Published Studies Related to Arginine Injection
Oral L-arginine supplementation in patients with mild arterial hypertension and
its effect on plasma level of asymmetric dimethylarginine, L-citruline,
L-arginine and antioxidant status. 
CONCLUSIONS: L-arginine supplementation increases plasma arginine, citrulline and
Instant dentin hypersensitivity relief of a single topical application of an
in-office desensitizing paste containing 8% arginine and calcium carbonate: A
split-mouth, randomized-controlled study. 
Abstract Objective. The aim of this study was to evaluate the clinical efficacy
of an in-office desensitizing paste containing 8% arginine and calcium carbonate
relative to calcium carbonate alone in the reduction of dentin hypersensitivity
in a randomized, double-blind, split-mouth clinical trial...
Intravenous arginine and human skin graft donor site healing: a randomized controlled trial. [2011.05]
BACKGROUND AND AIMS: Studies evaluating the effect of arginine supplementation in human wound healing are inhomogeneous with conflicting results. This study aims to clarify the role of arginine supplementation in the healing of human skin graft donor sites... CONCLUSION: Intravenous arginine supplementation does not improve angiogenesis, reepithelialization or neutrophil influx in healing of human skin graft donor sites. Copyright (c) 2010 Elsevier Ltd and ISBI. All rights reserved.
Phase II study of pegylated arginine deiminase for nonresectable and metastatic hepatocellular carcinoma. [2010.05.01]
PURPOSE: It is well known that hepatocellular carcinoma (HCC) is an arginine auxotroph due to argininosuccinate synthetase I deficiency. This study's purpose was to evaluate the effects of pegylated arginine deiminase (ADI) in terms of toxicity, tumor response, alpha-fetoprotein (AFP) levels, and serum arginine levels... CONCLUSION: Pegylated ADI is a promising drug that capitalizes on a significant enzymatic deficiency in HCC. It is safe, well tolerated, and may benefit patients with unresectable HCC.
L-arginine supplemented nondiluted blood cardioplegia: a clinical trial. [2010.04]
AIM: L-arginine was shown to improve protection of the myocardium during coronary artery bypass graft (CABG) surgery. The objective of the present study was to determine the concentration of L-arginine to obtain the most effective protection of the myocardium during CABG surgery... CONCLUSION: Nondiluted blood cardioplegic solution supplemented with 4 mmol/L of L-arginine was associated with a significant decrease of myocardial lactate release after aortic cross-clamping and reperfusion during CABG surgery.
Clinical Trials Related to Arginine Injection
Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease [Enrolling by invitation]
The purpose of this study is to determine whether giving extra arginine to patients with
sickle cell disease seeking treatment for vaso-occlusive painful events (VOE) will decrease
pain scores, decrease need for pain medications or decrease length of hospital stay or
emergency department visit.
Efficacy and Safety of L Arginine to Prevent Preeclampsia [Completed]
Randomized double-blind controled clinical trial to assess the efficacy and safety of
L-arginine to prevent preeclampsia.
applied to pregnant women with risk factors for preeclampsia. the main result was the
development of preeclampsia as well as side effects to taking l arginine besides perinatal
Characterization of the Metabolic Fate of an Oral Arginine Form [Completed]
The purpose of this study is to compare the metabolic fate of two oral forms of L-Arginine
in healthy subjects featuring metabolic syndrome related risk factors
Effects of L-arginine Supplementation in Adults With Moderate to Severe Asthma [Completed]
Nitric oxide is an important marker of airway inflammation in asthma. Nitric oxide may have
a protective role in patients with moderate to severe asthma. The investigators believe
that a natural amino acid, L-arginine, that augments nitric oxide levels can decrease asthma
exacerbations and improve the asthma care of moderate to severe asthma patients.
This study is a randomized, placebo controlled trial in which subjects will receive either 3
months of L-arginine supplementation or a placebo. The investigators will monitor subjects'
symptoms, the number of asthma exacerbations, and lung function. In addition, we will draw
blood, obtain induced sputum samples and measure exhaled breath nitric oxide levels at each
L-arginine and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis (TB) [Completed]
The purpose of this study is to determine whether adjunctive L-arginine and vitamin D can
improve response to standard short course TB therapy in people with newly diagnosed