Media Articles Related to Bontril PDM (Phendimetrazine)
Distal vs Standard Gastric Bypass in Severe Obesity
Source: Medscape General Surgery Headlines [2016.09.23]
For patients with an extremely high BMI, distal Roux-en-Y gastric bypass is no more effective than the standard procedure, and is associated with serious adverse effects, researchers in Norway report.
Reuters Health Information
Childhood Obesity May Impact Risk for Adult Knee OA (CME/CE)
Source: MedPageToday.com - medical news plus CME for physicians [2016.09.23]
(MedPage Today) -- Review highlights need to control for risk factors early in life
Obesity Gene Shows No Effect on Weight Loss, Review Suggests
Source: Medscape Diabetes & Endocrinology Headlines [2016.09.21]
People with the FTO obesity gene respond to weight-loss treatments as well as the rest of the population; an expert emphasizes the importance of environmental factors over genes in weight loss.
Medscape Medical News
Medical News Today: Gut bacteria may affect obesity risk in youth
Source: Featured Health News from Medical News Today [2016.09.21]
Children and adolescents who are obese have different populations of gut microbes compared with youths of a normal weight, new research finds.
'Obesity gene' does not hinder weight loss
Source: Genetics News From Medical News Today [2016.09.21]
The belief that so-called obesity genes can hinder weight loss is called into question by a new study review. Genetics may not be so vital after all.
Published Studies Related to Bontril PDM (Phendimetrazine)
Rare case of rhabdomyolysis with therapeutic doses of phendimetrazine tartrate. [2006.03]
Phendimetrazine tartrate is a newer drug that acts as a central stimulant and indirectly acting sympathomimetic with a host of uses similar to the class amphetamines... Additional awareness is needed to educate their patients about the side effects associated with these drugs and to strongly discourage their unsupervised use.
Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine. [1998.10]
A 47-year-old mildly obese female began a weight reduction program that included anorectic therapy with phentermine and phendimetrazine. A normal urinalysis and serum creatinine were documented at the start of therapy... This case represents the first report of acute interstitial nephritis associated with phentermine or phendimetrazine.
A simple gas chromatographic identification and determination of 11 CNS stimulants in biological samples. Application on a fatality involving phendimetrazine. [1989.02]
A method is presented for the simultaneous identification and quantification of several CNS stimulants, including amphetamine in plasma and urine by GC/FID using mephentermine as an internal standard.
Fatality from illicit phendimetrazine use. 
Phendimetrazine is an anorectic agent which recently has been detected in three medical examiner's cases. In one instance death was attributed to this drug... In the one instance where death was attributed to this substance, the blood concentration was 300 ng/ml.
Clinical Trials Related to Bontril PDM (Phendimetrazine)
Reinforcing Effects of Cocaine During Phendimetrazine Maintenance [Recruiting]
This study will determine the initial efficacy of phendimetrazine as a pharmacotherapy for
cocaine dependence. A rigorous, inpatient human laboratory study will be conducted in which
the subjective, physiological and reinforcing effects of cocaine are evaluated during
maintenance on placebo and phendimetrazine.
Phendimetrazine and Cocaine [Recruiting]
This study will determine the safety and tolerability of phendimetrazine (Bontril«) as a
pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will
be conducted in which the subjective and physiological effects of cocaine are evaluated
during maintenance on placebo and phendimetrazine.
Stemcells for Radiation Induced Xerostomia [Enrolling by invitation]
The current study aims to assess the safety and feasibility of the injection of autologous
adipost tissue derived MSCs on radiation-induced salivary gland hypofunction and xerostomia
in head and neck cancer participants. The project can potentially help to develop a
clinically relevant treatment option for the growing number of patients suffering from
xerostomia after radiotherapy. The development of new therapies is especially important,
since only sub-optimal symptomatic treatments are currently available and the symptom of
xerostomia greatly reduces the quality of life.
Efficacy of Natural Vitamin E Tocotrienol on the Treatment of Surgical Scars [Recruiting]
The overall goal of this study is to determine the efficacy of tocotrienol (TCT), a natural
form of vitamin E, in preventing or reducing scar formation in human skin wounds as well as
the basal levels of TCT in normal human skin and adipose tissue.