DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Bontril PDM (Phendimetrazine Tartrate) - Summary

 
 



BONTRIL PDM SUMMARY

BONTRIL PDM (phendimetrazine tartrate) is a sympathomimetic amine with pharmacological activity similar to the prototype drugs of this class used in obesity, the amphetamines.

Bontril® PDM (phendimetrazine tartrate) is indicated in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction. The limited usefulness of agents of this class (see CLINICAL PHARMACOLOGY) should be measured against possible risk factors inherent in their use such as those described below.


See all Bontril PDM indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Bontril PDM (Phendimetrazine)

More than 100 members of congress ask for passage of The Treat and Reduce Obesity Act of 2015
Source: Obesity / Weight Loss / Fitness News From Medical News Today [2015.07.31]
The Treat and Reduce Obesity Act (TROA) of 2015 (HR 2404 and S 1509) continues to gain momentum with 101 members of the House of Representatives and 10 members of the Senate co-sponsoring this...

Countering pet obesity by rethinking feeding habits
Source: Obesity / Weight Loss / Fitness News From Medical News Today [2015.07.31]
Reevaluation of pet feeding regimens could spell healthier animal companions190 million Americans share the luxuries of human life with their pets.

Friday Feedback: Expanding Options to Treat Obesity
Source: MedPageToday.com - medical news plus CME for physicians [2015.07.31]
(MedPage Today) -- Experts weigh in on pros and cons of new treatments

Toward a safe antiobesity drug that could block fat absorption
Source: Depression News From Medical News Today [2015.07.30]
To help address the global obesity epidemic, scientists are developing a new class of compounds called "micelle sequestrant polymers," or MSPs, that could prevent fat particles from getting absorbed...

FDA approves non-surgical temporary balloon device to treat obesity
Source: Medical Devices / Diagnostics News From Medical News Today [2015.07.29]
The U.S. Food and Drug Administration has approved a new balloon device to treat obesity without the need for invasive surgery.

more news >>

Published Studies Related to Bontril PDM (Phendimetrazine)

Rare case of rhabdomyolysis with therapeutic doses of phendimetrazine tartrate. [2006.03]
Phendimetrazine tartrate is a newer drug that acts as a central stimulant and indirectly acting sympathomimetic with a host of uses similar to the class amphetamines... Additional awareness is needed to educate their patients about the side effects associated with these drugs and to strongly discourage their unsupervised use.

Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine. [1998.10]
A 47-year-old mildly obese female began a weight reduction program that included anorectic therapy with phentermine and phendimetrazine. A normal urinalysis and serum creatinine were documented at the start of therapy... This case represents the first report of acute interstitial nephritis associated with phentermine or phendimetrazine.

A simple gas chromatographic identification and determination of 11 CNS stimulants in biological samples. Application on a fatality involving phendimetrazine. [1989.02]
A method is presented for the simultaneous identification and quantification of several CNS stimulants, including amphetamine in plasma and urine by GC/FID using mephentermine as an internal standard.

Fatality from illicit phendimetrazine use. [1988]
Phendimetrazine is an anorectic agent which recently has been detected in three medical examiner's cases. In one instance death was attributed to this drug... In the one instance where death was attributed to this substance, the blood concentration was 300 ng/ml.

more studies >>

Clinical Trials Related to Bontril PDM (Phendimetrazine)

Phendimetrazine and Cocaine [Recruiting]
This study will determine the safety and tolerability of phendimetrazine (Bontril®) as a pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will be conducted in which the subjective and physiological effects of cocaine are evaluated during maintenance on placebo and phendimetrazine.

Efficacy of Natural Vitamin E Tocotrienol on the Treatment of Surgical Scars [Recruiting]
The overall goal of this study is to determine the efficacy of tocotrienol (TCT), a natural form of vitamin E, in preventing or reducing scar formation in human skin wounds as well as the basal levels of TCT in normal human skin and adipose tissue.

more trials >>


Page last updated: 2015-07-31

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2015