NEWS HIGHLIGHTSMedia Articles Related to Betadine (Povidone-Iodine Ophthalmic)
Accidental Inhalation Of Betadine During Surgery Leads To Rare Complication
Source: Cleft Palate News From Medical News Today [2013.02.25]
A routine step in preparing for cleft palate surgery in a child led to an unusual - but not unprecedented - case of lung inflammation (pneumonitis), according to a report in the The Journal of Craniofacial Surgery. The journal, edited by Mutaz B. Habal, MD, FRCSC, is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health...
Published Studies Related to Betadine (Povidone-Iodine Ophthalmic)
Treatment of Epidemic Keratoconjunctivitis with 2% Povidone-Iodine: A Pilot Study. [2011.09.14]
Abstract Purpose: The purpose of this study was to analyze the outcome of treating epidemic keratoconjunctivitis (EKC) with 2% povidone-iodine (PVP-I) solution. Methods: A prospective, interventional, uncontrolled study was performed in participants diagnosed with EKC...
Preparation of corneal donor eyes comparing 1% versus 5% povidone-iodine. [2011.03]
PURPOSE: To compare the effect of 1% versus 5% polyvinylpyrrolidone-iodine (PVP-I) chemical preparation (prep) of the eye on the recovery of organisms from donor globes before in situ recovery of donor corneal tissue... CONCLUSIONS: This study found that 1% and 5% PVP-I solutions are equally effective for chemical prep of the donor eye. Because PVP-I is known to be toxic to the corneal endothelium and corneal fibroblasts, this study suggests that 1% PVP-I should be the preferred disinfectant for the recovery of corneal donors.
Povidone-iodine: an anti-oedematous agent? [2011.02]
Polyvinylpyrrolidone-iodine (PVP-I) is a well-known antiseptic, widely used in various preparations and concentrations in all surgical fields. It is also used as an irrigant for open wounds and in some centres for irrigating sockets after tooth extraction...
Use of povidone-iodine drop instead of sub-conjunctival injection of dexamethasone and gentamicin combination at the end of phacoemulsification cataract surgery. [2010.04]
To evaluate the use of 5% povidone-iodine drop with subconjunctival injection of dexamethasone and gentamicin combination at the completion of phacoemulsification cataract surgery. This prospective randomized study was conducted at the department of Ophthalmology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh during the period of July, 2005 to June 2006...
Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis. [2010.01.07]
BACKGROUND: Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis may decrease postoperative infections. We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine... CONCLUSIONS: Preoperative cleansing of the patient's skin with chlorhexidine-alcohol is superior to cleansing with povidone-iodine for preventing surgical-site infection after clean-contaminated surgery. (ClinicalTrials.gov number, NCT00290290.) 2010 Massachusetts Medical Society
Clinical Trials Related to Betadine (Povidone-Iodine Ophthalmic)
ChloraPrep Versus Betadine for Elective Knee Replacement Surgery [Recruiting]
This study will enroll patients who will be receiving primary total knee replacements.
Subjects will be randomized into two groups: Betadine surgical scrub preparation and
ChloraPrep preparation prior to total knee replacements.
Study hypothesis: When used as a surgical scrub preparation prior to primary total knee
arthroplasties, ChloraPrep (2% chlorhexadine gluconate and 70% isopropyl alcohol) is
superior to Betadine (10% povidone iodine) in reducing incision site bacterial colony
counts.
Dilute Betadine Lavage in the Prevention of Postoperative Infection [Recruiting]
The purpose of this study is to examine the efficacy of a dilute betadine solution in
reducing infectious complications in revision total knee arthroplasty. The investigators
will enroll patients who are scheduled to undergo a revision total knee arthroplasty.
Patients will be randomized into two groups. The treatment group will receive a dilute
betadine lavage prior to surgical closure for 3 minutes followed by 2000ml of sterile saline
irrigation and the control group will receive the 2000ml sterile saline lavage alone.
Chlorhexidine Versus Betadine in Preventing Colonization of Femoral Nerve Catheters After Total Joint Arthroplasty (TJA) [Not yet recruiting]
Continuous femoral nerve block (CFNB) techniques continue to be increasingly used in the
management of postoperative pain after total knee arthroplasty. Although the risk of full
blown infection with CFNB has been poorly defined, the rate of catheter colonization after
antisepsis with povidone-iodine has been demonstrated to be high (Cuivillion et al. showed
the rate of colonization to be 57% after 48 hours). Recently, several anecdotal case reports
have demonstrated severe infectious complications including psoas abscess and necrotizing
fasciitis associated with continuous nerve block techniques. As the use of CFNB techniques
increase in popularity, infectious complications will undoubtedly become more common.
The American Society of Regional Anesthesia and Pain Medicine recommends the routine use of
antiseptic solutions with an alcohol base for skin disinfection before peripheral regional
techniques due to their penetration of the stratum corneum and their rapid and prolonged
effect. Chlorhexidine(chloraprep) has been proven to be better than povidone iodine solution
for skin preparation before epidural catheter and intravascular device insertion (Kinirons
et al., Ostrander et al., Mimoz et al.,). The goal of this prospective trial therefore is to
determine if an alcoholic solution of 0. 5% chlorhexidine is more effective than an aqueous
solution of 10% povidone-iodine in reducing catheter colonization and reducing skin flora
associated with short term ( 48 hours) postoperative continuous femoral nerve catheter
placement. The investigators will also compare the ability of chloraprep and betadine
disinfection at the time of catheter placement to prevent bacterial contamination of the
continuous femoral catheter.
A Clinical Trial of the Treatment of Fungal Corneal Ulcers With Povidone-Iodine [Recruiting]
The purpose of this study is to determine the effectiveness of 1. 25% povidone-iodine
ophthalmic solution for the treatment of small to medium sized fungal corneal ulcers
compared with an antifungal antibiotic.
Comparative Efficacy of Different Regimens of PVPI 5% Eye Drops Instillation in Reducing Conjunctival Bacterial Flora [Recruiting]
Reports of Suspected Betadine (Povidone-Iodine Ophthalmic) Side Effects
Toxic Anterior Segment Syndrome (37),
Medication Error (20),
Endophthalmitis (8),
Post Procedural Complication (7),
Drug Hypersensitivity (7),
Rash Maculo-Papular (4),
Anaphylactic Shock (3),
Visual Acuity Reduced (3),
Rash Erythematous (3),
Pruritus (2), more >>
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