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Aranesp (Erythropoiesis Stimulating Protein) - Drug Interactions, Contraindications, Overdosage, etc

 
 



DRUG INTERACTIONS

No formal drug interaction studies have been conducted with Aranesp.

OVERDOSAGE

Aranesp overdosage can cause hemoglobin levels above the desired level, which should be managed with discontinuation or reduction of Aranesp dosage and/or with phlebotomy, as clinically indicated [see Pharmacodynamics ]. Cases of severe hypertension have been observed following overdose with ESAs [see Warnings and Precautions].

CONTRAINDICATIONS

Aranesp is contraindicated in patients with:

  • Uncontrolled hypertension [see Warnings and Precautions ].
  • Pure red cell aplasia (PRCA) that begins after treatment with Aranesp or other erythropoietin protein drugs [see Warnings and Precautions].
  • Serious allergic reactions to Aranesp [see Warnings and Precautions].

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