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Antivenin (Latrodectus Mactans Antivenom) - Summary

 

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ANTIVENIN SUMMARY

Antivenin (Latrodectus mactans) is a sterile, non-pyrogenic preparation derived by drying a frozen solution of specific venom-neutralizing globulins obtained from the blood serum of healthy horses immunized against venom of black widow spiders (Latrodectus mactans). It is standardized by biological assay on mice, in terms of one dose of antivenin neutralizing the venom in not less than 6000 mouse LD50 of Latrodectus mactans. Thimerosal (mercury derivative) 1:10,000 is added as a preservative. When constituted as specified, it is opalescent, ranging in color from light (straw) to very dark (iced tea), and contains not more than 20.0 percent of solids.

Antivenin (Latrodectus mactans) is used to treat patients with symptoms due to bites by the black widow spider (Latrodectus mactans). Early use of the Antivenin is emphasized for prompt relief.

ANTIVENIN NEWS HIGHLIGHTS

Media Articles Related to Antivenin (Latrodectus Mactans)

Spider Bites: Black Widow and Brown Recluse
Source: MedicineNet Anaphylaxis Specialty [2008.05.27]

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Published Studies Related to Antivenin (Latrodectus Mactans)

Monospecific antivenin therapy in Russell's viper bite. [1994.06]

Utility of scorpion antivenin vs prazosin in the management of severe Mesobuthus tamulus (Indian red scorpion) envenoming at rural setting. [2007.01]

A large single-center experience with treatment of patients with crotalid envenomations: outcomes with and evolution of antivenin therapy. [2006.12]

Kenyan medicinal plants used as antivenin: a comparison of plant usage. [2006.02.01]

Kenyan medicinal plants used as antivenin: a comparison of plant usage. [2006.02.01]

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Clinical Trials Related to Antivenin (Latrodectus Mactans)

The Efficacy and Safety of Aracmyn in Patients With Systemic Latrodectism [Completed]

Improving Safety of Antivenom in People Bitten by Snakes [Completed]

The Efficacy of Crotaline Fab Antivenom for Copperhead Snake Envenomations [Recruiting]

Black Widow Spider Antivenin for Patients With Systemic Latrodectism [Not yet recruiting]

Establishment of Natural History of Scorpion Envenomation [Completed]

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Page last updated: 2008-05-27

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