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Aralast ( Alpha 1-Antitrypsin) - Published Studies


Aralast Related Published Studies

Well-designed clinical trials related to Aralast (Alpha 1-Antitrypsin)

The fibrinogen cleavage product Aalpha-Val360, a specific marker of neutrophil elastase activity in vivo. [2011.08]

Retinoid treatment of Emphysema in Patients on the Alpha-1 International Registry. The REPAIR study: study design, methodology and quality control of study assessments. [2010.12]

Pharmacokinetic comparability of Prolastin(R)-C to Prolastin(R) in alpha-antitrypsin deficiency: a randomized study. [2010.09.30]

Exploring the role of CT densitometry: a randomised study of augmentation therapy in alpha1-antitrypsin deficiency. [2009.06]

Prevalence of alpha-1 antitrypsin deficiency in poorly controlled asthma--results from the ALA-ACRC low-dose theophylline trial. [2007.10]

Alpha-1-antitrypsin replacement therapy: current status. [2006.03]

Multi-center study: the biochemical efficacy, safety and tolerability of a new alpha1-proteinase inhibitor, Zemaira. [2006.03]

Safety and efficacy of recombinant alpha(1)-antitrypsin therapy in cystic fibrosis. [2006.02]

Short-term variability of biomarkers of proteinase activity in patients with emphysema associated with type Z alpha-1-antitrypsin deficiency. [2005.05.31]

Emphysema in alpha1-antitrypsin deficiency: does replacement therapy affect outcome? [2005]

Prevalence of alpha1-antitrypsin phenotypes in patients with IgA nephropathy. [2004.12]

Protease inhibitors alpha1-antitrypsin and ilomastat are not ototoxic in the chinchilla. [2003.10]

Peripheral deposition of alpha1-protease inhibitor using commercial inhalation devices. [2003.08]

Biochemical efficacy and safety of a new pooled human plasma alpha(1)-antitrypsin, Respitin. [2002.07]

Alpha1-antitrypsin deficiency: a position statement of the Canadian Thoracic Society. [2001.03]

Alpha-1 proteinase inhibitor (a1PI) for preventing chronic lung disease in preterm infants. [2001]

Dyspnea management in alpha-1 antitrypsin deficiency: effect of oxygen administration. [2000.11]

Feasibility of a clinical trial of augmentation therapy for alpha(1)-antitrypsin deficiency. The Alpha 1-Antitrypsin Deficiency Registry Study Group. [2000.03]

A randomized clinical trial of alpha(1)-antitrypsin augmentation therapy. [1999.11]

Functional and antigenic concentrations of alpha-1-proteinase inhibitor after administration for the prevention of chronic lung disease of prematurity. [1999.09]

alpha1-Proteinase inhibitor therapy for the prevention of chronic lung disease of prematurity: a randomized, controlled trial. [1998.01]

Progress of emphysema in severe alpha 1-antitrypsin deficiency as assessed by annual CT. [1997.09]

The effect of inhaled glucocorticosteroids in emphysema due to alpha1-antitrypsin deficiency. [1997.05]

Efficacy of systemically administered acetylsalicylic acid plus scaling on periodontal health and elastase-alpha 1-proteinase inhibitor in gingival crevicular fluid. [1996.03]

Effects of low dose methotrexate therapy on the concentration and the glycosylation of alpha 1-acid glycoprotein in the serum of patients with rheumatoid arthritis: a longitudinal study. [1994.12]

Well-designed clinical trials possibly related to Aralast (Alpha 1-Antitrypsin)

Impact of non-linear smoking effects on the identification of gene-by-smoking interactions in COPD genetics studies. [2011.10]

Perioperative use of a neutrophil elastase inhibitor in video-assisted thoracoscopic oesophagectomy for cancer. [2011.07]

Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide. [2010.12.22]

Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation. [2010.04.05]

Pro- and prebiotic supplementation induces a transient reduction in hemoglobin concentration in infants. [2009.11]

Pro- and Prebiotic Supplementation Induces a Transient Reduction in Hemoglobin Concentration in Infants. [2009.07.28]

Alterations in the human lung proteome with lipopolysaccharide. [2009.05.11]

The benefit of daily photoprotection. [2008.05]

