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Azactam (Aztreonam) - Published Studies

 
 



Azactam Related Published Studies

Well-designed clinical trials related to Azactam (Aztreonam)

Aztreonam for inhalation solution (AZLI) in patients with cystic fibrosis, mild lung impairment, and P. aeruginosa. [2011.07]

Efficacy and safety of tigecycline monotherapy compared with vancomycin-aztreonam in the treatment of complicated skin and skin structure infections in patients from India and Taiwan. [2011.04]

Efficacy and safety of tigecycline monotherapy compared with vancomycin-aztreonam in the treatment of complicated skin and skin structure infections in patients from India and Taiwan. [2011]

An 18-month study of the safety and efficacy of repeated courses of inhaled aztreonam lysine in cystic fibrosis. [2010.11]

Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection. [2010]

Lack of pharmacokinetic drug interactions following concomitant administration of telavancin with aztreonam or piperacillin/tazobactam in healthy participants. [2009.07]

Efficacy and safety of inhaled aztreonam lysine for airway pseudomonas in cystic fibrosis. [2009.05]

Piperacillin/tazobactam plus ceftazidime versus sulbactam/ampicillin plus aztreonam as empirical therapy for fever in severely neutropenic pediatric patients. [2009.04]

Inhaled aztreonam lysine for chronic airway Pseudomonas aeruginosa in cystic fibrosis. [2008.11.01]

Cefepime vs. Ampicillin/Sulbactam and Aztreonam as antibiotic prophylaxis in neurosurgical patients with external ventricular drain: result of a prospective randomized controlled clinical trial. [2006.06]

Safety and efficacy of tigecycline in treatment of skin and skin structure infections: results of a double-blind phase 3 comparison study with vancomycin-aztreonam. [2005.11]

Efficacy and safety of tigecycline monotherapy compared with vancomycin plus aztreonam in patients with complicated skin and skin structure infections: Results from a phase 3, randomized, double-blind trial. [2005.09]

Cefepime versus ticarcillin and clavulanate potassium and aztreonam for febrile neutropenia therapy in high-dose chemotherapy patients. [2003.06]

Ceftazidime versus aztreonam in the treatment of pseudomonal chronic suppurative otitis media in children. [2000]

A pharmacokinetic evaluation of concomitant administration of linezolid and aztreonam. [1999.12]

Pharmacoeconomics of aztreonam-clindamycin versus gentamicin-clindamycin in the treatment of penetrating abdominal injury. [1996.09]

Pharmacokinetics of aztreonam and imipenem in critically ill patients with pneumonia. [1996.09]

A comparison of aztreonam plus vancomycin and imipenem plus vancomycin as initial therapy for febrile neutropenic cancer patients. [1996.04.01]

Comparison of the efficacy, safety and cost of cefixime, ceftriaxone and aztreonam in the treatment of multidrug-resistant Salmonella typhi septicemia in children. [1995.07]

Clindamycin plus amikacin versus clindamycin plus aztreonam in established intraabdominal infections. [1994.07]

Randomized comparison of aztreonam and chloramphenicol in treatment of typhoid fever. [1994.03]

Superiority of aztreonam/clindamycin compared with gentamicin/clindamycin in patients with penetrating abdominal trauma. [1994.03]

Comparison of imipenem versus cefuroxime plus tobramycin as empirical therapy for febrile granulocytopenic patients and efficacy of vancomycin and aztreonam in case of failure. [1994]

Comparison of imipenem/cilastatin with the combination of aztreonam and clindamycin in the treatment of intra-abdominal infections. [1993.09]

Comparison of empiric aztreonam and aminoglycoside regimens in the treatment of serious gram-negative lower respiratory infections. [1993.01]

[A randomized controlled study on imipenem/cilastatin sodium in comparison to aztreonam + lincomycin in treating severe infections in patients with malignant tumors or hematological diseases] [1992.08]

Oral aztreonam, a poorly absorbed yet effective therapy for bacterial diarrhea in US travelers to Mexico. [1992.04.08]

Aztreonam plus vancomycin versus gentamicin plus piperacillin as empirical therapy for the treatment of fever in neutropenic patients: a randomised controlled study. [1992.04]

Nephrotoxicity and ototoxicity of aztreonam versus aminoglycoside therapy in seriously ill nonneutropenic patients. [1992.04]

Aztreonam versus colistin-neomycin for selective decontamination of the digestive tract in patients undergoing bone marrow transplantation: a randomized study. [1992.02]

