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Axsain (Capsaicin / Lidocaine Hydrochloride) - Published Studies

 
 



Axsain Related Published Studies

Well-designed clinical trials related to Axsain (Capsaicin / Lidocaine)

Topical capsaicin (low concentration) for chronic neuropathic pain in adults. [2012]

Capsaicin instillation for postoperative pain following total knee arthroplasty: a preliminary report of a randomized, double-blind, parallel-group, placebo-controlled, multicentre trial. [2011.12.01]

A randomized, double-blind, parallel trial comparing capsaicin nasal spray with placebo in subjects with a significant component of nonallergic rhinitis. [2011.08]

Self-reported sleep duration associated with distraction analgesia, hyperemia, and secondary hyperalgesia in the heat-capsaicin nociceptive model. [2011.07]

Effects of lidocaine patch on intradermal capsaicin-induced pain: a double-blind, controlled trial. [2011.03]

A multicenter, randomized, double-blind, controlled study of NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia. [2011.01]

Effects of lidocaine patch on intradermal capsaicin-induced pain: a double-blind, controlled trial. [2011]

Effectiveness and safety of topical capsaicin cream in the treatment of chronic soft tissue pain. [2010.12]

Effect of duration of postherpetic neuralgia on efficacy analyses in a multicenter, randomized, controlled study of NGX-4010, an 8% capsaicin patch evaluated for the treatment of postherpetic neuralgia. [2010.10.11]

Efficacy of symptomatic control of knee osteoarthritis with 0.0125% of capsaicin versus placebo. [2010.10]

A multicenter, randomized, double-blind, controlled dose finding study of NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia. [2010.10]

Effect of oral intake of capsaicinoid beadlets on catecholamine secretion and blood markers of lipolysis in healthy adults: a randomized, placebo controlled, double-blind, cross-over study. [2010.07.15]

Capsaicin-induced central sensitization evokes segmental increases in trigger point sensitivity in humans. [2010.07]

A randomized, controlled, open-label study of the long-term effects of NGX-4010, a high-concentration capsaicin patch, on epidermal nerve fiber density and sensory function in healthy volunteers. [2010.06]

NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomized, double-blind, controlled study with an open-label extension. [2010.04]

Topical capsaicin therapy for uremic pruritus in patients on hemodialysis. [2010.04]

Capsaicin jelly against migraine pain. [2010.03]

Late sensory function after intraoperative capsaicin wound instillation. [2010.02]

Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974). [2010.01]

Efficacy of symptomatic control of knee osteoarthritis with 0.0125% of capsaicin versus placebo. [2010]

Effect of duration of postherpetic neuralgia on efficacy analyses in a multicenter, randomized, controlled study of NGX-4010, an 8% capsaicin patch evaluated for the treatment of postherpetic neuralgia. [2010]

A multicenter, randomized, double-blind, controlled dose finding study of NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia. [2010]

Effect of oral intake of capsaicinoid beadlets on catecholamine secretion and blood markers of lipolysis in healthy adults: a randomized, placebo controlled, double-blind, cross-over study. [2010]

Topical capsaicin therapy for uremic pruritus in patients on hemodialysis. [2010]

Late sensory function after intraoperative capsaicin wound instillation. [2010]

A comparison of two formulations of intradermal capsaicin as models of neuropathic pain in healthy volunteers. [2009.10]

Pharmacokinetic analysis of capsaicin after topical administration of a high-concentration capsaicin patch to patients with peripheral neuropathic pain. [2009.08]

The effect of local anaesthetic on age-related capsaicin-induced mechanical hyperalgesia--a randomised, controlled study. [2009.07]

Effects of capsaicin, green tea and CH-19 sweet pepper on appetite and energy intake in humans in negative and positive energy balance. [2009.06]

The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety. [2009.06]

Vascular and psychophysical effects of topical capsaicin application to orofacial tissues. [2009.06]

Pharmacokinetic and the effect of capsaicin in Capsicum frutescens on decreasing plasma glucose level. [2009.01]

Subcutaneous Botulinum toxin type A reduces capsaicin-induced trigeminal pain and vasomotor reactions in human skin. [2009.01]

