Media Articles Related to Azelex (Azelaic Acid Topical)
Spironolactone: The 'Other' Hormonal Acne Therapy
Source: MedPageToday.com - medical news plus CME for physicians [2015.08.28]
(MedPage Today) -- Expert: drug is effective and its safety issues can be managed
Acne Pictures Slideshow: Quick Cover-ups, Do's and Don'ts
Source: MedicineNet Acne Specialty [2015.08.14]
Title: Acne Pictures Slideshow: Quick Cover-ups, Do's and Don'ts
Created: 8/1/2012 12:00:00 AM
Last Editorial Review: 8/14/2015 12:00:00 AM
Experimental Treatment Uses Nitric Oxide for Acne
Source: MedicineNet Acne Specialty [2015.08.03]
Title: Experimental Treatment Uses Nitric Oxide for Acne
Category: Health News
Created: 7/31/2015 12:00:00 AM
Last Editorial Review: 8/3/2015 12:00:00 AM
Could a Vitamin Play a Role in Acne Outbreaks?
Source: MedicineNet Acne Specialty [2015.06.25]
Title: Could a Vitamin Play a Role in Acne Outbreaks?
Category: Health News
Created: 6/24/2015 12:00:00 AM
Last Editorial Review: 6/25/2015 12:00:00 AM
Acne patients: 'substantial proportion' fail to collect prescribed treatment
Source: Compliance News From Medical News Today [2015.03.22]
Dermatologist-prescribed treatments are being left on pharmacy shelves by up to a quarter of people with acne, according to a new study.
Published Studies Related to Azelex (Azelaic Acid Topical)
Combination of azelaic acid 5% and clindamycin 2% for the treatment of acne
vulgaris... CONCLUSION: The profound reduction in lesion count and ASI by
Efficacy of 15% azelaic acid in psoriasis vulgaris: a randomized, controlled clinical trial. [2010.08]
BACKGROUND: Psoriasis is a common disorder affecting 1-3 percent of the general global population...
Efficacy of topical azelaic acid (AzA) gel 15% plus oral doxycycline 40 mg versus metronidazole gel 1% plus oral doxycycline 40 mg in mild-to-moderate papulopustular rosacea. [2010.06]
Rosacea is a leading reason why people seek the care of a dermatologist, accounting for nearly 7 million office visits annually. Pharmacologic treatments include both topical and oral medications, which are increasingly being used in combination, especially at the outset of therapy... These findings warrant further investigation in a sufficiently powered study.
Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. [2010.05]
INTRODUCTION: Acne vulgaris is a common problem, particularly among adolescents, which is usually resistant to monotherapy. We evaluated the efficacy and safety of a combination of azelaic acid (AA) 5% and erythromycin 2% gel (AzE) compared with AA 20% or erythromycin 2% gels in facial acne vulgaris... CONCLUSIONS: The combination of AA 5% and erythromycin 2% produced more potent therapeutic effects in comparison with erythromycin 2% or AA 20% alone, and with fewer side effects.
A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy. [2009.07]
This two-phase, multicenter study was undertaken to examine the safety and efficacy of combination therapy with oral doxycycline and topical azelaic acid (AzA) 15% gel in moderate-to-severe papulopustular rosacea and to determine the effect of subsequent maintenance monotherapy with AzA 15% gel alone...
Clinical Trials Related to Azelex (Azelaic Acid Topical)
Study for Long-term Treatment of Acne Vulgaris With Skinoren Versus Differin [Completed]
The purpose of this study is to assess the effect of Skinoren« 15% gel compared to no
therapy on the maintenance of clinical therapy success in subjects with mild to moderate
acne vulgaris previously treated for 3 months by a monotherapy of this substance and to
assess the effect of Skinoren« 15% gel, compared to Differin« 0. 1% gel on the efficacy and
safety during a 9-month long-term treatment period.
Azelaic Acid Versus Hydroquinone in Melasma [Recruiting]
Safety and Pharmacokinetics of Azelaic Acid Foam, 15% in Papulopustular Rosacea [Completed]
Finacea 15% and Brimonidine 0.33% Gel in the Treatment of Rosacea - A Pilot Study [Active, not recruiting]
The pilot study will investigate whether combination treatment of Finacea 15% Gel and
Brimonidine 0. 33% Gel could be more effective than Brimonidine 0. 33% Gel monotherapy in
treating both the papules/pustules and erythema associated with rosacea.
Azelaic Acid Iontophoresis Versus Topical Azelaic Acid Cream in the Treatment of Melasma [Recruiting]
The purpose of this prospective, randomized, controlled, single-blinded investigation is to
study the efficacy, tolerability and safety of azelaic acid iontophoresis (AAI) versus
topical treatment with azelaic acid cream in female patients with melasma.
PATIENT REVIEWS / RATINGS / COMMENTS
Based on a total of 2 ratings/reviews, Azelex has an overall score of 5.50. The effectiveness score is 5 and the side effect score is 5. The scores are on ten point scale: 10 - best, 1 - worst.
Azelex review by 62 year old female patient
|Overall rating:|| || |
|Effectiveness:|| || Considerably Effective|
|Side effects:|| || Moderate Side Effects|
|Condition / reason:|| || acne|
|Dosage & duration:|| || twice daily application to skin (dosage frequency: twice daily) for the period of 2 years|
|Other conditions:|| || HTN|
|Other drugs taken:|| || Hydrochlorothiazide|
|Benefits:|| || Significant reduction in acne lesions. The size, frequency and severity of the lesions was reduced in the first week of use.|
|Side effects:|| || Drying, flaking, peeling of the skin where the cream was applied. These side effects were reduced by using the product only at night time.|
|Comments:|| || I noticed reduction in frequency and severity of acne lesions during the first week of use. Application was done on clean dry skin and a non-oily moisturizer was applied after the product had absorbed. Sunscreen was applied for daytime use.|
Azelex review by 44 year old female patient
|Overall rating:|| || |
|Effectiveness:|| || Ineffective|
|Side effects:|| || Severe Side Effects|
|Condition / reason:|| || Acne|
|Dosage & duration:|| || 20% Cream (dosage frequency: once daily) for the period of 2 weeks|
|Other conditions:|| || hyperpigmentation|
|Other drugs taken:|| || Synthroid and Cytomel|
|Benefits:|| || I was not able to use the cream long enough because of the side effects.|
|Side effects:|| || The cream itched and burned severely to the point of being nearly intolerable for the first week. The burning subsided in the second week, but not to the point of being usable on a daily basis.|
|Comments:|| || Application of cream nightly 15 minutes after washing. Product information advised waiting, but it still burned and itched when applying it after waiting. it had no real visible effect during the time I used it. I gave it a 2 instead of 1 because I felt a very subjective glimmer of potential improvement at the end of the period, but not enough to overcome the pain.|