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Betamethasone (Betamethasone Dipropionate Topical) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

The following local adverse reactions are reported infrequently when Betamethasone Dipropionate Cream is used as recommended in the DOSAGE AND ADMINISTRATION section. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, miliaria.

Adverse reactions reported to be possibly or probably related to treatment with betamethasone dipropionate cream during a pediatric clinical study include signs of skin atrophy (bruising, shininess). Skin atrophy occurred in 3 of 63 (5%) patients, a 3-year old, a 5-year old, and a 7-year old.

Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria in some patients.



REPORTS OF SUSPECTED BETAMETHASONE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Betamethasone. The information is not vetted and should not be considered as verified clinical evidence.

Possible Betamethasone side effects / adverse reactions in 62 year old male

Reported by a physician from Japan on 2011-10-04

Patient: 62 year old male weighing 70.0 kg (154.0 pounds)

Reactions: Cerebral Haemorrhage

Adverse event resulted in: hospitalization

Suspect drug(s):
Tolterodine Tartrate
    Dosage: 4 mg, 1x/day
    Administration route: Oral
    Indication: Hypertonic Bladder
    Start date: 2010-11-19
    End date: 2011-03-26

Magnesium Sulfate
    Dosage: 330 mg, 2x/day
    Administration route: Oral
    Indication: Constipation
    Start date: 2008-09-01
    End date: 2011-03-27

Pregabalin
    Dosage: 75 mg, 2x/day
    Administration route: Oral
    Indication: Pain
    Start date: 2010-10-25
    End date: 2011-03-27

Brotizolam
    Dosage: 0.25 mg, 1x/day
    Administration route: Oral
    Indication: Insomnia
    Start date: 2009-05-13
    End date: 2011-03-27

Livostin
    Dosage: 3 or 4 times daily
    Indication: Conjunctivitis Allergic
    Start date: 2010-10-01
    End date: 2011-03-27

Betamethasone
    Dosage: unk
    Start date: 2011-03-02
    End date: 2011-03-27

Amlodipine Besylate
    Dosage: 5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-10-29
    End date: 2011-03-27

Zoloft
    Dosage: 25 mg, 2x/day
    Administration route: Oral
    Indication: Depression
    Start date: 2008-06-26
    End date: 2011-03-27

Isosorbide Dinitrate
    Dosage: 20 mg, 2x/day
    Administration route: Oral
    Indication: Angina Pectoris
    Start date: 2008-05-22
    End date: 2011-03-27

Cyanocobalamin
    Dosage: 3 or 4 times daily
    Indication: Asthenopia
    Start date: 2010-10-01
    End date: 2011-03-27

Allegra D 24 Hour
    Dosage: 60 mg, 2x/day
    Administration route: Oral
    Indication: Pustular Psoriasis
    Start date: 2011-03-02
    End date: 2011-03-27

Ketoprofen
    Dosage: unk
    Indication: Back Pain
    Start date: 2008-06-01
    End date: 2011-03-27

Olmesartan Medoxomil
    Dosage: 20 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-05-01
    End date: 2011-03-27

Betamethasone
    Dosage: unk
    Indication: Pustular Psoriasis
    Start date: 2008-10-24
    End date: 2011-03-27

Phenobarbital TAB
    Dosage: 30 mg, 3x/day
    Administration route: Oral
    Indication: Epilepsy
    Start date: 2008-01-01
    End date: 2011-03-27

Loxoprofen Sodium
    Dosage: 60 mg, as needed
    Administration route: Oral
    Indication: Pain
    Start date: 2009-05-07
    End date: 2011-03-27



Possible Betamethasone side effects / adverse reactions in 20 year old male

Reported by a health professional (non-physician/pharmacist) from Iran (Islamic Republic OF) on 2011-10-06

Patient: 20 year old male

Reactions: Scleritis, Anterior Chamber Disorder, Eye Discharge, Eye Pain, Disease Progression, Injection Site Necrosis, Eye Infection Staphylococcal, Corneal Oedema, Culture Positive

Suspect drug(s):
Betamethasone
    Dosage: q2hr, io
    Indication: Corneal Graft Rejection

