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Benzaclin (Clindamycin Phosphate Topical Gel) - Summary

 
 



BENZACLIN SUMMARY

BenzaClin® Topical Gel
(clindamycin - benzoyl peroxide gel)

BenzaClin® Topical Gel contains clindamycin phosphate, (7(S)-chloro-7-deoxylincomycin-2-phosphate). Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.

BenzaClin Topical Gel is indicated for the topical treatment of acne vulgaris.


See all Benzaclin indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Benzaclin (Clindamycin Topical)

Some Acne Products Can Trigger Severe Allergic Reactions: FDA
Source: MedicineNet Acne Specialty [2014.06.26]
Title: Some Acne Products Can Trigger Severe Allergic Reactions: FDA
Category: Health News
Created: 6/25/2014 4:35:00 PM
Last Editorial Review: 6/26/2014 12:00:00 AM

New Approaches to Acne Treatment
Source: MedicineNet Acne Specialty [2014.06.10]
Title: New Approaches to Acne Treatment
Category: Health News
Created: 6/9/2014 12:35:00 PM
Last Editorial Review: 6/10/2014 12:00:00 AM

Clear Skin Pictures Slideshow: Helping Your Teen With Acne
Source: MedicineNet Boils Specialty [2013.11.07]
Title: Clear Skin Pictures Slideshow: Helping Your Teen With Acne
Category: Slideshows
Created: 1/20/2010 3:54:00 PM
Last Editorial Review: 11/7/2013 12:00:00 AM

Acne (Pimples)
Source: MedicineNet Boils Specialty [2013.08.13]
Title: Acne (Pimples)
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 8/13/2013 12:00:00 AM

Pediatricians Endorse New Acne Treatment Guidelines
Source: MedicineNet isotretinoin Specialty [2013.05.06]
Title: Pediatricians Endorse New Acne Treatment Guidelines
Category: Health News
Created: 5/6/2013 10:35:00 AM
Last Editorial Review: 5/6/2013 12:00:00 AM

more news >>

Published Studies Related to Benzaclin (Clindamycin Topical)

Fitzpatrick skin types and clindamycin phosphate 1.2%/benzoyl peroxide gel: efficacy and tolerability of treatment in moderate to severe acne. [2012]
efficacy of acne medications in skin of color... CONCLUSIONS: Acne subjects with Fitzpatrick skin types IV-VI were not found to be

Treatment of moderate to severe acne vulgaris in a Hispanic population: a post-hoc analysis of efficacy and tolerability of clindamycin phosphate 1.2%/benzoyl peroxide 2.5% gel. [2012]
in Hispanics... CONCLUSIONS: Overall efficacy and tolerability with clindamycin phosphate

A randomized, double-blind, placebo-controlled, pilot study to assess the efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for the treatment of acne rosacea over 12 weeks. [2012]
rosacea after 12 weeks of usage... CONCLUSIONS: A combination gel of clindamycin phosphate 1.2% and tretinoin 0.025%

Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: A randomized controlled trial. [2011.11]
BACKGROUND: Topical therapy with comedolytics and antibiotics are often advocated for mild and moderate severity acne vulgaris. Nadifloxacin, a new fluoroquinolone with anti-Propionibacterium acnes activity and additional anti-inflammatory activity, is approved for use in acne. This randomized controlled assessor blind trial compared the clinical effectiveness and safety of eight weeks therapy of nadifloxacin 1% versus clindamycin 1% as add-on therapy to benzoyl peroxide (2.5%) in mild to moderate grade acne... CONCLUSIONS: Topical nadifloxacin, a new fluoroquinolone is effective, tolerable, and safe for mild o moderate facial acne. Its clinical effectiveness is comparable to clindamycin when used as add-on therapy to benzoyl peroxide.

