Bactroban (Mupirocin Calcium Topical) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

In 2 randomized, double-blind, double-dummy trials, 339 patients were treated with topical BACTROBAN CREAM plus oral placebo. Adverse events thought to be possibly or probably drug-related occurred in 28 (8.3%) patients. The incidence of those events that were reported in at least 1% of patients enrolled in these trials were: Headache (1.7%), rash, and nausea (1.1% each).

Other adverse events thought to be possibly or probably drug-related which occurred in less than 1% of patients were: Abdominal pain, burning at application site, cellulitis, dermatitis, dizziness, pruritus, secondary wound infection, and ulcerative stomatitis.

In a supportive study in the treatment of secondarily infected eczema, 82 patients were treated with BACTROBAN CREAM. The incidence of adverse events thought to be possibly or probably drug-related was as follows: Nausea (4.9%), headache, and burning at application site (3.6% each), pruritus (2.4%) and 1 report each of abdominal pain, bleeding secondary to eczema, pain secondary to eczema, hives, dry skin, and rash.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO BACTROBAN

Possible Bactroban side effects / adverse reactions in 54 year old male

Reported by a consumer/non-health professional from United Kingdom on 2007-01-08

Patient: 54 year old male

Reactions: Toxic Epidermal Necrolysis

Suspect drug(s):
Amoxicillin
    Dosage: 1g three times per day
    Indication: Drug USE FOR Unknown Indication

Actrapid
    Indication: Drug USE FOR Unknown Indication

Alfentanil
    Indication: Drug USE FOR Unknown Indication

Aquasept
    Indication: Drug USE FOR Unknown Indication

Bactroban
    Indication: Drug USE FOR Unknown Indication

Calcium Chloride
    Indication: Drug USE FOR Unknown Indication

Calcium Gluconate
    Indication: Drug USE FOR Unknown Indication

Ceftriaxone
    Indication: Drug USE FOR Unknown Indication

Clexane
    Dosage: 20mg per day
    Indication: Drug USE FOR Unknown Indication

Dobutamine HCL
    Indication: Drug USE FOR Unknown Indication

Fluconazole
    Dosage: 200mg per day
    Indication: Drug USE FOR Unknown Indication

Fragmin
    Dosage: 2500iu per day
    Indication: Drug USE FOR Unknown Indication

Furosemide
    Dosage: 20mg twice per day
    Indication: Drug USE FOR Unknown Indication

Furosemide
    Dosage: 20mg per day
    Administration route: Oral

Hydrocortisone
    Dosage: 100mg single dose
    Indication: Drug USE FOR Unknown Indication

Lactulose
    Indication: Drug USE FOR Unknown Indication

Lansoprazole
    Indication: Drug USE FOR Unknown Indication

Lorazepam
    Indication: Drug USE FOR Unknown Indication

Magnesium Sulfate
    Indication: Drug USE FOR Unknown Indication

Noradrenaline
    Indication: Drug USE FOR Unknown Indication

Omeprazole
    Indication: Drug USE FOR Unknown Indication

Acetaminophen
    Indication: Drug USE FOR Unknown Indication

Piriton
    Dosage: 10mg four times per day
    Indication: Drug USE FOR Unknown Indication

Potassium Chloride
    Indication: Drug USE FOR Unknown Indication

Potassium Phosphates
    Indication: Drug USE FOR Unknown Indication

Propofol
    Indication: Drug USE FOR Unknown Indication

Ventolin
    Indication: Drug USE FOR Unknown Indication

Sando-K
    Indication: Drug USE FOR Unknown Indication

Silver Sulphadiazine
    Administration route: Topical
    Indication: Drug USE FOR Unknown Indication

Simvastatin
    Dosage: 40mg per day
    Indication: Drug USE FOR Unknown Indication

Sodium Bicarbonate
    Indication: Drug USE FOR Unknown Indication

Sodium Chloride 0.9%
    Indication: Drug USE FOR Unknown Indication

Thiamin
    Dosage: 100mg per day
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Tinzaparin
    Dosage: 3500mcl per day
    Indication: Drug USE FOR Unknown Indication

Vitamin K
    Indication: Drug USE FOR Unknown Indication

Other drugs received by patient: Amoxicillin; Aspirin; Atrovent; Ciprofloxacin; Amoxicillin + Clavulanate Potassium; Erythromycin; Metoclopramide; Midodrine; Pantoprazole Sodium; Piperacillin and Tazobactam; Vancomycin; Zopiclone