Chloramphenicol
    Dosage: q8hr, io
    Indication: Corneal Graft Rejection

Triamcinolone Acetonide
    Dosage: 20 mg,. 1x, io
    Indication: Corneal Graft Rejection

Prednisolone
    Dosage: 50 mg, qd, po
    Administration route: Oral
    Indication: Corneal Graft Rejection



Possible Betamethasone side effects / adverse reactions in 62 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-07

Patient: 62 year old male weighing 70.0 kg (154.0 pounds)

Reactions: Vomiting, Pneumonia Aspiration, Refusal of Treatment by Relative, Hydrocephalus, Cerebral Haemorrhage, Gastric Fistula

Adverse event resulted in: hospitalization

Suspect drug(s):
Cyanocobalamin
    Dosage: 3 or 4 times daily, intraocular
    Indication: Asthenopia
    Start date: 2010-10-01
    End date: 2011-03-27

Betamethasone
    Dosage: as needed, transdermal
    Indication: Pustular Psoriasis
    Start date: 2008-10-24
    End date: 2011-03-27

Betamethasone
    Dosage: as needed, transdermal
    Indication: Pustular Psoriasis
    Start date: 2011-03-02
    End date: 2011-03-27

Phenobal (Phenobarbital) (Tablet) (Phenobarbital)
    Dosage: 90 mg (30 mg, 3 in 1 d), per oral
    Administration route: Oral
    Indication: Epilepsy
    Start date: 2008-01-01
    End date: 2011-03-27

Amlodipine Besylate
    Dosage: 5 mg (5 mg, 1 in 1 d), per oral
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-10-29
    End date: 2011-03-27

MAG-LAX (Magnesium Hydroxide, Paraffin, Liquid) (Tablet) (Magnesium HY
    Dosage: 660 mg (330 mg 2 in 1 d), per oral
    Administration route: Oral
    Indication: Constipation
    Start date: 2008-09-01
    End date: 2011-03-27

Ketoprofen
    Dosage: as needed, transdermal
    Indication: Back Pain
    Start date: 2008-06-01
    End date: 2011-03-27

Isosorbide Dinitrate
    Dosage: 40 mg (20 mg, 2 in 1 d), per oral
    Administration route: Oral
    Indication: Angina Pectoris
    Start date: 2008-05-22
    End date: 2011-03-27

Livostin
    Dosage: 3 or 4 times daily, intraocular
    Indication: Conjunctivitis Allergic
    Start date: 2010-10-01
    End date: 2011-03-27

Zoloft
    Dosage: 50 mg (25 mg, 2 in 1 d), per oral
    Administration route: Oral
    Indication: Depression
    Start date: 2008-06-26
    End date: 2011-03-27

Lyrica
    Dosage: 150 mg (75 mg, 2 in 1 d), per oral
    Administration route: Oral
    Indication: Pain
    Start date: 2010-10-25
    End date: 2011-03-27

Loxoprofen Sodium (Loxoprofen Sodium) (Tablet) (Loxoprofen Sodium)
    Dosage: as needed (60 mg), per oral
    Administration route: Oral
    Indication: Pain
    Start date: 2009-05-07
    End date: 2011-03-27

Brotizolam (Brotizolam) (Tablet) (Brotizolam)
    Dosage: 0.25 mg (0.25 mg, 1 in 1 d), per oral
    Administration route: Oral
    Indication: Insomnia
    Start date: 2009-05-13
    End date: 2011-03-27

Olmesartan Medoxomil
    Dosage: 20 mg (20 mg, 1 in 1 d), per oral
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-05-01
    End date: 2011-03-27

Tolterodine Tartrate
    Dosage: 4 mg (4 mg, 1 in 1 d), per oral
    Administration route: Oral
    Indication: Hypertonic Bladder
    Start date: 2010-11-19
    End date: 2011-03-26

Allegra
    Dosage: 120 mg (60 mg, 2 in 1 d), per oral
    Administration route: Oral
    Indication: Pustular Psoriasis
    Start date: 2011-03-02
    End date: 2011-03-27



See index of all Betamethasone side effect reports >>

Drug label data at the top of this Page last updated: 2010-04-01

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