ARTISS [Fibrin Sealant], Vapor Heated, Solvent Detergent Treated, (ARTISS) is a two-component fibrin sealant made from pooled human plasma. When combined, the two components, Sealer Protein (Human) and Thrombin (Human), mimic the final stage of the blood coagulation cascade.
ARTISS is indicated to adhere autologous skin grafts to surgically prepared wound beds resulting from burns in adult and pediatric populations greater than or equal to 1 year of age.
ARTISS is not indicated for hemostasis.
Media Articles Related to Artiss (Fibrinogen / Thrombin Human)
Burns (First Aid)
Source: MedicineNet Hyperkalemia Specialty [2015.02.20]
Title: Burns (First Aid)
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 2/20/2015 12:00:00 AM
Burn Risk Seen with Topical Pain Relievers
Source: MedPage Today Product Alert [2012.09.13]
WASHINGTON -- The FDA warned Thursday of the risks of rare but serious chemical burns with certain over-the-counter topical pain relievers, including Bengay, Capzasin, Flexall, Icy Hot, and Mentholatum.
Published Studies Related to Artiss (Fibrinogen / Thrombin Human)
Randomized, controlled, phase 3 study to evaluate the safety and efficacy of
fibrin sealant VH S/D 4 s-apr (Artiss) to improve tissue adherence in subjects
undergoing rhytidectomy. 
dead space in patients undergoing rhytidectomy... CONCLUSIONS: Adjunct use of FS VH S/D 4 s-apr in rhytidectomy was proven safe in
Human fibrinogen/thrombin-coated collagen patch to control intraoperative severe pulmonary hemorrhage and air leakage after correction of a ruptured thoracic aortic aneurysm. [2011.03]
Lung erosion represents a dreadful complication in patients affected by thoracic aortic aneurysms.
Wound healing and the immune response in swine treated with a hemostatic bandage composed of salmon thrombin and fibrinogen. [2009.10]
We investigated the inflammatory response in pigs exposed to salmon fibrinogen/thrombin dressings. Animals were exposed to the material in 3 ways: (a) thrombin and fibrinogen were injected intravenously, (b) dual full-thickness skin lesions were surgically created on the dorsal aspect of the swine and treated with the fibrinogen/thrombin bandage and a commercial bandage or (c) a fibrinogen/thrombin bandage was inserted through an abdominal incision into the peritoneal cavity...
Clinical Trials Related to Artiss (Fibrinogen / Thrombin Human)
Efficacy and Safety of ARTISS for Flap Adherence in Abdominoplasty [Completed]
A Study Evaluating the Efficacy and Safety of ARTISS Human Fibrin Sealant as Used in External Rhinoplasty [Recruiting]
Rhinoplasty (nasal reconstruction i. e. "a nose job") is a surgical procedure performed on
the nose to correct a medical problem or change the appearance of the nose. During the
healing process, swelling and/or bruising is likely to occur. A drug called ARTISS Fibrin
Sealant may or may not lessen these effects. This study is looking to see the effects of
ARTISS on adhering tissue and improving wound healing in an external rhinoplasty. The
purpose of this study is to evaluate the safety and effectiveness of rhinoplasty using
ARTISS compared to rhinoplasty without using ARTISS in patients undergoing rhinoplasty
performed through an external approach.
Efficacy and Safety of Fibrin Sealant (FS) VH S/D-APR for Hemostasis and Wound Healing in Endoscopic Browlift [Recruiting]
The primary objective is to evaluate the safety and efficacy of Artiss (Fibrin Sealant) in
reducing the incidence of early postoperative bruising and swelling.
Efficacy and Safety of FS VH S/D 4 S-apr for Flap Adherence in Rhytidectomy [Completed]
The purpose of the study is to compare the safety and efficacy of FS VH S/D 4 s-apr versus
standard of care in adhering tissue and improving wound healing in subjects undergoing
Reports of Suspected Artiss (Fibrinogen / Thrombin Human) Side Effects
Drug Ineffective (26),
FAT Necrosis (20),
Postoperative Wound Infection (8),
Wound Dehiscence (8),
Bacterial Test Positive (2), more >>