DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Bontril PDM (Phendimetrazine Tartrate) - Summary

 
 



BONTRIL PDM SUMMARY

BONTRIL PDM (phendimetrazine tartrate) is a sympathomimetic amine with pharmacological activity similar to the prototype drugs of this class used in obesity, the amphetamines.

Bontril® PDM (phendimetrazine tartrate) is indicated in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction. The limited usefulness of agents of this class (see CLINICAL PHARMACOLOGY) should be measured against possible risk factors inherent in their use such as those described below.


See all Bontril PDM indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Bontril PDM (Phendimetrazine)

Obesity Increases SCD Risk in Middle-Aged Nonsmokers
Source: Medscape Medical News Headlines [2014.12.12]
The ARIC study again shows that routine measures of obesity, especially the waist-to-hip ratio, are significantly associated with an increased risk of sudden cardiac death among middle-aged citizens who do not smoke.
Heartwire

Advances in Obesity Management: 2014
Source: Medscape Diabetes & Endocrinology Headlines [2014.12.11]
Dr Fatima Stanford reviews the year's developments in obesity treatment and understanding.
Medscape Diabetes & Endocrinology

Short sleep and breathing problems increase obesity risk for kids
Source: Obesity / Weight Loss / Fitness News From Medical News Today [2014.12.11]
Two modifiable sleep disorders, chronic sleep loss and sleep-related breathing problems, double the risk of a child being obese by the age of 15, according to a new study.

For Young Kids, Too Little Sleep Linked to Later Obesity
Source: MedicineNet Obesity (Weight Loss) Specialty [2014.12.11]
Title: For Young Kids, Too Little Sleep Linked to Later Obesity
Category: Health News
Created: 12/11/2014 12:00:00 AM
Last Editorial Review: 12/11/2014 12:00:00 AM

Rule of three: hormone triplet offers hope for obesity and diabetes
Source: Diabetes News From Medical News Today [2014.12.09]
A new substance that unifies the action profiles of three gastrointestinal hormones lowers the blood sugar level and reduces body fat considerably beyond existing drugs.

more news >>

Published Studies Related to Bontril PDM (Phendimetrazine)

Rare case of rhabdomyolysis with therapeutic doses of phendimetrazine tartrate. [2006.03]
Phendimetrazine tartrate is a newer drug that acts as a central stimulant and indirectly acting sympathomimetic with a host of uses similar to the class amphetamines... Additional awareness is needed to educate their patients about the side effects associated with these drugs and to strongly discourage their unsupervised use.

Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine. [1998.10]
A 47-year-old mildly obese female began a weight reduction program that included anorectic therapy with phentermine and phendimetrazine. A normal urinalysis and serum creatinine were documented at the start of therapy... This case represents the first report of acute interstitial nephritis associated with phentermine or phendimetrazine.

A simple gas chromatographic identification and determination of 11 CNS stimulants in biological samples. Application on a fatality involving phendimetrazine. [1989.02]
A method is presented for the simultaneous identification and quantification of several CNS stimulants, including amphetamine in plasma and urine by GC/FID using mephentermine as an internal standard.

Fatality from illicit phendimetrazine use. [1988]
Phendimetrazine is an anorectic agent which recently has been detected in three medical examiner's cases. In one instance death was attributed to this drug... In the one instance where death was attributed to this substance, the blood concentration was 300 ng/ml.

more studies >>

Clinical Trials Related to Bontril PDM (Phendimetrazine)

Phendimetrazine and Cocaine [Recruiting]
This study will determine the safety and tolerability of phendimetrazine (Bontril®) as a pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will be conducted in which the subjective and physiological effects of cocaine are evaluated during maintenance on placebo and phendimetrazine.

Efficacy of Natural Vitamin E Tocotrienol on the Treatment of Surgical Scars [Recruiting]
The overall goal of this study is to determine the efficacy of tocotrienol (TCT), a natural form of vitamin E, in preventing or reducing scar formation in human skin wounds as well as the basal levels of TCT in normal human skin and adipose tissue.

more trials >>


Page last updated: 2014-12-12

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2014