[Aztreonam or gentamicin combined with piperacillin as empiric antibiotic therapy during neutropenia of patients with hematologic diseases] [1992.02]

A comparison of aztreonam and ceftazidime in the treatment of respiratory infections in adults with cystic fibrosis. [1992]

Aztreonam compared to chloramphenicol in the treatment of enteric fevers. [1992]

A comparative trial of aztreonam versus gentamicin in the treatment of urinary tract infections. [1992]

A comparative study on aztreonam, ceftazidime and amikacin in the treatment of complicated urinary tract infections. [1991.12]

Aztreonam vs. cefotaxime in the treatment of gram-negative spontaneous peritonitis in cirrhotic patients. [1991.07]

Comparison of two schedules of cefoperazone plus aztreonam in the treatment of neutropenic patients with fever. [1991.07]

Aztreonam therapy in children with febrile neutropenia: a randomized trial of aztreonam plus flucloxacillin versus piperacillin plus gentamicin. [1991.07]

Metabolic tolerance to arginine: implications for the safe use of arginine salt-aztreonam combination in the neonatal period. [1991.06]

Aztreonam plus clindamycin versus tobramycin plus clindamycin in the treatment of intraabdominal infections. [1991.05]

Multicenter trial of prophylaxis with clindamycin plus aztreonam or cefotaxime in gynecologic surgery. [1991.05]

Aztreonam versus gentamicin for short-term prophylaxis in biliary and gastric surgery. [1991.05]

Sensitization to aztreonam and cross-reactivity with other beta-lactam antibiotics in high-risk patients with cystic fibrosis. [1991.01]

A randomised prospective comparison of oral ofloxacin and intraperitoneal vancomycin plus aztreonam in the treatment of bacterial peritonitis complicating continuous ambulatory peritoneal dialysis (CAPD). [1991]

A comparative efficacy and safety study of teicoplanin plus aztreonam versus gentamicin plus piperacillin in haematology oncology patients with clinically diagnosed septicaemia. [1990.12]

A single dose of aztreonam in the prevention of urinary tract infections in elderly catheterized patients. [1990.06]

Ceftriaxone versus aztreonam plus cefazolin for infections in cancer patients with adequate neutrophil counts. [1990.05]

A comparison of aztreonam/metronidazole and cefotaxime/metronidazole in elective colorectal surgery: antimicrobial prophylaxis must include gram-positive cover. [1990.04]

Evaluation of aztreonam and ampicillin vs. amikacin and ampicillin for treatment of neonatal bacterial infections. [1990.03]

Comparative efficacies of aztreonam and chloramphenicol in children with typhoid fever. [1990.01]

Antipseudomonal therapy in cystic fibrosis: aztreonam and amikacin versus ceftazidime and amikacin administered intravenously followed by oral ciprofloxacin. [1989.10]

Randomized comparison of aztreonam and cefuroxime in gram-negative upper urinary tract infections. [1989.09]

Randomized clinical trial of aztreonam and aminoglycoside antibiotics in the treatment of serious infections caused by gram-negative bacilli. [1989.08]

A comparative analysis of aztreonam + clindamycin versus tobramycin + clindamycin or amikacin + mezlocillin in the treatment of gram-negative lower respiratory tract infections. [1989]

Multicenter comparative study of aztreonam and gentamicin in the treatment of renal and urinary tract infections. [1989]

Multicenter study of aztreonam in the prophylaxis of colorectal, gynecologic and urologic surgery. [1989]

Comparison of aztreonam plus clindamycin with tobramycin plus clindamycin in the treatment of intra-abdominal infections. [1989]

Therapeutic efficacy of the combination of aztreonam with cefotaxime in the treatment of severe nosocomial pneumonia. Comparative study against amikacin combined with cefotaxime. [1989]

Controlled trial of aztreonam vs. tobramycin and azlocillin for acute pulmonary exacerbations of cystic fibrosis. [1988.03]

A comparative study of aztreonam and procaine penicillin/probenecid in the treatment of uncomplicated gonorrhoea. [1988]

Systemic perioperative prophylaxis in elective oncological colorectal surgery: cefotetan versus clindamicin plus aztreonam. [1988]

A comparative study of cefoxitin, cefotaxime, moxalactam and aztreonam kinetics in saliva. [1987.10]