No effects of probiotics on atopic dermatitis in infancy: a randomized placebo-controlled trial. [2006.07]

Rectal bleeding in infancy: clinical, allergological, and microbiological examination. [2006.04]

Effects of ulinastatin on pulmonary artery pressure during abdominal aortic aneurysmectomy. [2006.02]

Probiotic effects on faecal inflammatory markers and on faecal IgA in food allergic atopic eczema/dermatitis syndrome infants. [2005.02]

Residues 34-39 in the thyrotropin receptor are not the target of autoantibodies from sera of patients with Graves' disease. [2004.08]

Tissue trauma after vaginal hysterectomy and colporrhaphy versus abdominal hysterectomy: a randomised controlled study. [2004.08]

Subantimicrobial dose doxycycline efficacy as a matrix metalloproteinase inhibitor in chronic periodontitis patients is enhanced when combined with a non-steroidal anti-inflammatory drug. [2004.03]

Effect of early enteral nutrition on intestinal permeability, intestinal protein loss, and outcome in dogs with severe parvoviral enteritis. [2003.11]

A pilot study of all-trans-retinoic acid for the treatment of human emphysema. [2002.03.01]

The value of routine antibiotic prophylaxis in mandibular third molar surgery: acute-phase protein levels as indicators of infection. [2001.06]

Concentration of the complement activation product, acylation-stimulating protein, is related to C-reactive protein in patients with type 2 diabetes. [2001.03]

Comparison of postoperative acute-phase reactants in patients who underwent laparoscopic v open cholecystectomy: a randomized study. [2000.10]

Tension-free hernia repair is associated with an increase in inflammatory response markers against the mesh. [2000.09]

A randomized cross-over study on the effects of levonorgestrel- and desogestrel-containing oral contraceptives on the anticoagulant pathways. [2000.07]

Treatment of iron deficiency anemia and associated protein-losing enteropathy in children. [2000.01]

Troglitazone reduces hyperglycaemia and selectively acute-phase serum proteins in patients with Type II diabetes. [1999.12]

Activation of the contact system of coagulation does not contribute to the hemostatic imbalance in hypertriglyceridemia. [1999.10]

Minimal access surgery for cholelithiasis induces an attenuated acute phase response. [1999.09]

Reducing neutrophil elastase-induced lung injury. [1999.03]

Inhaled budesonide in ventilator-dependent preterm infants: a randomized, double-blind pilot study. [1999]

Activation of the protein C system during cardiopulmonary bypass with and without aprotinin. [1998.12]

Peritoneal lavage with aprotinin in patients with severe acute pancreatitis. Effects on plasma and peritoneal levels of trypsin and leukocyte proteases and their major inhibitors. [1998.08]

Steroids in the hemolytic uremic syndrome. [1998.02]

Biocompatibility reflected by haemostasis variables during cardiopulmonary bypass using heparin-coated circuits. [1997.08]

Probiotics: a novel approach in the management of food allergy. [1997.02]

Metabolic responses after laparoscopic or open hernia repair. [1996.06]

[Low-dose polyethylene glycol 4000: digestive effects. Randomized double-blind study in healthy subjects] [1996]

Contribution of secretory leukocyte proteinase inhibitor to the antiprotease defense system of the peripheral lung: effect of ozone-induced acute inflammation. [1995.11]

The acute phase protein response in patients receiving subcutaneous IL-6. [1995.10]

Ozone exposure has both a priming effect on allergen-induced responses and an intrinsic inflammatory action in the nasal airways of perennially allergic asthmatics. [1995.05]

Colchicine treatment of primary sclerosing cholangitis. [1995.04]

Immunoreactive interleukin-6 and acute phase proteins as prognostic factors in multiple myeloma. Finnish Leukemia Group. [1995.02.01]

Enteric protein loss and intestinal permeability changes in children during acute shigellosis and after recovery: effect of zinc supplementation. [1994.12]

Erythropoietin response and route of administration. [1994.05]

Local serum application: restoration of sufficient host defense in human peritonitis. [1994.01]

Acute effects of a single dose of porcine surfactant on patients with the adult respiratory distress syndrome. [1994.01]

