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Amitiza (Lubiprostone) - Published Studies

 
 



Amitiza Related Published Studies

Well-designed clinical trials related to Amitiza (Lubiprostone)

Efficacy and safety of oral lubiprostone in constipated patients with or without irritable bowel syndrome: a randomized, placebo-controlled and dose-finding study. [2011.06]

Efficacy and safety of lubiprostone in patients with chronic constipation. [2010.04]

Lubiprostone neither decreases gastric and small-bowel transit time nor improves visualization of small bowel for capsule endoscopy: a double-blind, placebo-controlled study. [2009.11]

Clinical trial: lubiprostone in patients with constipation-associated irritable bowel syndrome--results of two randomized, placebo-controlled studies. [2009.02.01]

Effect of a chloride channel activator, lubiprostone, on colonic sensory and motor functions in healthy subjects. [2009.02]

Single-dose lubiprostone along with split-dose PEG solution without dietary restrictions for bowel cleansing prior to colonoscopy: a randomized, double-blind, placebo-controlled trial. [2008.09]

Single-Dose Lubiprostone Along With Split-Dose PEG Solution Without Dietary Restrictions for Bowel Cleansing Prior to Colonoscopy: A Randomized, Double-Blind, Placebo-Controlled Trial. [2008.08.05]

Clinical trial: phase 2 study of lubiprostone for irritable bowel syndrome with constipation. [2008.04]

Multicenter, 4-week, double-blind, randomized, placebo-controlled trial of lubiprostone, a locally-acting type-2 chloride channel activator, in patients with chronic constipation. [2008.01]

Lubiprostone, a locally acting chloride channel activator, in adult patients with chronic constipation: a double-blind, placebo-controlled, dose-ranging study to evaluate efficacy and safety. [2007.06.01]

Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteers. [2006.05]

Well-designed clinical trials possibly related to Amitiza (Lubiprostone)

MiraLAX is not as effective as GoLytely in bowel cleansing before screening colonoscopies. [2011.04]

Other research related to Amitiza (Lubiprostone)

A critical appraisal of lubiprostone in the treatment of chronic constipation in the elderly. [2013]

Lubiprostone does not influence visceral pain thresholds in patients with irritable bowel syndrome. [2011.10]

Long-term safety and effectiveness of lubiprostone, a chloride channel (ClC-2) activator, in patients with chronic idiopathic constipation. [2011.09]

Lubiprostone for the treatment of adults with constipation and irritable bowel syndrome. [2011.06]

Lubiprostone for the treatment of opioid-induced bowel dysfunction. [2011.04]

Lubiprostone reverses the inhibitory action of morphine on mucosal secretion in human small intestine. [2011.02]

Lubiprostone: evaluation of the newest medication for the treatment of adult women with constipation-predominant irritable bowel syndrome. [2010.10.27]

Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype. [2010.09.15]

Lubiprostone used with polyethylene glycol in diabetic patients enhances colonoscopy preparation quality. [2010.07.16]

Lubiprostone reverses the inhibitory action of morphine on intestinal secretion in guinea pig and mouse. [2010.07]

Use of the chloride channel activator lubiprostone for constipation in adults with cystic fibrosis: a case series. [2010.03]

Efficacy and safety of lubiprostone in patients with chronic constipation. [2010]

Lubiprostone: in constipation-predominant irritable bowel syndrome. [2009.06.18]

Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon. [2009.04]

Lubiprostone: chronic constipation and irritable bowel syndrome with constipation. [2009.01]

Lubiprostone: in constipation-predominant irritable bowel syndrome. [2009]

Lubiprostone for constipation and irritable bowel syndrome with constipation. [2008.12]

Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice. [2008.11]

Lubiprostone--a novel treatment for irritable bowel syndrome with constipation. [2008.09]

Clinical pharmacology of lubiprostone, a chloride channel activator in defecation disorders. [2008.08]

Lubiprostone for chronic idiopathic constipation and irritable bowel syndrome with constipation. [2008.08]

Lubiprostone: a novel treatment for chronic constipation. [2008]

Lubiprostone: a new drug for the treatment of chronic idiopathic constipation. [2007.09]

Lubiprostone: a chloride channel activator for treatment of chronic constipation. [2007.06]

Lubiprostone: a chloride channel activator. [2007.04]

Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone. [2007.02]

Lubiprostone: chloride channel activator for chronic constipation. [2006.12]

Lubiprostone. [2006]

Lubiprostone. [2005.05]

Other possibly related research studies

Development of drugs for gastrointestinal motor disorders: translating science to clinical need. [2008.03]

Gateways to clinical trials. [2007.11]

Constipation: evaluation and treatment of colonic and anorectal motility disorders. [2007.09]

Fresh perspectives in chronic constipation and other functional bowel disorders. [2007.06]

Cancer-related constipation. [2007.07]

Novel and alternative therapies for childhood constipation. [2007.06]

Constipation in long-term care. [2007.05]

New drugs 07, part I. [2007.02]

Activation of type-2 chloride channels: a novel therapeutic target for the treatment of chronic constipation. [2007.01]

Gateways to clinical trials. [2006.09]

Defecation disorders: neuromuscular aspects and treatment. [2006.08]

Chronic constipation: let symptom type and severity direct treatment. [2006.07]

Gateways to clinical trials. [2006.01]

Gateways to clinical trials. [2005.05]

Gateways to clinical trials. [2003.07]

A synthetic prostone activates apical chloride channels in A6 epithelial cells. [2008.08]

Pathogenesis and management of irritable bowel syndrome. [2009.01]

Constipation in the elderly: management strategies. [2009]

Constipation: evaluation and treatment of colonic and anorectal motility disorders. [2009.01]

Pharmacologic treatment of constipation: what is new? [2008.12]

Enteric nervous system: sensory physiology, diarrhea and constipation. [2010.03]

Review article: new receptor targets for medical therapy in irritable bowel syndrome. [2010.01]

The use of novel promotility and prosecretory agents for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation. [2009.05]

Linaclotide, a synthetic guanylate cyclase C agonist, for the treatment of functional gastrointestinal disorders associated with constipation. [2011.06]

Treatment of irritable bowel syndrome. [2011.06]

Review article: the treatment of functional abdominal bloating and distension. [2011.05]

Current and future therapies for chronic constipation. [2011.02]

A review of laxative therapies for treatment of chronic constipation in older adults. [2010.12]

Peripherally acting therapies for the treatment of irritable bowel syndrome. [2011.03]

Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis. [2011.02]

[New therapeutical approaches for treatment of irritable bowel syndrome]. [2010.08]

Pharmacologic management of chronic constipation. [2010.09]

Gastroduodenal mucosal defense. [2010.11]

Emerging pharmacologic therapies for irritable bowel syndrome. [2010.10]

[New drugs for the treatment of constipation]. [2010.07]

Linaclotide in the management of gastrointestinal tract disorders. [2012]

Evaluation of harm in the pharmacotherapy of irritable bowel syndrome. [2012]

Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis. [2011]

New treatment targets for the management of irritable bowel syndrome. [2014]

Metabolic and toxicological considerations for the latest drugs used to treat irritable bowel syndrome. [2013]

Clinical trials in irritable bowel syndrome: a review. [2013]

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