Double-blind study comparing aztreonam with placebo for prophylaxis of infection following prostatic surgery. [1987.10]

Single intramuscular injection of aztreonam in the treatment of uncomplicated gonorrhoea in women. [1987]

Well-designed clinical trials possibly related to Azactam (Aztreonam)

New insights into meticillin-resistant Staphylococcus aureus (MRSA) pathogenesis, treatment and resistance. [2012]

Integrated safety summary of CANVAS 1 and 2 trials: Phase III, randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. [2010.11]

CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. [2010.11]

CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. [2010.11]

Safety and efficacy of intravenous tigecycline in subjects with secondary bacteremia: pooled results from 8 phase III clinical trials. [2010.01.15]

Safety and efficacy of intravenous tigecycline in subjects with secondary bacteremia: pooled results from 8 phase III clinical trials. [2010]

Overview of tigecycline efficacy and safety in the treatment of complicated skin and skin structure infections - a European perspective. [2008.10]

Impact of linezolid on economic outcomes and determinants of cost in a clinical trial evaluating patients with MRSA complicated skin and soft-tissue infections. [2006.06]

Continuation of a randomized, double-blind, multicenter study of linezolid versus vancomycin in the treatment of patients with nosocomial pneumonia. [2003.03]

Treatment of nosocomial postoperative pneumonia in cancer patients: a prospective randomized study. [2001.03]

Linezolid (PNU-100766) versus vancomycin in the treatment of hospitalized patients with nosocomial pneumonia: a randomized, double-blind, multicenter study. [2001.02.01]

The effect of acetazolamide on the kinetics of four newer beta-lactams in the aqueous humor. [2001.02]

Treatment of pneumonia in mechanically ventilated trauma patients. Results of a prospective trial. [1997.10]

Outpatient treatment of febrile episodes in low-risk neutropenic patients with cancer. [1993.06.01]

Enterobacteriaceae and neonatal necrotising enterocolitis. [1992.01]

Infections in patients in intensive care units: can the combination of a monobactam and a penicillin replace the classic combination of a beta-lactam agent and an aminoglycoside? [1991.05]

To assess the efficacy of prophylaxis in digestive tract surgery using a predictive model of complication risk. [1990.12]

Randomized trial of combination antibiotic therapy in patients with hematological disorders. Hanshin Study Group of Hematopoietic Disorders and Infection. [1990.01]

Preoperative therapeutic considerations in chronic suppurative otitis media. [1989.06]

Carumonam versus ceftazidime for urinary tract infections. [1988.07]

Carumonam (Ro 17-2301; AMA-1080) compared with gentamicin for treatment of complicated urinary tract infections. [1988.04]

Other research related to Azactam (Aztreonam)

Inhaled aztreonam for chronic Burkholderia infection in cystic fibrosis: a placebo-controlled trial. [2014]

Aztreonam inhalation solution for suppressive treatment of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis. [2011.11]

Tolerability of aztreonam in patients with cell-mediated allergy to beta-lactams. [2011]

Aztreonam inhalation solution for suppressive treatment of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis. [2011]

Aztreonam lysine for inhalation solution: in cystic fibrosis. [2010.10.01]

Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection. [2010.09.15]

Aztreonam lysine: a novel inhalational antibiotic for cystic fibrosis. [2010.08]

An 18-month study of the safety and efficacy of repeated courses of inhaled aztreonam lysine in cystic fibrosis. [2010.07.29]

Optimal airway antimicrobial therapy for cystic fibrosis: the role of inhaled aztreonam lysine. [2010.06]

Inhaled aztreonam. [2010.05]

[Tolerance and efficacy of ceftazidime in combination with aztreonam for exacerbations of cystic fibrosis]. [2010.05]

Inhaled Aztreonam Lysine for Chronic Airway Pseudomonas aeruginosa in Cystic Fibrosis. [2008.07.24]

Tolerability of aztreonam in patients with IgE-mediated hypersensitivity to beta-lactams. [2008.04]

A phase 2 study of aztreonam lysine for inhalation to treat patients with cystic fibrosis and Pseudomonas aeruginosa infection. [2008.01]

[Is aztreonam could become "a challenger" for treatment of Gram negative infections? May be an answer from microbiological data: in vitro study including 36,485 strains of enterobacteria and Pseudomonas] [2007.12]

Risk factors for and impact of infection or colonization with aztreonam-resistant Pseudomonas aeruginosa. [2007.10]

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