Effects of chili on postprandial gastrointestinal symptoms in diarrhoea predominant irritable bowel syndrome: evidence for capsaicin-sensitive visceral nociception hypersensitivity. [2009.01]

COX-2 inhibition attenuates cough reflex sensitivity to inhaled capsaicin in patients with asthma. [2009]

Effect of morphine and pregabalin compared with diphenhydramine hydrochloride and placebo on hyperalgesia and allodynia induced by intradermal capsaicin in healthy male subjects. [2008.12]

NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study. [2008.12]

Capsaicin provocation using two different inhalation devices. [2008.12]

A randomized controlled trial comparing treatment regimens for acute pain for topical oleoresin capsaicin (pepper spray) exposure in adult volunteers. [2008.10]

Interactions between glutamate and capsaicin in inducing muscle pain and sensitization in humans. [2008.07]

Controlled trial of high-concentration capsaicin patch for treatment of painful HIV neuropathy. [2008.06.10]

Calcitonin gene-related peptide8-37 antagonizes capsaicin-induced vasodilation in the skin: evaluation of a human in vivo pharmacodynamic model. [2008.04]

Hypersensitivity for capsaicin in patients with functional dyspepsia. [2008.02]

Comparison of topical capsaicin and betamethasone in the treatment of chronic skin lesions due to sulfur mustard exposure. [2008]

Dose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteers. [2007.11]

Mechanisms of adrenosensitivity in capsaicin induced hyperalgesia. [2007.10]

Botulinum toxin A does not alter capsaicin-induced pain perception in human skin. [2007.09.15]

Botulinum toxin type A reduces capsaicin-evoked pain and neurogenic vasodilatation in human skin. [2007.07]

Reaction to topical capsaicin in spinal cord injury patients with and without central pain. [2007.05]

Influence of topical capsaicin on facial sensitivity in response to experimental pain. [2007.01]

The effect of codeine on the Urge-to-Cough response to inhaled capsaicin. [2007]

Intravesical glucidic capsaicin versus glucidic solvent in neurogenic detrusor overactivity: A double blind controlled randomized study. [2006]

Inhalation method determines outcome of capsaicin inhalation in patients with chronic cough due to sensory hyperreactivity. [2006]

Evaluation of capsaicin ointment at the Korean hand acupressure point K-D2 for prevention of postoperative nausea and vomiting. [2005.12]

Gastroprotection induced by capsaicin in healthy human subjects. [2005.09.07]

Effects of intradermal foot and forearm capsaicin injections in normal and vulvodynia-afflicted women. [2005.09]

Sensory and gastrointestinal satiety effects of capsaicin on food intake. [2005.06]

Capsaicin troche for swallowing dysfunction in older people. [2005.05]

Comparison of the analgesic effects of a fixed-dose combination of orphenadrine and diclofenac (Neodolpasse) with its single active ingredients diclofenac and orphenadrine: a placebo-controlled study using laser-induced somatosensory-evoked potentials from capsaicin-induced hyperalgesic human skin. [2005]

Nitric-oxide mediated effects of transdermal capsaicin patches on the ischemic threshold in patients with stable coronary disease. [2004.09]

Areas of capsaicin-induced secondary hyperalgesia and allodynia are reduced by a single chiropractic adjustment: a preliminary study. [2004.07]

Lack of effect of two oral sodium channel antagonists, lamotrigine and 4030W92, on intradermal capsaicin-induced hyperalgesia model. [2004.06]

Differential effects of peripheral ketamine and lidocaine on skin flux and hyperalgesia induced by intradermal capsaicin in humans. [2004.03]

Systemic capsaicin for burning mouth syndrome: short-term results of a pilot study. [2004.02]

Intravesical capsaicin versus resiniferatoxin for the treatment of detrusor hyperreflexia in spinal cord injured patients: a double-blind, randomized, controlled study. [2004.01]

Analgesic effects of low-dose intravenous orphenadrine in the state of capsaicin hyperalgesia. A randomised, placebo-controlled, double-blind cross-over study using laser somatosensory evoked potentials obtained from capsaicin-irritated skin in healthy volunteers. [2004]

