Media Articles Related to Boniva Injection (Ibandronic Acid)
Comparison of side effects, efficacy of osteoporosis drugs
Source: Bones / Orthopedics News From Medical News Today [2013.12.05]
A study comparing the efficacy and tolerability of two popular osteoporosis drugs, denosumab and zoledronic acid, found that denosumab had a significantly greater effect on increasing spine bone mineral density and zoledronic acid caused more flulike symptoms. These findings were presented recently at the American Society for Bone and Mineral Research's annual meeting.
Treating parasitic infections with statin, osteoporosis drug combo
Source: Statins News From Medical News Today [2013.10.21]
Researchers at the University of Georgia have discovered that a combination of two commonly prescribed drugs used to treat high cholesterol and osteoporosis may serve as the foundation of a new treatment for toxoplasmosis, a parasitic infection caused by the protozoan Toxoplasma gondii. They published their findings recently in PLOS Pathogens.
New Insights Into Patient And Physician Characteristics That Contribute To Osteoporosis Medication Adherence
Source: Compliance News From Medical News Today [2013.04.22]
Nearly 30 percent of women failed to pick up their bisphosphonate prescriptions, a medication that is most commonly used to treat osteoporosis and similar bone diseases, according to a Kaiser Permanente study published in the journal Osteoporosis International.
Nearly 30 Percent Of Women Fail To Pick Up New Prescriptions For Osteoporosis, Kaiser Permanente Study Finds
Source: Compliance News From Medical News Today [2013.04.20]
Study offers new insights on patient and physician characteristics that contribute to osteoporosis medication adherenceNearly 30 percent of women failed to pick up their bisphosphonate prescriptions, a medication that is most commonly used to treat osteoporosis and similar bone diseases, according to a Kaiser Permanente study published this week in the journal Osteoporosis International.
Osteoporosis Quiz: Test Your Medical IQ
Source: MedicineNet alendronate Specialty [2012.08.09]
Title: Osteoporosis Quiz: Test Your Medical IQ
Category: MedicineNet Quiz
Created: 1/14/2011 2:27:00 PM
Last Editorial Review: 8/9/2012 12:49:40 PM
Published Studies Related to Boniva Injection (Ibandronic Acid)
Long-term safety of intravenous ibandronic acid for up to 4 years in metastatic breast cancer: an open-label trial. 
BACKGROUND AND OBJECTIVE: Despite their widespread use in metastatic bone disease, some bisphosphonate drugs are associated with adverse events (AEs), particularly renal toxicity, adding to treatment burdens and increasing healthcare costs. Ibandronic acid is a single-nitrogen bisphosphonate with high efficacy against bone events and metastatic bone pain, and a renal safety profile compar- able to that of placebo. In this study, the safety of ibandronic acid was examined over a period of 4 years... CONCLUSION: This 96-week open-label safety extension of a phase III, placebo-controlled trial demonstrates that long-term use of intravenous ibandronic acid is well tolerated.
Patient preference for once-monthly ibandronate versus once-weekly alendronate in a randomized, open-label, cross-over trial: the Boniva Alendronate Trial in Osteoporosis (BALTO). [2005.12]
CONCLUSIONS: Significantly more women with postmenopausal osteoporosis preferred once-monthly ibandronate therapy to once-weekly alendronate therapy, and found the once-monthly regimen to be more convenient. Ease of following a treatment regimen for a long time was the most common reason given for the patients' preferences.
Renal function changes and NHS resource use in breast cancer patients with metastatic bone disease treated with IV zoledronic acid or oral ibandronic acid: a four-centre non-interventional study. [2010.03]
AIMS: To describe renal function monitoring practice in patients with metastatic bone disease (MBD) treated with IV zoledronic acid (ZA) and oral ibandronic acid (IA), the management pathways and NHS hospital resources used... CONCLUSION: Although limited by retrospective design, these results demonstrate that in many patients, CrCl is not calculated before or during treatment with bisphosphonates. Renal function deteriorated in many patients during therapy. In view of these effects, practice should be reviewed to ensure appropriate dosing.
Oral versus intravenous ibandronic acid: a comparison of treatment options for metastatic bone disease. [2008.12]
PURPOSE: This trial is the first to compare directly the clinical response to and safety of oral and intravenous (IV) ibandronic acid for metastatic bone disease... CONCLUSION: Oral and IV ibandronic acid for bone metastases have similar efficacy and tolerability.
Managing neoplastic bone disease with ibandronic acid: a preclinical and clinical data update. [2008.12]
CONCLUSIONS: Ibandronate remains the only bisphosphonate with approved oral and intravenous formulations; ibandronate should be considered when designing a bisphosphonate-containing regimen for patients with bone metastases from breast cancer.
Clinical Trials Related to Boniva Injection (Ibandronic Acid)
BONVIVA(Ibandronate) PMS(Post-marketing Surveillance ) [Recruiting]
BONCURE Study: A Study of Monthly Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis on Bisphosphonate Therapy. [Active, not recruiting]
This single arm study will assess patient preference for monthly Bonviva, versus daily or
weekly alendronate or risedronate, in the treatment of postmenopausal osteoporosis. Patients
currently on a daily or weekly regimen of bisphosphonate therapy (alendronate or risedronate)
will answer a questionnaire to identify patients who may benefit from a monthly Bonviva
regimen. Eligible patients will then discontinue their present bisphosphonate treatment, and
switch to monthly Bonviva 150mg po. At the beginning and end of Bonviva treatment, all
patients will complete an Osteoporosis Patient Satisfaction Questionnaire. The anticipated
time on study treatment is 3-12 months, and the target sample size is 500+ individuals.
A Study of Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis Previously Treated With Bonviva [Completed]
This 2 arm study will assess the long-term efficacy and safety of oral treatment with 100mg
or 150mg Bonviva in women with post-menopausal osteoporosis who have previously completed
Bonviva study BM16549 (MOBILE study). Patients will receive Bonviva either 100mg po monthly,
or 150mg po monthly. Patients will also receive daily supplementation with vitamin D and
calcium. The anticipated time of study treatment is 2+ years, and the target sample size is
BONVIVA(Ibandronate) Injection PMS(Post-marketing Surveillance) [Recruiting]
BEATRIS Study: A Study of Adherence to Bonviva (Ibandronate) Once Monthly in Women With Post-Menopausal Osteoporosis [Active, not recruiting]
This 2 arm study will assess the impact of Bone Marker Feedback (BMF), using blood sampling
and communication of the results at 2 months, on adherence to monthly Bonviva (150mg po) in
women with post-menopausal osteoporosis. Patients will be randomized into either 1) a group
which receives bone marker feedback or 2)a group which does not receive feedback on the
results. The study will also assess patient satisfaction with treatment with once monthly
Bonviva. The anticipated time on study treatment is 3-12 months, and the target sample size
is 500+ individuals.