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Atropine (Atropine Sulfate) - Warnings and Precautions



This drug is effective in very low dosage and overdose may cause permanent damage or death, especially in children.


Doses of 0.5 to 1 mg of atropine are mildly stimulating to the central nervous system. Larger doses may produce mental disturbances; still larger doses are depressing. Death from atropine poisoning, though rare, is usually due to paralysis of the medullary centers.

Pregnancy: Teratogenic effects: Pregnancy Category B. Reproduction studies have been performed in mice in doses of 50 mg/kg of body weight and have revealed no evidence of impaired
fertility or harm to the fetus due to Atropine Sulfate. There are, however, no adequate and well controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Page last updated: 2014-07-15

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