Amphetamine (Amphetamine) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

Cardiovascular:    Palpitations, tachycardia, elevation of blood pressure. There have been isolated reports of cardiomyopathy associated with chronic amphetamine use.

Central Nervous System:    Psychotic episodes at recommended doses (rare), overstimulation, restlessness, dizziness, insomnia, euphoria, dyskinesia, dysphoria, tremor, headache, exacerbation of motor and phonic tics and Tourette's syndrome.

Gastrointestinal:    Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances. Anorexia and weight loss may occur as undesirable effects when amphetamines are used for other than the anorectic effect.

Allergic:    Urticaria.

Endocrine:    Impotence, changes in libido.

DRUG ABUSE AND DEPENDENCE

Dextroamphetamine sulfate is a Schedule II controlled substance.

Amphetamines have been extensively abused. Tolerance, extreme psychological dependence, and severe social disability have occurred. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with amphetamines include severe dermatoses, marked insomnia, irritability, hyperactivity, and personality changes. The most severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia. This is rare with oral amphetamines.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO AMPHETAMINE

Possible Amphetamine side effects / adverse reactions in 20 year old male

Reported by a individual with unspecified qualification on 2007-02-05

Patient: 20 year old male

Reactions: Road Traffic Accident, Balance Disorder, Insomnia, Disturbance in Attention, Depressed Level of Consciousness, Tremor, Substance Abuse

Suspect drug(s):
Substitol Retard Kapseln
    Administration route: Oral
    Indication: Drug Withdrawal Maintenance Therapy

Amphetamine
    Administration route: Oral
    Indication: Drug Abuser

Hypnotics and Sedatives
    Administration route: Oral
    Indication: Drug Abuser

Cannabis
    Administration route: Oral
    Indication: Drug Abuser

Cocaine
    Administration route: Oral
    Indication: Drug Abuser

Possible Amphetamine side effects / adverse reactions in 50 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2007-10-03

Patient: 50 year old male

Reactions: Psychotic Disorder, Drug Dependence, Hallucination

Suspect drug(s):
Fentanyl
    Indication: Drug USE FOR Unknown Indication

Valium
    Indication: Drug USE FOR Unknown Indication

Antidepressants
    Indication: Drug USE FOR Unknown Indication

Percocet
    Indication: Drug USE FOR Unknown Indication

Amphetamine
    Indication: Drug USE FOR Unknown Indication