DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Arestin (Minocycline Hydrochloride) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

The most frequently reported nondental treatment-emergent adverse events in the 3 multicenter US trials were headache, infection, flu syndrome, and pain.

Table 5: Adverse Events (AEs) Reported in ≥3% of the Combined Clinical Trial Population of 3 Multicenter US Trials by Treatment Group
SRP
Alone
N=250
SRP +
Vehicle
N=249
SRP +
ARESTIN®
N=423
Number (%) of Patients Treatment-emergent AEs 62.4% 71.9% 68.1%
Total Number of AEs 543 589 987
  Periodontitis 25.6% 28.1% 16.3%
  Tooth Disorder 12.0% 13.7% 12.3%
  Tooth Caries 9.2% 11.2% 9.9%
  Dental Pain 8.8% 8.8% 9.9%
  Gingivitis 7.2% 8.8% 9.2%
  Headache 7.2% 11.6% 9.0%
  Infection 8.0% 9.6% 7.6%
  Stomatitis 8.4% 6.8% 6.4%
  Mouth Ulceration 1.6% 3.2% 5.0%
  Flu Syndrome 3.2% 6.4% 5.0%
  Pharyngitis 3.2% 1.6% 4.3%
  Pain 4.0% 1.2% 4.3%
  Dyspepsia 2.0% 0 4.0%
  Infection Dental 4.0% 3.6% 3.8%
  Mucous Membrane Disorder 2.4% 0.8% 3.3%

The change in clinical attachment levels was similar across all study arms, suggesting that neither the vehicle nor ARESTIN® compromise clinical attachment.



REPORTS OF SUSPECTED ARESTIN SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Arestin. The information is not vetted and should not be considered as verified clinical evidence.

Possible Arestin side effects / adverse reactions in 31 year old male

Reported by a consumer/non-health professional from United States on 2011-11-11

Patient: 31 year old male

Reactions: Swelling Face, Tendon Rupture, Sunburn, Malaise, Arthralgia, Joint Swelling, Pericarditis, Insomnia, Chest Pain, Aortic Dilatation, Vision Blurred, Gait Disturbance, Feeling Abnormal

Adverse event resulted in: hospitalization

Suspect drug(s):
Arestin



Possible Arestin side effects / adverse reactions in 31 year old male

Reported by a consumer/non-health professional from United States on 2011-11-18

Patient: 31 year old male

Reactions: Swelling Face, Tendon Rupture, Sunburn, Malaise, Pericarditis, Arthralgia, Joint Swelling, Chest Pain, Insomnia, Vision Blurred, Aortic Dilatation, Gait Disturbance, Feeling Abnormal

Suspect drug(s):
Arestin



See index of all Arestin side effect reports >>

Drug label data at the top of this Page last updated: 2014-01-02

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2015