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Benzaclin (Clindamycin Phosphate Topical Gel) - Summary

 
 



BENZACLIN SUMMARY

BenzaClin® Topical Gel contains clindamycin phosphate, (7(S)-chloro-7-deoxylincomycin-2-phosphate). Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.

BenzaClin Topical Gel is indicated for the topical treatment of acne vulgaris.


See all Benzaclin indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Benzaclin (Clindamycin Topical)

Health Tip: Four Common Types Of Acne
Source: MedicineNet Acne Specialty [2017.09.20]
Title: Health Tip: Four Common Types Of Acne
Category: Health News
Created: 9/20/2017 12:00:00 AM
Last Editorial Review: 9/20/2017 12:00:00 AM

Acne (Pimples) Quiz: Test Your Medical IQ
Source: MedicineNet Acne Specialty [2017.09.19]
Title: Acne (Pimples) Quiz: Test Your Medical IQ
Category: MedicineNet Quiz
Created: 2/28/2011 4:15:00 PM
Last Editorial Review: 9/19/2017 5:39:39 PM

Skin Quiz: Acne, Dry Skin, Dandruff & More
Source: MedicineNet Acne Specialty [2017.09.19]
Title: Skin Quiz: Acne, Dry Skin, Dandruff & More
Category: MedicineNet Quiz
Created: 10/7/2010 12:00:00 AM
Last Editorial Review: 9/19/2017 5:01:04 PM

Health Tip: Can't Clear Your Acne?
Source: MedicineNet Acne Specialty [2017.08.02]
Title: Health Tip: Can't Clear Your Acne?
Category: Health News
Created: 8/2/2017 12:00:00 AM
Last Editorial Review: 8/2/2017 12:00:00 AM

Acne 101: Types, Best Treatments, Medication, Cystic Acne
Source: MedicineNet isotretinoin Specialty [2017.05.04]
Title: Acne 101: Types, Best Treatments, Medication, Cystic Acne
Category: Slideshows
Created: 10/16/2014 12:00:00 AM
Last Editorial Review: 5/4/2017 12:00:00 AM

more news >>

Published Studies Related to Benzaclin (Clindamycin Topical)

Efficacy of clindamycin in reducing pain following tonsillectomy in adults: a double-blind, randomised trial. [2013]
reducing throat pain after tonsillectomy in adult patients... CONCLUSION: Topical clindamycin was not demonstrated to be more effective than

Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne vulgaris. [2013]
Nicotinamide and clindamycin gels are two popular topical medications for acne vulgaris... Skin type is a significant factor in choosing between topical nicotinamide and clindamycin in patients with acne vulgaris.

Fitzpatrick skin types and clindamycin phosphate 1.2%/benzoyl peroxide gel: efficacy and tolerability of treatment in moderate to severe acne. [2012]
efficacy of acne medications in skin of color... CONCLUSIONS: Acne subjects with Fitzpatrick skin types IV-VI were not found to be

Treatment of moderate to severe acne vulgaris in a Hispanic population: a post-hoc analysis of efficacy and tolerability of clindamycin phosphate 1.2%/benzoyl peroxide 2.5% gel. [2012]
in Hispanics... CONCLUSIONS: Overall efficacy and tolerability with clindamycin phosphate

A randomized, double-blind, placebo-controlled, pilot study to assess the efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for the treatment of acne rosacea over 12 weeks. [2012]
rosacea after 12 weeks of usage... CONCLUSIONS: A combination gel of clindamycin phosphate 1.2% and tretinoin 0.025%

more studies >>

Clinical Trials Related to Benzaclin (Clindamycin Topical)

Evaluation of Quality of Life, Efficacy, and Tolerance of Duac� Gel Compared to Differin� Gel in the Treatment of Acne [Completed]
The objectives of this clinical trial are to compare the quality of life of the subjects, the efficacy and the tolerance of Duac® Gel (gel formulation with a combination of clindamycin phosphate [equivalent to 1% clindamycin] and 5% benzoyl peroxide), applied once daily, against Differin® Gel (gel with 0. 1% adapalene), used once daily, in the treatment of mild to moderate acne vulgaris.

Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne Vulgaris [Completed]
The purpose of this study is to compare the effectiveness of two marketed products in subjects with facial acne vulgaris

To Compare the Efficacy and Safety of Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel of CHL Versus DUAC® Gel [Recruiting]
This is an Randomized, Double-blind, Multicentric, Parallel-group, Active and Placebo Controlled, Three Arm Clinical Study. The main objective is to evaluate bioequivalence of Test formulation (Clindamycin Phosphate 1. 2%/Benzoyl peroxide 5% gel) of Cadila Healthcare with Reference formulation (DUAC® Gel of Stiefel Laboratories)in the ratio of 2: 2:1 of Test drug, Reference drug and Placebo respectively. Total study duration will be for a period of 78 days which includes treatment duration of 77 days. 850 subjects will be enrolled (randomized)as per the inclusion and exclusion criteria mentioned in the protocol.

A Study Comparing Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel to Duac� Topical Gel in the Treatment of Acne Vulgaris [Completed]
The objective of this study is to compare the relative efficacy and safety of the test formulation Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Taro Pharmaceuticals Inc.) to the marketed formulation Duac® Topical Gel (Clindamycin 1%/Benzoyl Peroxide 5%) (Stiefel) in the treatment of the inflamed lesions of acne vulgaris. Both the test and reference formulations will also be compared to a placebo formulation to test for superiority.

Study Comparing Clindamycin Phosphate and Benzoyl Peroxide Gel to Acanya® Gel and Both to a Vehicle Control in the Treatment of Acne Vulgaris [Completed]
The objective of this study is to compare the safety and efficacy profiles of Taro Pharmaceutical Inc.'s Clindamycin Phosphate and Benzoyl Peroxide Gel 1. 2%/2. 5% to Acanya® (Clindamycin Phosphate and Benzoyl Peroxide) Gel, 1. 2%/2. 5% and to demonstrate the superior efficacy of the two active formulations over that of the vehicle in the treatment of acne vulgaris.

more trials >>

Reports of Suspected Benzaclin (Clindamycin Topical) Side Effects

Colitis Ulcerative (4)Gastrointestinal Haemorrhage (2)Drug Ineffective (2)Loss of Consciousness (2)Oesophageal Ulcer (2)Anaemia (2)Odynophagia (2)Small Intestinal Obstruction (2)Diarrhoea (2)Leukocytosis (2)more >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 3 ratings/reviews, Benzaclin has an overall score of 8. The effectiveness score is 8.67 and the side effect score is 7.33. The scores are on ten point scale: 10 - best, 1 - worst.
 

Benzaclin review by 28 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   dont remember (dosage frequency: twice a day) for the period of 1 year
Other conditions:   acne scarring
Other drugs taken:   nothing
  
Reported Results
Benefits:   None
Side effects:   None
Comments:   None

 

Benzaclin review by 40 year old female patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   topical application (dosage frequency: once daily) for the period of several years
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   This has helped reduce my cystic acne that forms on my chin area. Nothing has helped previously.I had tried OTC products including Proactiv as well as RX differin. The cysts still occur occasionally but with far less frequency.
Side effects:   dryness
Comments:   Applied daily in the evening. At first sign of a cyst forming I usually apply it twice daily.

 

Benzaclin review by 40 year old female patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   topical application (dosage frequency: once daily) for the period of several years
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   This has helped reduce my cystic acne that forms on my chin area. Nothing has helped previously.I had tried OTC products including Proactiv as well as RX differin. The cysts still occur occasionally but with far less frequency.
Side effects:   dryness
Comments:   Applied daily in the evening. At first sign of a cyst forming I usually apply it twice daily.

See all Benzaclin reviews / ratings >>

Page last updated: 2017-09-20

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