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Bontril PDM (Phendimetrazine Tartrate) - Summary

 
 



BONTRIL PDM SUMMARY

BONTRIL PDM (phendimetrazine tartrate) is a sympathomimetic amine with pharmacological activity similar to the prototype drugs of this class used in obesity, the amphetamines.

Bontril PDM (phendimetrazine tartrate) is indicated in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction. The limited usefulness of agents of this class (see CLINICAL PHARMACOLOGY) should be measured against possible risk factors inherent in their use such as those described below.


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NEWS HIGHLIGHTS

Media Articles Related to Bontril PDM (Phendimetrazine)

New research highlights public demand for health technology to combat obesity epidemic
Source: IT / Internet / E-mail News From Medical News Today [2014.10.17]
A Government minister today will highlight the findings of the first AXA PPP Health Tech & You State of the Nation survey which reveals the nation's attitudes towards health technology and how...

e-healthcare may help reverse the trend of high CVD and obesity in China
Source: IT / Internet / E-mail News From Medical News Today [2014.10.17]
The use of electronic health care services (versus more traditional methods) to reduce the high incidence of heart disease in China will be debated by leading cardiologists from around the world in...

Gut Microbiome May Be Key Link Between Jet Lag and Obesity
Source: Medscape Allergy & Clinical Immunology Headlines [2014.10.16]
Humans and mice showed disruptions in their gut microbes with jet lag; and jet-lagged mice gained weight in response to those changes.
Medscape Medical News

It Takes A Village to Curb Childhood Obesity
Source: Medscape Pediatrics Headlines [2014.10.16]
A group intervention program that involves families, a dietician, and a psychologist dramatically reduces the rate of weight gain in babies and toddlers.
Medscape Medical News

Obesity and Depression Often Twin Ills, Study Finds
Source: MedicineNet Depression Specialty [2014.10.16]
Title: Obesity and Depression Often Twin Ills, Study Finds
Category: Health News
Created: 10/16/2014 12:00:00 AM
Last Editorial Review: 10/16/2014 12:00:00 AM

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Published Studies Related to Bontril PDM (Phendimetrazine)

Rare case of rhabdomyolysis with therapeutic doses of phendimetrazine tartrate. [2006.03]
Phendimetrazine tartrate is a newer drug that acts as a central stimulant and indirectly acting sympathomimetic with a host of uses similar to the class amphetamines... Additional awareness is needed to educate their patients about the side effects associated with these drugs and to strongly discourage their unsupervised use.

Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine. [1998.10]
A 47-year-old mildly obese female began a weight reduction program that included anorectic therapy with phentermine and phendimetrazine. A normal urinalysis and serum creatinine were documented at the start of therapy... This case represents the first report of acute interstitial nephritis associated with phentermine or phendimetrazine.

A simple gas chromatographic identification and determination of 11 CNS stimulants in biological samples. Application on a fatality involving phendimetrazine. [1989.02]
A method is presented for the simultaneous identification and quantification of several CNS stimulants, including amphetamine in plasma and urine by GC/FID using mephentermine as an internal standard.

Fatality from illicit phendimetrazine use. [1988]
Phendimetrazine is an anorectic agent which recently has been detected in three medical examiner's cases. In one instance death was attributed to this drug... In the one instance where death was attributed to this substance, the blood concentration was 300 ng/ml.

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Page last updated: 2014-10-17

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