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Avalide (Irbesartan / Hydrochlorothiazide) - Summary

 

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USE IN PREGNANCY

When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. When pregnancy is detected, AVALIDE should be discontinued as soon as possible. (See WARNINGS: Fetal/Neonatal Morbidity and Mortality.)

 

AVALIDE SUMMARY

AVALIDE®
(irbesartan-hydrochlorothiazide)
Tablets

AVALIDE® (irbesartan-hydrochlorothiazide) Tablets is a combination of an angiotensin II receptor antagonist (AT1 subtype), irbesartan, and a thiazide diuretic, hydrochlorothiazide (HCTZ).

AVALIDE (irbesartan-hydrochlorothiazide) Tablets is indicated for the treatment of hypertension. This fixed dose combination is not indicated for initial therapy (see DOSAGE AND ADMINISTRATION).

AVALIDE NEWS HIGHLIGHTS

Media Articles Related to Avalide (Irbesartan / Hydrochlorothiazide)

GP-Led Hypertension Health Promotion Campaign Delivers Response Rates Of 76%
Source: Hypertension News From Medical News Today [2008.08.21]

Hypertension May Result From Poor Teen Sleep Habits, Lead To CVD
Source: Cardiovascular / Cardiology News From Medical News Today [2008.08.20]

Poor Sleep May Lead to Hypertension in Teens
Source: MedPage Today Cardiovascular [2008.08.18]

Better Hypertension Treatment By Determining How The Body Regulates Blood Pressure In Response To Daily Stress
Source: Hypertension News From Medical News Today [2008.08.16]

Tracleer(R) (bosentan) Receives EU Approval For Treatment Of Patients With Mildly Symptomatic Pulmonary Arterial Hypertension
Source: Hypertension News From Medical News Today [2008.08.04]

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Published Studies Related to Avalide (Irbesartan / Hydrochlorothiazide)

Efficacy and safety of irbesartan/HCTZ combination therapy as initial treatment for rapid control of severe hypertension. [2006.12]

Irbesartan/HCTZ fixed combinations in patients of different racial/ethnic groups with uncontrolled systolic blood pressure on monotherapy. [2006.04]

Ambulatory blood pressure comparison of the anti-hypertensive efficacy of fixed combinations of irbesartan/hydrochlorothiazide and losartan/hydrochlorothiazide in patients with mild-to-moderate hypertension. [2005.11]

Effect of delapril-manidipine combination vs irbesartan-hydrochlorothiazide combination on fibrinolytic function in hypertensive patients with type II diabetes mellitus. [2004.10]

[Comparison of the antihypertensive activity of fosinopril and irbesartan] [2002.11]

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Clinical Trials Related to Avalide (Irbesartan / Hydrochlorothiazide)

Adalat ® XL® vs Diltiazem on Proteinuria and Blood Pressure in Hypertensive Diabetic Patients [Not yet recruiting]

AMISH : Aprovel for Management of Isolated Systolic Hypertension [Completed]

Irbesartan/Hydrochlorothiazide to Control Elevated Blood Pressure to Target in Moderate- to Severe Hypertensive Patients [Recruiting]

I SAVE - Irbesartan in Mild to Moderate Hypertensive Patients [Completed]

I SELECT - Irbesartan In Hypertensive Patients With Left Ventricular Hypertrophy [Recruiting]

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Page last updated: 2008-08-21

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