Efficacy of topical combination of benzoyl peroxide 5% and clindamycin 1% for the treatment of progressive macular hypomelanosis: a randomized, doubleblind, placebo-controlled trial. [2011.02]
BACKGROUND: Progressive macular hypomelanosis is a dermatosis without definite etiology. There is no consensus or first-line therapy in the treatment of progressive macular hypomelanosis, and the treatment options used are very little effective. OBJECTIVE: To evaluate the therapeutic efficacy of the topical combination of benzoyl peroxide 5% and clindamycin 1% associated with sun exposure for the treatment of progressive macular hypomelanosis... CONCLUSION: The topical combination of benzoyl peroxide 5% and clindamycin 1% is effective in the treatment of progressive macular hypomelanosis.

more studies >>

Clinical Trials Related to Benzaclin (Clindamycin Topical)

A Study Comparing Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel to Duac� Topical Gel in the Treatment of Acne Vulgaris [Recruiting]
The objective of this study is to compare the relative efficacy and safety of the test formulation Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Taro Pharmaceuticals Inc.) to the marketed formulation Duac® Topical Gel (Clindamycin 1%/Benzoyl Peroxide 5%) (Stiefel) in the treatment of the inflamed lesions of acne vulgaris. Both the test and reference formulations will also be compared to a placebo formulation to test for superiority.

Study Comparing Clindamycin Phosphate and Benzoyl Peroxide Gel to Acanya� Gel and Both to a Vehicle Control in the Treatment of Acne Vulgaris [Recruiting]
The objective of this study is to compare the safety and efficacy profiles of Taro Pharmaceutical Inc.'s Clindamycin Phosphate and Benzoyl Peroxide Gel 1. 2%/2. 5% to Acanya® (Clindamycin Phosphate and Benzoyl Peroxide) Gel, 1. 2%/2. 5% and to demonstrate the superior efficacy of the two active formulations over that of the vehicle in the treatment of acne vulgaris.

Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne Vulgaris [Recruiting]
The purpose of this study is to compare the effectiveness of two marketed products in subjects with facial acne vulgaris

Comparing OTC Acne Treatment to Prescription Regimen [Recruiting]
This research is being done to find out the safety and efficacy of two acne creams, Effaclar and Benzaclin when used twice daily with a topical retinoid. Effaclar and Benzaclin are FDA approved for the treatment of acne.

Combination Therapy With Differin® Gel 0.3% and Duac® (Clindamycin/Benzoyl Peroxide Gel) in Subjects With Acne Vulgaris [Recruiting]
This study is to determine the efficacy and safety of 12 week treatment with Differin® Gel 0. 3% applied in the evening, in combination with Duac® (Clindamycin/Benzoyl Peroxide Gel) applied in the morning, in Subjects with Acne vulgaris.

more trials >>

Reports of Suspected Benzaclin (Clindamycin Topical) Side Effects

Colitis Ulcerative (4)Gastrointestinal Haemorrhage (2)Drug Ineffective (2)Loss of Consciousness (2)Oesophageal Ulcer (2)Anaemia (2)Odynophagia (2)Small Intestinal Obstruction (2)Diarrhoea (2)Leukocytosis (2)more >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 3 ratings/reviews, Benzaclin has an overall score of 8. The effectiveness score is 8.67 and the side effect score is 7.33. The scores are on ten point scale: 10 - best, 1 - worst.
 

Benzaclin review by 28 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   dont remember (dosage frequency: twice a day) for the period of 1 year
Other conditions:   acne scarring
Other drugs taken:   nothing
  
Reported Results
Benefits:   None
Side effects:   None
Comments:   None

 

Benzaclin review by 40 year old female patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   topical application (dosage frequency: once daily) for the period of several years
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   This has helped reduce my cystic acne that forms on my chin area. Nothing has helped previously.I had tried OTC products including Proactiv as well as RX differin. The cysts still occur occasionally but with far less frequency.
Side effects:   dryness
Comments:   Applied daily in the evening. At first sign of a cyst forming I usually apply it twice daily.

 

Benzaclin review by 40 year old female patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   acne
Dosage & duration:   topical application (dosage frequency: once daily) for the period of several years
Other conditions:   none
Other drugs taken:   none
  
Reported Results
Benefits:   This has helped reduce my cystic acne that forms on my chin area. Nothing has helped previously.I had tried OTC products including Proactiv as well as RX differin. The cysts still occur occasionally but with far less frequency.
Side effects:   dryness
Comments:   Applied daily in the evening. At first sign of a cyst forming I usually apply it twice daily.

See all Benzaclin reviews / ratings >>

Page last updated: 2014-06-26

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