ARTISS [Fibrin Sealant], Vapor Heated, Solvent Detergent Treated, (ARTISS) is a two-component fibrin sealant made from pooled human plasma. When combined, the two components, Sealer Protein (Human) and Thrombin (Human), mimic the final stage of the blood coagulation cascade.
ARTISS is indicated to adhere autologous skin grafts to surgically prepared wound beds resulting from burns in adult and pediatric populations.
ARTISS is not indicated for hemostasis.
Media Articles Related to Artiss (Fibrinogen / Thrombin Human)
Topical Products for Muscle, Joint Pain May Cause Burns: FDA
Source: MedicineNet Muscle Cramps Specialty [2012.09.14]
Title: Topical Products for Muscle, Joint Pain May Cause Burns: FDA
Category: Health News
Created: 9/14/2012 10:05:00 AM
Last Editorial Review: 9/14/2012 12:00:00 AM
Injuries from the Tough Mudder Extreme Sports Event
Source: Sports Medicine / Fitness News From Medical News Today [2013.11.19]
The Tough Mudder, an extreme sports event that bills itself as "probably the toughest event on the planet," resulted in injuries ranging from multiple electrical burns to seizure-induced Todd's paralysis.
Study provides insight into combined radiation injury from possible nuclear disaster
Source: Bio-terrorism / Terrorism News From Medical News Today [2013.10.03]
A nuclear bomb or nuclear reactor accident can produce a deadly combination of radiation exposure and injuries such as burns and trauma.Now the first study of its kind in 50 years is providing new insights into this phenomenon, called combined radiation injury (CRI).
Burn Risk Seen with Topical Pain Relievers
Source: MedPage Today Product Alert [2012.09.13]
WASHINGTON -- The FDA warned Thursday of the risks of rare but serious chemical burns with certain over-the-counter topical pain relievers, including Bengay, Capzasin, Flexall, Icy Hot, and Mentholatum.
Published Studies Related to Artiss (Fibrinogen / Thrombin Human)
Human fibrinogen/thrombin-coated collagen patch to control intraoperative severe pulmonary hemorrhage and air leakage after correction of a ruptured thoracic aortic aneurysm. [2011.03]
Lung erosion represents a dreadful complication in patients affected by thoracic aortic aneurysms.
Wound healing and the immune response in swine treated with a hemostatic bandage composed of salmon thrombin and fibrinogen. [2009.10]
We investigated the inflammatory response in pigs exposed to salmon fibrinogen/thrombin dressings. Animals were exposed to the material in 3 ways: (a) thrombin and fibrinogen were injected intravenously, (b) dual full-thickness skin lesions were surgically created on the dorsal aspect of the swine and treated with the fibrinogen/thrombin bandage and a commercial bandage or (c) a fibrinogen/thrombin bandage was inserted through an abdominal incision into the peritoneal cavity...
Clinical Trials Related to Artiss (Fibrinogen / Thrombin Human)
A Study Evaluating the Efficacy and Safety of ARTISS Human Fibrin Sealant as Used in External Rhinoplasty [Not yet recruiting]
Rhinoplasty (nasal reconstruction i. e. "a nose job") is a surgical procedure performed on
the nose to correct a medical problem or change the appearance of the nose. During the
healing process, swelling and/or bruising is likely to occur. A drug called ARTISS Fibrin
Sealant may or may not lessen these effects. This study is looking to see the effects of
ARTISS on adhering tissue and improving wound healing in an external rhinoplasty. The
purpose of this study is to evaluate the safety and effectiveness of rhinoplasty using
ARTISS compared to rhinoplasty without using ARTISS in patients undergoing rhinoplasty
performed through an external approach.
Efficacy and Safety of ARTISS for Flap Adherence in Abdominoplasty [Recruiting]
Efficacy and Safety of Fibrin Sealant (FS) VH S/D-APR for Hemostasis and Wound Healing in Endoscopic Browlift [Recruiting]
The primary objective is to evaluate the safety and efficacy of Artiss (Fibrin Sealant) in
reducing the incidence of early postoperative bruising and swelling.
Reports of Suspected Artiss (Fibrinogen / Thrombin Human) Side Effects
Drug Ineffective (26),
FAT Necrosis (20),
Postoperative Wound Infection (8),
Wound Dehiscence (8),
Bacterial Test Positive (2), more >>