentermine or phendimetrazine.
A simple gas chromatographic identification and determination of 11 CNS stimulants in biological samples. Application on a fatality involving phendimetrazine. [1989.02]
A method is presented for the simultaneous identification and quantification of several CNS stimulants, including amphetamine in plasma and urine by GC/FID using mephentermine as an internal standard.
Fatality from illicit phendimetrazine use. 
Phendimetrazine is an anorectic agent which recently has been detected in three medical examiner's cases. In one instance death was attributed to this drug... In the one instance where death was attributed to this substance, the blood concentration was 300 ng/ml.