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Bentyl (Dicyclomine Hydrochloride) - Summary

 



BENTYL SUMMARY

BENTYL®
(dicyclomine hydrochloride USP)

BENTYL is an antispasmodic and anticholinergic (antimuscarinic) agent.

BENTYL is indicated for the treatment of functional bowel/irritable bowel syndrome.


See all indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Bentyl (Dicyclomine)

Bacterial Phylotype Alterations In Irritable Bowel Syndrome
Source: Irritable-Bowel Syndrome News From Medical News Today [2010.01.18]
Irritable bowel syndrome (IBS) is a common gastrointestinal functional disorder that can greatly affect the patient's well being. Multiple interacting mechanisms, including alterations in the intestinal microbiota, are suspected to lie behind IBS aetiology. A research article published on December 21, 2009 in the World Journal of Gastroenterology addresses this problem...

St. John's Wort Doesn't Ease Irritable Bowel Syndrome (HealthDay)
Source: Y! Health Digestive Health News [2010.01.07]
HealthDay - THURSDAY, Jan. 7 (HealthDay News) -- The popular herbal supplement St. John's wort does not appear to relieve the pain and discomfort that accompanies irritable bowel syndrome (IBS), new research suggests.

Irritable Bowel Syndrome Does Not Respond To St. John's Wort
Source: Irritable-Bowel Syndrome News From Medical News Today [2010.01.06]
A Mayo Clinic research study published in the January issue of the American Journal of Gastroenterology finds that St. John's wort is not an effective treatment for irritable bowel syndrome (IBS). While antidepressants are frequently used to treat IBS, to date, no study has examined the success of using the herbal supplement St. John's wort in treating IBS...

St. John's Wort Not Helpful Treatment For Irritable Bowel Syndrome
Source: Irritable-Bowel Syndrome News From Medical News Today [2010.01.05]
A Mayo Clinic research study published in the January issue of The American Journal of Gastroenterology finds that St. John's wort is not an effective treatment for irritable bowel syndrome (IBS). While antidepressants are frequently used to treat IBS, to date, no study has examined the success of using the herbal supplement St. John's wort in treating IBS...

IBS: Dealing With Irritable Bowel Syndrome at Work
Source: MedicineNet Abdominal Pain Specialty [2009.12.16]
Title: IBS: Dealing With Irritable Bowel Syndrome at Work
Category: Health Facts
Created: 12/16/2009 5:58:00 PM
Last Editorial Review: 12/16/2009 5:58:44 PM

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Published Studies Related to Bentyl (Dicyclomine)

Dose effect of dicyclomine on the reduction of peristaltic artifacts on MRI of the abdomen. [1999.07]
BACKGROUND: It has been demonstrated that oral administration of dicyclomine significantly reduces the noise associated with the movement of the gastrointestinal tract in abdominal magnetic resonance (MR) images. Our objective was to determine the efficacy and security of two different doses of oral dicyclomine for the reduction of the gastrointestinal noise in abdominal MR imaging... CONCLUSION: Oral dicyclomine is effective and safe for the reduction of peristaltic artifacts on abdominal MR imaging. The dose of 20 mg presents an efficacy similar to that of 80 mg, with a probably lower incidence of adverse reactions.

Dietary modifications versus dicyclomine hydrochloride in the treatment of severe infantile colics. [1994.02]
This study examined 120 infants, aged 3-12 weeks, with severe colics and compared the results of a specific hypoallergenic diet (group A) with those of pharmacological treatment (group B). Non-breast-fed group A infants received soy milk and if unresponsive, hydrolyzed milk formulas; mothers of breast-fed infants received a diet without cow's milk, eggs or fish...

Dicyclomine, an M1 muscarinic antagonist, reduces biomarker levels, but not neuronal degeneration, in fluid percussion brain injury. [2008.11]
Recent studies indicate that alphaII-spectrin breakdown products (SBDPs) have utility as biological markers of traumatic brain injury (TBI). However, the utility of SBDP biomarkers for detecting effects of therapeutic interventions has not been explored...

Dicyclomine for medical management of persistent anal fissure with associated spasm of the internal sphincter. [1992.11]
The case of a 43-year-old woman with persistent anal fissure responsive to dicyclomine is described... Surgery was avoided.

Antenatal exposure to doxylamine succinate and dicyclomine hydrochloride (Benedectin) in relation to congenital malformations, perinatal mortality rate, birth weight, and intelligence quotient score. [1977.07.01]
PIP: The effects of doxylamine succinate (DAS) and dicylomin hydrochloride (DHC), each of which is contained in the drug Bendectin, administration during pregnancy on offspring was investigated in a prospective cohort study of 50,282 women and their offspring.

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PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 1 ratings/reviews, Bentyl has an overall score of 7. The effectiveness score is 8 and the side effect score is 6. The scores are on ten point scale: 10 - best, 1 - worst.
 

Bentyl review by care giver of 54 year old male patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   Moderate Side Effects
  
Treatment Info
Condition / reason:   Diaheria assc. w/ chemo
Dosage & duration:   5mg taken 2/day for the period of 4 days
Other conditions:   mouth sores
Other drugs taken:   flucanazole, immodium, ativan
  
Reported Results
Benefits:   controlled loose stool and fluid loss due to chemo; nausea control; control of mouth thrush, sores. The Bentil in particular worked much better than immodium for diarhea control and fluid retention. It also stopped colon muscle spasm.
Side effects:   dizziness, fatigue, loss of appetite
Comments:   benil taken 2x a day to control diarhea; flucanzole 1x a day for thrush; rest of medications for nausea

See all reviews / ratings >>

Page last updated: 2010-01-18

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