DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Bontril PDM (Phendimetrazine Tartrate) - Summary

 
 



BONTRIL PDM SUMMARY

BONTRIL PDM (phendimetrazine tartrate) is a sympathomimetic amine with pharmacological activity similar to the prototype drugs of this class used in obesity, the amphetamines.

Bontril® PDM (phendimetrazine tartrate) is indicated in the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction. The limited usefulness of agents of this class (see CLINICAL PHARMACOLOGY) should be measured against possible risk factors inherent in their use such as those described below.


See all Bontril PDM indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Bontril PDM (Phendimetrazine)

Living Near Fast-Food Outlets Might Boost Obesity Risk
Source: MedicineNet Diabetes Mellitus Specialty [2013.05.17]
Title: Living Near Fast-Food Outlets Might Boost Obesity Risk
Category: Health News
Created: 5/16/2013 4:35:00 PM
Last Editorial Review: 5/17/2013 12:00:00 AM

Gut Bug May Prevent Obesity And Type 2 Diabetes
Source: Biology / Biochemistry News From Medical News Today [2013.05.15]
A Belgian-led study published in PNAS this week suggests Akkermansia muciniphila, an intestinal microbe that is important for maintaining the gut lining and how food is absorbed, could be used to prevent obesity and associated metabolic disorders, such as those that lead to type 2 diabetes. Our digestive tract is home to a vast and varied population of microbes...

Obesity-Related Dementia Is Projected To Rise In England
Source: Obesity / Weight Loss / Fitness News From Medical News Today [2013.05.15]
The rise in obesity in England if unchecked could lead to an estimated increase in dementia prevalence in over 65 year olds by 2050 from 5% to 7% (4,894 cases per 100,000 in 2010 to 6,662 cases per 100,000), conclude researchers at this year's European Congress on Obesity (ECO), taking place in Liverpool, UK (12-15 May)...

60 Years Of Data Suggest A Link Between Obesity And Height In Childhood And Endometrial Cancer In Adulthood
Source: Cancer / Oncology News From Medical News Today [2013.05.14]
New research presented at the European Congress in Liverpool (ECO) beginning today (Sunday 12 May) shows a possible link between obesity and height in childhood and endometrial cancer in adulthood. The research* is by Julie Aarestrup, Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark, and colleagues...

20th European Congress on Obesity (ECO)
Source: Medscape Diabetes & Endocrinology Headlines [2013.05.13]
Read clinically focused news coverage of key developments from ECO 2013.
Medscape Diabetes & Endocrinology

more news >>

Published Studies Related to Bontril PDM (Phendimetrazine)

Rare case of rhabdomyolysis with therapeutic doses of phendimetrazine tartrate. [2006.03]
Phendimetrazine tartrate is a newer drug that acts as a central stimulant and indirectly acting sympathomimetic with a host of uses similar to the class amphetamines... Additional awareness is needed to educate their patients about the side effects associated with these drugs and to strongly discourage their unsupervised use.

Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine. [1998.10]
A 47-year-old mildly obese female began a weight reduction program that included anorectic therapy with phentermine and phendimetrazine. A normal urinalysis and serum creatinine were documented at the start of therapy... This case represents the first report of acute interstitial nephritis associated with phentermine or phendimetrazine.

A simple gas chromatographic identification and determination of 11 CNS stimulants in biological samples. Application on a fatality involving phendimetrazine. [1989.02]
A method is presented for the simultaneous identification and quantification of several CNS stimulants, including amphetamine in plasma and urine by GC/FID using mephentermine as an internal standard.

Fatality from illicit phendimetrazine use. [1988]
Phendimetrazine is an anorectic agent which recently has been detected in three medical examiner's cases. In one instance death was attributed to this drug... In the one instance where death was attributed to this substance, the blood concentration was 300 ng/ml.

more studies >>


Page last updated: 2013-05-17

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2012