Media Articles Related to Americaine (Benzocaine)
Patients With Sleep Apnea Undergoing Joint Replacement Have Improved Outcomes With Regional Anesthesia
Source: Arthritis / Rheumatology News From Medical News Today [2013.05.07]
Using regional anesthesia instead of general anesthesia in patients with sleep apnea undergoing total joint replacement decreases major complications by 17%, according to a study published online, ahead of print, in the journal Regional Anesthesia and Pain Medicine...
Lower Rates Of Complications In Hip And Knee Replacement Using Regional Anesthesia Technique
Source: Arthritis / Rheumatology News From Medical News Today [2013.05.03]
A highly underutilized anesthesia technique called neuraxial anesthesia, also known as spinal or epidural anesthesia, improves outcomes in patients undergoing hip or knee replacement, according to a new study by researchers at Hospital for Special Surgery...
General Anesthesia Not Linked to Raised Risk for Dementia
Source: MedicineNet Dementia Specialty [2013.05.02]
Title: General Anesthesia Not Linked to Raised Risk for Dementia
Category: Health News
Created: 5/1/2013 12:35:00 PM
Last Editorial Review: 5/2/2013 12:00:00 AM
Success Rates Of Turning Breech Babies Increased By Anesthesia, Delivery Costs Reduced
Source: Pain / Anesthetics News From Medical News Today [2013.04.22]
When a baby is in the breech position at the end of pregnancy, obstetricians can sometimes turn the baby head-down to enable a safer vaginal birth. In the past, women were not given anesthesia during the turning procedure, which requires the physician to push on the woman's abdomen while monitoring the baby with ultrasound...
Development Of Wisdom Teeth In Children May Be Affected By Dental Anesthesia
Source: Dentistry News From Medical News Today [2013.04.05]
Researchers from Tufts University School of Dental Medicine have discovered a statistical association between the injection of local dental anesthesia given to children ages two to six and evidence of missing lower wisdom teeth...
Published Studies Related to Americaine (Benzocaine)
Double-blind comparison of two types of benzocaine lozenges for the treatment of acute pharyngitis. 
In a reference-controlled double-blind trial in patients with acute pharyngitis the effects of a newly developed lozenge containing 8 mg of benzocaine (p-aminobenzoic acid ethyl ester, CAS 94-09-7) were compared with those of an identically dosed commercial pastille... The application of the benzocaine lozenges was statistically non-inferior to the use of the pastilles.
Topical anesthesia for rubber dam clamp placement in sealant placement: comparison of lidocaine/prilocaine gel and benzocaine. [2009.09]
PURPOSE: The purpose of this prospective study was to compare the efficacy of Oraqix to benzocaine while placing a rubber dam clamp during sealant placement on children... CONCLUSIONS: Application of Oraqix did not reduce discomfort when compared to benzocaine in this small sample size. Oraqix was more effective than benzocaine in the age group 9 and older. A larger sample size is needed to determine its efficacy in children younger than 9years old.
A study of benzocaine gel dosing for toothache. 
CONCLUSION: The improved dosing directions resulted in a high percentage of subjects self-applying an appropriate amount of benzocaine gel or matching placebo. The label and study methodology appear suitable for a pivotal dose-response study in subjects with toothache pain. While the current study was not statistically powered to make firm efficacy conclusions, 20% benzocaine gel appeared more efficacious than placebo, providing a rapid onset of pain relief and a relatively long duration of action.
Prospective randomized study of viscous lidocaine versus benzocaine in a GI cocktail for dyspepsia. [2004.07]
We hypothesized that Benzocaine (Hurricaine) would work as quickly and effectively as viscous Lidocaine in this preparation. This was a prospective randomized, single-blinded comparison between Benzocaine and Lidocaine as the topical anesthetic in a gastrointestinal (GI) cocktail... There were no adverse outcomes in either group.
Efficacy and tolerability of an intraoral benzocaine patch in the relief of spontaneous toothache pain. 
CONCLUSION: Although the results of the present study were promising, further research on this novel delivery system of benzocaine is warranted to firmly establish efficacy in patients with spontaneous toothache pain.
Clinical Trials Related to Americaine (Benzocaine)
Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel [Recruiting]
The project is a study comparing the effectiveness of two topical anesthetics for control of
pain associated with dental needle insertion in the palatal mucosa. A standard dental
topical anesthetic (20% benzocaine) will serve as an "active" control and will be compared
to a combination topical anesthetic, consisting of 20% lidocaine, 4% tetracaine and 2%
phenylephrine (TAC Alternate Gel, Compounding Arts Pharmacy, Lafayette, LA).
Use of Topical Benzocaine for Analgesia in Lingual Frenotomy of the Newborn [Not yet recruiting]
Frenotomy of tongue-tie is commonly performed to resolve breastfeeding difficulties, eg
maternal nipple pain and infant's latching difficulties. The procedure carries minor
discomfort for the infants. It is not known whether the use of topical benzocaine, a very
bitter tasting material' applied to the tongue-tie would decrease the length of cry. We will
measure the duration of crying in infants treated with topical benzocaine to the duration in
those not treated with the mediation.
Benzocaine Gel Toothache Dose-Response Study [Recruiting]
To evaluate the efficacy and safety of benzocaine gel products for the relief of toothache
and to assess the subject's compliance with proposed label directions.
Maintenance After Initiation of Nutrition TrAINing [Recruiting]
Obesity is the second leading cause of preventable deaths in the United States and is
associated with a wide range of diseases. In people who are obese, weight loss improves
blood pressure, dyslipidemia, glycemia, and arthritis symptoms; reduces medication use for
several disease processes; increases physical functioning; and enhances health-related
quality of life. The current study will evaluate a theoretically informed maintenance
intervention. If effective, this intervention could reduce the need for future clinic visits
to treat obesity and its many associated illnesses.
A Study to Investigate the Ability of GSK706769 to Maintain Clinical Remission After Withdrawal of Enbrel in Rheumatoid Arthritis Patients [Not yet recruiting]
The purpose of this study is to determine if GSK706769 can maintain clinical remission
established by Enbrel after withdrawal of Enbrel in rheumatoid arthritis patients.