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Artiss (Fibrinogen / Thrombin Human) - Drug Interactions, Contraindications, Overdosage, etc



No interaction studies have been performed.


To avoid the formation of excess granulation tissue and to ensure gradual absorption of the polymerized fibrin sealant, apply only a thin layer of ARTISS (see METHOD OF APPLICATION).


Intravascular Application

Do not inject ARTISS directly into blood vessels. Intravascular application of ARTISS may result in life-threatening thromboembolic events.

Aprotinin Hypersensitivity

Do not use ARTISS in individuals with a known hypersensitivity to aprotinin and/or hypersensitivity to any of the active substances or excipients (see WARNINGS/PRECAUTIONS, Hypersensitivity/Allergic/Anaphylactic Reactions and ADVERSE REACTIONS, Overall Adverse Reactions).

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