NEWS HIGHLIGHTSMedia Articles Related to Arestin (Minocycline)
Minocycline Show Benefits In Children With Inherited Cause Of Intellectual Disability And Autism
Source: Multiple Sclerosis News From Medical News Today [2013.04.10]
The antibiotic drug minocycline yields "modest" but meaningful improvements in functioning and mood for children with fragile X syndrome (FXS), reports a study in the April Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health...
Published Studies Related to Arestin (Minocycline)
Minocycline benefits negative symptoms in early schizophrenia: a randomised
double-blind placebo-controlled clinical trial in patients on standard treatment. [2012]
The onset and early course of schizophrenia is associated with subtle loss of
grey matter which may be responsible for the evolution and persistence of
symptoms such as apathy, emotional blunting, and social withdrawal...
Results of a phase II placebo-controlled randomized trial of minocycline in acute
spinal cord injury. [2012]
Preclinical studies have attributed neuroprotective properties to the antibiotic
minocycline... Although this study does not establish the efficacy of
minocycline in spinal cord injury the findings are encouraging and warrant
further investigation in a multi-centre phase III trial.
Minocycline-EDTA lock solution prevents catheter-related bacteremia in hemodialysis. [2011.10]
There is growing concern about the development of antibacterial resistance with the use of antibiotics in catheter lock solutions...
Minocycline treatment for HIV-associated cognitive impairment: results from a randomized trial. [2011.09.20]
OBJECTIVE: We conducted a study of minocycline to assess its safety, tolerability, and efficacy for the treatment of HIV-associated cognitive impairment... CONCLUSION: Minocycline was safe and well-tolerated in individuals with HIV-associated cognitive impairment, but cognitive improvement was not observed. Classification of evidence. This interventional study provides Class II evidence for the safety, tolerability, and efficacy of minocycline for the treatment of HIV-associated cognitive impairment.
Clinical and biochemical efficacy of minocycline in nonsurgical periodontal therapy: a randomized controlled pilot study. [2011.06]
The present study evaluated the effects of systemic minocycline on clinical and biochemical parameters of chronic periodontitis, which is a common inflammatory disorder of the periodontium initiated by the presence of bacteria in the gingival sulcus...
Clinical Trials Related to Arestin (Minocycline)
Minocycline Study in Non Small Cell Lung Cancer (NSCLC) Patients for Chemoradiation Therapy [Recruiting]
The goal of this clinical research study is to learn if minocycline can reduce the side
effects reported by patients with non small cell lung cancer (NSCLC) who are receiving
chemoradiation therapy. In this study, minocycline will be compared to a placebo.
Minocycline is an antibiotic that may help to reduce side effects of chemoradiation therapy.
A placebo is not a drug. It looks like the study drug but is not designed to treat any
disease or illness. It is designed to be compared with a study drug to learn if the study
drug has any real effect.
A Phase II Study of Minocycline and Armodafinil for Reducing the Symptom Burden Produced by Chemoradiation Treatment for Esophageal Cancer [Not yet recruiting]
The goal of this clinical research study is to compare armodafinil and minocycline when
given alone or in combination to learn which is better for controlling side effects of
chemoradiation treatment for esophageal cancer (such as fatigue, pain, disturbed sleep, lack
of appetite, and drowsiness).
Armodafinil is designed to prevent excessive sleepiness.
Minocycline is an antibiotic, which may help to reduce multiple symptoms.
In this study, you may receive a placebo. A placebo is not a drug. It looks like the study
drug but is not designed to treat any disease or illness. It is designed to be compared
with a study drug to learn if the study drug has any real effect.
Minocycline Study in Pancreatic Cancer Patients [Not yet recruiting]
The goal of this clinical research study is to learn if minocycline can reduce the side
effects of chemotherapy in patients with pancreatic cancer. In this study, minocycline will
be compared to a placebo.
Minocycline is an antibiotic that may help to reduce side effects of chemotherapy.
A placebo is not a drug. It looks like the study drug, but it is not designed to treat any
disease or illness. It is designed to be compared with a study drug to learn if the study
drug has any real effect.
A Study for Reducing Symptom Burden Produced by Chemoradiation Treatment for Non Small Cell Lung Cancer by Minocycline and Armodafinil [Recruiting]
The goal of this clinical research study is to compare armodafinil and minocycline when
given alone or in combination to learn which is better for controlling symptoms, such as the
side effects of chemoradiation, when given to treat lung cancer.
Adjunctive Minocycline in Clozapine Treated Schizophrenia Patients [Recruiting]
Schizophrenia is a devastating and costly illness. One-third to one-half of people with
schizophrenia do not respond to the most current drugs leaving clozapine as the best
alternative for treatment. However, over 60% of people treated with clozapine continue to
have persistent symptoms and cognitive impairments. Little data is available to support
evidence-based recommendations to guide clinicians in treating these patients. Preliminary
data has suggested that adjunct treatment with minocycline may offer robust symptom
improvement in patients with schizophrenia, including those taking clozapine. Minocycline
has had interesting effects; including suggesting it may have a significant role in
treatment of neurologic and psychiatric disorders. Minocycline is currently available
generically; its side effects are well-described and minimal. The proposed double-blind
treatment study seeks to demonstrate that adjunctive minocycline offers patients superior
efficacy for persistent positive symptoms, cognitive impairments, and/or other components of
schizophrenia pathology. This knowledge could lead to the more effective treatment of
patients with schizophrenia. The research itself may lead to a better understanding of the
pathophysiology of positive symptoms and cognitive impairments, which could contribute to
improved treatments in the future.
Reports of Suspected Arestin (Minocycline) Side Effects
Tooth Abscess (3),
Intentional Drug Misuse (3),
Tendon Rupture (2),
Malaise (2),
Chest Pain (2),
Swelling Face (2),
Sunburn (2),
Pericarditis (2),
Joint Swelling (2),
Arthralgia (2), more >>
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