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Benefix (Coagulation Factor IX (Recombinant)) - Drug Interactions, Contraindications, Overdosage, etc



BENEFIX drug label information in our database does not contain a dedicated section on drug interactions. Please check subsections of WARNINGS AND PRECAUTIONS as well as other sources.


Because BeneFIX® , Coagulation Factor IX (Recombinant), is produced in a Chinese hamster ovary cell line, it may be contraindicated in patients with a known history of hypersensitivity to hamster protein.


  1. Lusher JM. Thrombogenicity associated with factor IX complex concentrates. Semin Hematol. 1991;28(3 Suppl. 6):3-5.
  2. Shapiro AD, Ragni MV, Lusher JM, et al. Safety and efficacy of monoclonal antibody purified factor IX concentrate in previously untreated patients with hemophilia B. Thromb Haemost. 1996;75(1):30-35.
  3. Roberts HR, Eberst ME. Current management of hemophilia B. Hematol Oncol Clin North Am. 1993;7(6):1269-1280.


Manufactured by:

Wyeth Pharmaceuticals Inc.

Philadelphia, PA 19101

US Govt. License No. 3

Imported and Distributed in Canada by:

Wyeth Canada

Montreal, Canada



Rev 07/04

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