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Benicar (Olmesartan Medoxomil) - Summary

 

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USE IN PREGNANCY

When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. When pregnancy is detected, BENICAR® should be discontinued as soon as possible. See WARNINGS, Fetal/Neonatal Morbidity and Mortality.

 

BENICAR SUMMARY

BENICAR® Tablets
(Olmesartan Medoxomil)

BENICAR® (olmesartan medoxomil), a prodrug, is hydrolyzed to olmesartan during absorption from the gastrointestinal tract. Olmesartan is a selective AT1 subtype angiotensin II receptor antagonist.

BENICAR® is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.

BENICAR NEWS HIGHLIGHTS

Media Articles Related to Benicar (Olmesartan)

Pseudotumor Cerebri (Idiopathic Intracranial Hypertension)
Source: MedicineNet Brain Tumor Specialty [2008.09.30]

Study Finds Antioxidant Deficiency Linked To Pulmonary Hypertension
Source: Hypertension News From Medical News Today [2008.09.24]

Vitamin C Might Help Lower Hypertension
Source: MedicineNet High Blood Pressure Specialty [2008.09.22]

Using Honeybee Venom Toxin To Develop A New Tool For Studying Hypertension
Source: Hypertension News From Medical News Today [2008.09.19]

After Stroke, TPA Therapy OK Even For Those With Hypertension
Source: Hypertension News From Medical News Today [2008.09.09]

more>>

Published Studies Related to Benicar (Olmesartan)

Effect of delapril/manidipine vs olmesartan/ hydrochlorothiazide combination on insulin sensitivity and fibrinogen in obese hypertensive patients. [2008]

Comparison of increasing doses of olmesartan medoxomil, losartan potassium, and valsartan in patients with essential hypertension. [2007.03]

Dose-response characteristics of olmesartan medoxomil and other angiotensin receptor antagonists. [2007]

Olmesartan reducing incidence of endstage renal disease in diabetic nephropathy trial (ORIENT): rationale and study design. [2006.09]

Hydrochlorothiazide added to valsartan is more effective than when added to olmesartan in reducing blood pressure in moderately hypertensive patients inadequately controlled by monotherapy. [2006.09]

more>>

Clinical Trials Related to Benicar (Olmesartan)

Olmesartan in Essential Hypertension [Completed]

An Examination of the Safety and Blood Pressure Lowering Effect of Increasing Doses of Benicar® and Benicar® HCT in Patients With Hypertension [Completed]

Fed Study of Olmesartan Medoxomil Tablets 40 mg and Benicar® Tablets 40 mg [Completed]

Fasting Study of Olmesartan Medoxomil Tablets 40 mg and Benicar® Tablets 40 mg [Completed]

Olmesartan and an Add-on Treatment in Patients With Mild to Moderate Hypertension [Completed]

more>>

Page last updated: 2008-09-30

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