Effects of dexamethasone on chemotactic activity and inflammatory mediators in tracheobronchial aspirates of preterm infants at risk for chronic lung disease. [1993.06]

The effect of bed rest and intra-articular steroids on the acute phase response in rheumatoid arthritis. [1993.01]

The effect of epidural blockade on postoperative hypercoagulability following abdominal aortic bypass surgery. [1992.11]

Changes in coagulation and anticoagulation in women taking low-dose triphasic oral contraceptives: a controlled comparative 12-month clinical trial. [1992.11]

In vivo clearance and elimination of nine marker substances during hemofiltration with different membranes. [1992.07]

Acute phase reactants and interleukin 6 after total hip replacement. Effects of high dose corticosteroids. [1992.06]

The influence of tourniquet ischaemia on post-operative degranulation of polymorphonuclear granulocytes. [1992.05]

[The value of plasma proteins in the postoperative follow-up of surgery on gastrointestinal tumors: the effect of nutritional support] [1992.03]

Controlled trial comparing two types of enteral nutrition in treatment of active Crohn's disease: elemental versus polymeric diet. [1991.12]

Attenuation of intra-operative surgical stress response has no influence on post-operative degranulation of polymorphonuclear granulocytes. [1991.09]

A single intravenous infusion of gamma globulin as compared with four infusions in the treatment of acute Kawasaki syndrome. [1991.06.06]

Effect of dexamethasone on pulmonary inflammation and pulmonary function of ventilator-dependent infants with bronchopulmonary dysplasia. [1991.05]

Effects of ethinyl oestradiol/polyoestradiol phosphate and estramustine phosphate on some proteins related to haemostasis in prostatic carcinoma patients. [1991]

Comparison of the clinical performance, contraceptive efficacy and acceptability of levonorgestrel-releasing IUD and Norplant-2 implants in China. [1990.05]

Comparative study on the effect of Diane and Microgynon 50 contraceptive on the haemostatic mechanisms in Chinese subjects. [1990.04]

Total enteral nutrition versus total parenteral nutrition after major torso injury: attenuation of hepatic protein reprioritization. [1988.08]

Inhibition of post-traumatic septic proteolysis and ureagenesis and stimulation of hepatic acute-phase protein production by branched-chain amino acid TPN. [1988.08]

Blood coagulation in postmenopausal women given estrogen treatment: comparison of transdermal and oral administration. [1988.02]

Multicentre clinical trial of low volume fresh frozen plasma therapy in acute pancreatitis. [1987.10]

Other research related to Aralast (Alpha 1-Antitrypsin)

Effects of Prolastin C (Plasma-Derived Alpha-1 Antitrypsin) on the acute inflammatory response in patients with ST-segment elevation myocardial infarction (from the VCU-alpha 1-RT pilot study). [2015]

Relation of functional characteristics and serum alpha-1-antitrypsin (AAT) concentration in patients with PiMM phenotype and chronic obstructive pulmonary disease (COPD). [2011.12]

ANCA-associated vasculitis is linked to carriage of the Z allele of alpha antitrypsin and its polymers. [2011.10]

Phase 2 Clinical Trial of a Recombinant Adeno-Associated Viral Vector Expressing alpha(1)-Antitrypsin: Interim Results. [2011.10]

A Review of Alpha-1 Antitrypsin Deficiency. [2011.09.29]

Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury. [2011.08]

Oxidation of Z alpha1-antitrypsin by cigarette smoke induces polymerization: a novel mechanism of early-onset emphysema. [2011.08]

The prevalence of alpha-1 antitrypsin deficiency in Ireland. [2011.07.13]

The role of proteases, endoplasmic reticulum stress and SERPINA1 heterozygosity in lung disease and alpha-1 anti-trypsin deficiency. [2011.06]

Efficacy of alpha1-antitrypsin augmentation therapy in conditions other than pulmonary emphysema. [2011.04.12]

[Clinical trial endpoints in alpha-1-antitrypsin deficiency: interdisciplinary aspects]. [2011.04]

Matrix metalloproteinase-9 predicts pulmonary status declines in alpha1-antitrypsin deficiency. [2011.03.23]

The role of augmentation therapy in alpha-1 antitrypsin deficiency. [2011.03]

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