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Betadine (Povidone-Iodine Ophthalmic) - Summary



Betadine® 5% Sterile Ophthalmic Prep Solution (povidone-iodine ophthalmic solution) (0.5% available iodine)

Povidone-Iodine is a broad-spectrum microbicide compound with iodine.

BETADINE 5% Sterile Ophthalmic Prep Solution for the eye is indicated for prepping of the periocular region (lids, brow, and cheek) and irrigation of the ocular surface (cornea, conjunctiva, and palpebral fornices).

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Media Articles Related to Betadine (Povidone-Iodine Ophthalmic)

Accidental Inhalation Of Betadine During Surgery Leads To Rare Complication
Source: Cleft Palate News From Medical News Today [2013.02.25]
A routine step in preparing for cleft palate surgery in a child led to an unusual - but not unprecedented - case of lung inflammation (pneumonitis), according to a report in the The Journal of...

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Published Studies Related to Betadine (Povidone-Iodine Ophthalmic)

Treatment of Epidemic Keratoconjunctivitis with 2% Povidone-Iodine: A Pilot Study. [2011.09.14]
Abstract Purpose: The purpose of this study was to analyze the outcome of treating epidemic keratoconjunctivitis (EKC) with 2% povidone-iodine (PVP-I) solution. Methods: A prospective, interventional, uncontrolled study was performed in participants diagnosed with EKC...

Preparation of corneal donor eyes comparing 1% versus 5% povidone-iodine. [2011.03]
PURPOSE: To compare the effect of 1% versus 5% polyvinylpyrrolidone-iodine (PVP-I) chemical preparation (prep) of the eye on the recovery of organisms from donor globes before in situ recovery of donor corneal tissue... CONCLUSIONS: This study found that 1% and 5% PVP-I solutions are equally effective for chemical prep of the donor eye. Because PVP-I is known to be toxic to the corneal endothelium and corneal fibroblasts, this study suggests that 1% PVP-I should be the preferred disinfectant for the recovery of corneal donors.

Povidone-iodine: an anti-oedematous agent? [2011.02]
Polyvinylpyrrolidone-iodine (PVP-I) is a well-known antiseptic, widely used in various preparations and concentrations in all surgical fields. It is also used as an irrigant for open wounds and in some centres for irrigating sockets after tooth extraction...

Use of povidone-iodine drop instead of sub-conjunctival injection of dexamethasone and gentamicin combination at the end of phacoemulsification cataract surgery. [2010.04]
To evaluate the use of 5% povidone-iodine drop with subconjunctival injection of dexamethasone and gentamicin combination at the completion of phacoemulsification cataract surgery. This prospective randomized study was conducted at the department of Ophthalmology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh during the period of July, 2005 to June 2006...

Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis. [2010.01.07]
BACKGROUND: Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis may decrease postoperative infections. We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine... CONCLUSIONS: Preoperative cleansing of the patient's skin with chlorhexidine-alcohol is superior to cleansing with povidone-iodine for preventing surgical-site infection after clean-contaminated surgery. (ClinicalTrials.gov number, NCT00290290.) 2010 Massachusetts Medical Society

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Clinical Trials Related to Betadine (Povidone-Iodine Ophthalmic)

ChloraPrep Versus Betadine for Elective Knee Replacement Surgery [Recruiting]
This study will enroll patients who will be receiving primary total knee replacements. Subjects will be randomized into two groups: Betadine surgical scrub preparation and ChloraPrep preparation prior to total knee replacements.

Study hypothesis: When used as a surgical scrub preparation prior to primary total knee arthroplasties, ChloraPrep (2% chlorhexadine gluconate and 70% isopropyl alcohol) is superior to Betadine (10% povidone iodine) in reducing incision site bacterial colony counts.

A Clinical Trial of the Treatment of Fungal Corneal Ulcers With Povidone-Iodine [Recruiting]
The purpose of this study is to determine the effectiveness of 1. 25% povidone-iodine ophthalmic solution for the treatment of small to medium sized fungal corneal ulcers compared with an antifungal antibiotic.

PVP Iodine Effect on Post Debridement Bacteraemia [Not yet recruiting]
The study investigates the effect of supra- and subgingival rinsing of 10% PVP prior to ultrasonic debridement in patients with periodontitis (as compared to rinsing with water) in terms of post treatment bacteraemia.

Study design: Randomized split-mouth (cross-over) study on 20 generally healthy subjects.

A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections [Recruiting]
The purpose of this study is to find out if chlorhexidine gluconate solution is better at reducing the rate of wound infection after cesarean section compared to povidone-iodine.

Study of Povidone Iodine to Reduce Pulmonary Infection in Head Trauma and Cerebral Hemorrhage in Intensive Care Unit [Recruiting]
Head trauma and severe cerebral hemorrhage are major risk factors for development of ventilator-associated pneumonia. In a previous open labelled, single center study the investigators showed that repeated oropharyngeal decontamination with povidone-iodine may be an effective strategy to decrease the prevalence of ventilator-associated pneumonia in patients with head trauma. The present study aims to confirm these results in a multicenter, double blind study including patients suffering from head trauma or cerebral hemorrhage.

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Reports of Suspected Betadine (Povidone-Iodine Ophthalmic) Side Effects

Toxic Anterior Segment Syndrome (37)Medication Error (20)Endophthalmitis (8)Post Procedural Complication (7)Drug Hypersensitivity (7)Rash Maculo-Papular (4)Anaphylactic Shock (3)Visual Acuity Reduced (3)Rash Erythematous (3)Pruritus (2)more >>

Page last updated: 2013-02-25

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