A randomized study of the effect of oral lamotrigine and hydromorphone on pain and hyperalgesia following heat/capsaicin sensitization. [2003.09]

Effect of capsaicin on substrate oxidation and weight maintenance after modest body-weight loss in human subjects. [2003.09]

Topical capsaicin--a novel and effective treatment for idiopathic intractable pruritus ani: a randomised, placebo controlled, crossover study. [2003.09]

Intranasal capsaicin reduces nasal hyperreactivity in idiopathic rhinitis: a double-blind randomized application regimen study. [2003.08]

Gut pain and hyperalgesia induced by capsaicin: a human experimental model. [2003.07]

Magnesium-aluminum hydroxide suspension for the treatment of dermal capsaicin exposures. [2003.06]

The heat/capsaicin sensitization model: a methodologic study. [2003.04]

Cough receptor sensitivity to capsaicin does not change after allergen bronchoprovocation in allergic asthma. [2003.01]

Increased capsaicin cough sensitivity in patients with multiple chemical sensitivity. [2002.11]

Postdelivery of alfentanil and ketamine has no effect on intradermal capsaicin-induced pain and hyperalgesia. [2002.11]

The effect of chronic oral desipramine on capsaicin-induced allodynia and hyperalgesia: a double-blinded, placebo-controlled, crossover study. [2002.10]

Naloxone increases pain induced by topical capsaicin in healthy human volunteers. [2002.09]

The effects of capsaicin topical therapy in dogs with atopic dermatitis: a randomized, double-blinded, placebo-controlled, cross-over clinical trial. [2002.06]

Intravesical capsaicin versus resiniferatoxin in patients with detrusor hyperreflexia: a prospective randomized study. [2002.04]

Concentration-effect relationships for intravenous alfentanil and ketamine infusions in human volunteers: effects on acute thresholds and capsaicin-evoked hyperpathia. [2002.01]

Effect of systemic adenosine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers. [2001.09]

Effect of intravenous magnesium on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers. [2001.06]

Effects of stress and relaxation on capsaicin-induced pain. [2001.06]

The ACE gene polymorphism and cough threshold for capsaicin after cilazapril usage. [2001.02]

Intranasal capsaicin is lacking therapeutic effect in perennial allergic rhinitis to house dust mite. A placebo-controlled study. [2000.12]

Peripheral lidocaine but not ketamine inhibits capsaicin-induced hyperalgesia in humans. [2000.10]

The effect of systemic lidocaine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers. [2000.10]

Effect of oral mexiletine on capsaicin-induced allodynia and hyperalgesia: a double-blind, placebo-controlled, crossover study. [2000.09]

[Effect of intranasal treatment with capsaicin on polyp recurrence after polypectomy and ethmoidectomy] [2000.08]

Effects of relaxation and stress on the capsaicin-induced local inflammatory response. [2000.07]

Capsaicin-induced muscle hyperalgesia in the exercised and non-exercised human masseter muscle. [2000.06]

Cough provocation with capsaicin is an objective way to test sensory hyperreactivity in patients with asthma-like symptoms. [2000.06]

Topical application of doxepin hydrochloride, capsaicin and a combination of both produces analgesia in chronic human neuropathic pain: a randomized, double-blind, placebo-controlled study. [2000.06]

Differential effects of systemically administered ketamine and lidocaine on dynamic and static hyperalgesia induced by intradermal capsaicin in humans. [2000.02]

Effect of oral mexiletine on the cough response to capsaicin and tartaric acid. [2000.02]

Topical application of capsaicin for the treatment of localized pain in the temporomandibular joint area. [2000.01]

Effect of intranasal treatment with capsaicin on the recurrence of polyps after polypectomy and ethmoidectomy. [2000.01]

Topical capsaicin in the management of HIV-associated peripheral neuropathy. [2000.01]

Relative potency of epidural to intrathecal clonidine differs between acute thermal pain and capsaicin-induced allodynia. [2000.01]

The analgesic efficacy of topical capsaicin is enhanced by glyceryl trinitrate in painful osteoarthritis: a randomized, double blind, placebo controlled study. [2000]

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