Possible Bactroban side effects / adverse reactions in 54 year old male

Reported by a consumer/non-health professional from United Kingdom on 2007-01-09

Patient: 54 year old male

Reactions: Toxic Epidermal Necrolysis

Suspect drug(s):
Rocephin
    Indication: Drug USE FOR Unknown Indication

Actrapid
    Indication: Drug USE FOR Unknown Indication

Vitamin K
    Indication: Drug USE FOR Unknown Indication

Tinzaparin
    Indication: Drug USE FOR Unknown Indication

Thiamin
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Sodium Chloride
    Indication: Drug USE FOR Unknown Indication

Sodium Bicarbonate
    Indication: Drug USE FOR Unknown Indication

Simvastatin
    Indication: Drug USE FOR Unknown Indication

Silver Sulphadiazine
    Administration route: Topical
    Indication: Drug USE FOR Unknown Indication

Sando-K
    Indication: Drug USE FOR Unknown Indication

Ventolin
    Indication: Drug USE FOR Unknown Indication

Propofol
    Indication: Drug USE FOR Unknown Indication

Potassium Phosphates
    Indication: Drug USE FOR Unknown Indication

Potassium Chloride
    Indication: Drug USE FOR Unknown Indication

Piriton
    Indication: Drug USE FOR Unknown Indication

Acetaminophen
    Indication: Drug USE FOR Unknown Indication

Omeprazole
    Indication: Drug USE FOR Unknown Indication

Noradrenaline
    Indication: Drug USE FOR Unknown Indication

Magnesium Sulfate
    Indication: Drug USE FOR Unknown Indication

Lorazepam
    Indication: Drug USE FOR Unknown Indication

Lansoprazole
    Indication: Drug USE FOR Unknown Indication

Lactulose
    Indication: Drug USE FOR Unknown Indication

Hydrocortisone
    Indication: Drug USE FOR Unknown Indication

Furosemide
    Administration route: Oral
    Indication: Drug USE FOR Unknown Indication

Furosemide

Fragmin
    Indication: Drug USE FOR Unknown Indication

Fluconazole
    Indication: Drug USE FOR Unknown Indication

Dobutamine HCL
    Indication: Drug USE FOR Unknown Indication

Clexane
    Indication: Drug USE FOR Unknown Indication

Calcium Gluconate
    Indication: Drug USE FOR Unknown Indication

Calcium Chloride
    Indication: Drug USE FOR Unknown Indication

Bactroban
    Indication: Drug USE FOR Unknown Indication

Aquasept
    Indication: Drug USE FOR Unknown Indication

Amoxicillin
    Indication: Drug USE FOR Unknown Indication

Alfentanil
    Indication: Drug USE FOR Unknown Indication

Other drugs received by patient: Amoxicillin; Aspirin; Atrovent; Ciprofloxacin; Amoxicillin + Clavulanate Potassium; Erythromycin; Metoclopramide; Midodrine; Pantoprazole Sodium; Tazocin; Vancomycin; Zopiclone

Possible Bactroban side effects / adverse reactions in 54 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2007-01-10

Patient: 54 year old male

Reactions: Toxic Epidermal Necrolysis

Suspect drug(s):
Acetaminophen

Amoxicillin

Furosemide

Furosemide
    Administration route: Oral

Hydrocortisone

Potassium Chloride

Ventolin

Silver Sulfadiazine
    Administration route: Topical

Actrapid

Alfentanil

Aquasept

Bactroban

Calcium Chloride

Calcium Gluconate

Ceftriaxone

Clexane

Dobutamine HCL

Fluconazole

Fragmin

Lactulose

Lansoprazole

Lorazepam

Magnesium Sulfate

Noradrenaline

Omeprazole

Piriton

Potassium Phosphates

Propofol

Sando-K

Simvastatin

Sodium Bicarbonate

Sodium Chloride

Thiamin
    Administration route: Oral

Tinzaparin

Vitamin K

Other drugs received by patient: Aspirin; Atrovent; Ciprofloxacin; Amoxicillin + Clavulanate Potassium; Erythromycin; Metoclopramide; Midodrine HCL; Pantoprazole Sodium; Tazocin; Vancomycin; Zopiclone; Amoxicillin