Media Articles Related to Azelex (Azelaic Acid Topical)
Surprising link discovered between chloracne and a molecule that protects cells against stress
Source: Dermatology News From Medical News Today [2014.02.10]
ETH-Zurich researchers have discovered a new, surprising link between chloracne and a molecule that protects cells against stress: if Nrf2 gets out of control, disfiguring cysts form on the skin.The images were seen all over the world and stuck in the minds of many: in the autumn of 2004, former President of the Ukraine, Viktor Yushchenko, was poisoned with a high dose of dioxin.
Treating autoimmune and transplant patients with the vitamin a used in acne medicines
Source: Transplants / Organ Donations News From Medical News Today [2014.02.03]
The same form of Vitamin A used by teenagers to combat acne might offer benefits that are more than skin deep. That's because an international team of researchers have found that it may also help keep the immune system under control for people with autoimmune disorders or those who have received transplants. This finding was published in the February 2014 issue of the Journal of Leukocyte Biology.
Health Tip: Taming Acne
Source: MedicineNet Acne Specialty [2014.01.10]
Title: Health Tip: Taming Acne
Category: Health News
Created: 1/10/2014 7:35:00 AM
Last Editorial Review: 1/10/2014 12:00:00 AM
Acne Pictures Slideshow: Causes, Solutions and Treatments for Adults
Source: MedicineNet Acne Specialty [2013.11.21]
Title: Acne Pictures Slideshow: Causes, Solutions and Treatments for Adults
Created: 9/15/2011 3:45:00 PM
Last Editorial Review: 11/21/2013 12:00:00 AM
Clear Skin Pictures Slideshow: Helping Your Teen With Acne
Source: MedicineNet Boils Specialty [2013.11.07]
Title: Clear Skin Pictures Slideshow: Helping Your Teen With Acne
Created: 1/20/2010 3:54:00 PM
Last Editorial Review: 11/7/2013 12:00:00 AM
Published Studies Related to Azelex (Azelaic Acid Topical)
Combination of azelaic acid 5% and clindamycin 2% for the treatment of acne
vulgaris... CONCLUSION: The profound reduction in lesion count and ASI by
Efficacy of 15% azelaic acid in psoriasis vulgaris: a randomized, controlled clinical trial. [2010.08]
BACKGROUND: Psoriasis is a common disorder affecting 1-3 percent of the general global population...
Efficacy of topical azelaic acid (AzA) gel 15% plus oral doxycycline 40 mg versus metronidazole gel 1% plus oral doxycycline 40 mg in mild-to-moderate papulopustular rosacea. [2010.06]
Rosacea is a leading reason why people seek the care of a dermatologist, accounting for nearly 7 million office visits annually. Pharmacologic treatments include both topical and oral medications, which are increasingly being used in combination, especially at the outset of therapy... These findings warrant further investigation in a sufficiently powered study.
Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. [2010.05]
INTRODUCTION: Acne vulgaris is a common problem, particularly among adolescents, which is usually resistant to monotherapy. We evaluated the efficacy and safety of a combination of azelaic acid (AA) 5% and erythromycin 2% gel (AzE) compared with AA 20% or erythromycin 2% gels in facial acne vulgaris... CONCLUSIONS: The combination of AA 5% and erythromycin 2% produced more potent therapeutic effects in comparison with erythromycin 2% or AA 20% alone, and with fewer side effects.
A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy. [2009.07]
This two-phase, multicenter study was undertaken to examine the safety and efficacy of combination therapy with oral doxycycline and topical azelaic acid (AzA) 15% gel in moderate-to-severe papulopustular rosacea and to determine the effect of subsequent maintenance monotherapy with AzA 15% gel alone...
Clinical Trials Related to Azelex (Azelaic Acid Topical)
Study for Long-term Treatment of Acne Vulgaris With Skinoren Versus Differin [Recruiting]
The purpose of this study is to assess the effect of Skinoren® 15% gel compared to no
therapy on the maintenance of clinical therapy success in subjects with mild to moderate
acne vulgaris previously treated for 3 months by a monotherapy of this substance and to
assess the effect of Skinoren® 15% gel, compared to Differin® 0. 1% gel on the efficacy and
safety during a 9-month long-term treatment period.
Azelaic Acid Iontophoresis Versus Topical Azelaic Acid Cream in the Treatment of Melasma [Recruiting]
The purpose of this prospective, randomized, controlled, single-blinded investigation is to
study the efficacy, tolerability and safety of azelaic acid iontophoresis (AAI) versus
topical treatment with azelaic acid cream in female patients with melasma.
Safety and Efficacy of Azelaic Acid Foam, 15% in Papulopustular Rosacea [Recruiting]
The purpose of this study is to assess the safety and efficacy of Azelaic Acid Foam, 15%
topically applied twice daily for 12 weeks in subjects with papulopustular rosacea compared
to its vehicle.
Azelaic Acid Versus Hydroquinone in Melasma [Recruiting]
Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea [Recruiting]
The purpose of this study is to compare the efficacy and assess the safety of CD07805/47 gel
0. 5% applied topically once daily versus azelaic acid gel 15% applied topically twice daily
in subjects with moderate to severe facial erythema of rosacea.
PATIENT REVIEWS / RATINGS / COMMENTS
Based on a total of 2 ratings/reviews, Azelex has an overall score of 5.50. The effectiveness score is 5 and the side effect score is 5. The scores are on ten point scale: 10 - best, 1 - worst.
Azelex review by 62 year old female patient
|Overall rating:|| || |
|Effectiveness:|| || Considerably Effective|
|Side effects:|| || Moderate Side Effects|
|Condition / reason:|| || acne|
|Dosage & duration:|| || twice daily application to skin (dosage frequency: twice daily) for the period of 2 years|
|Other conditions:|| || HTN|
|Other drugs taken:|| || Hydrochlorothiazide|
|Benefits:|| || Significant reduction in acne lesions. The size, frequency and severity of the lesions was reduced in the first week of use.|
|Side effects:|| || Drying, flaking, peeling of the skin where the cream was applied. These side effects were reduced by using the product only at night time.|
|Comments:|| || I noticed reduction in frequency and severity of acne lesions during the first week of use. Application was done on clean dry skin and a non-oily moisturizer was applied after the product had absorbed. Sunscreen was applied for daytime use.|
Azelex review by 44 year old female patient
|Overall rating:|| || |
|Effectiveness:|| || Ineffective|
|Side effects:|| || Severe Side Effects|
|Condition / reason:|| || Acne|
|Dosage & duration:|| || 20% Cream (dosage frequency: once daily) for the period of 2 weeks|
|Other conditions:|| || hyperpigmentation|
|Other drugs taken:|| || Synthroid and Cytomel|
|Benefits:|| || I was not able to use the cream long enough because of the side effects.|
|Side effects:|| || The cream itched and burned severely to the point of being nearly intolerable for the first week. The burning subsided in the second week, but not to the point of being usable on a daily basis.|
|Comments:|| || Application of cream nightly 15 minutes after washing. Product information advised waiting, but it still burned and itched when applying it after waiting. it had no real visible effect during the time I used it. I gave it a 2 instead of 1 because I felt a very subjective glimmer of potential improvement at the end of the period, but not enough to overcome the pain.|