NEWS HIGHLIGHTSMedia Articles Related to Americaine (Benzocaine)
Abdominal Surgery Without General Anesthesia
Source: GastroIntestinal / Gastroenterology News From Medical News Today [2009.11.04]
A recent review in Faculty of 1000 Medicine Reports, a publication in which clinicians highlight advances in medical practice, suggests regional pain relief could be used during abdominal surgery. In this review, Michael Schaefer recommends a new approach that can be performed without the need for general anaesthetics.
Anesthesia, Exertional Heat Deaths May Be Linked
Source: MedicineNet Hyperthermia Specialty [2009.10.26]
Title: Anesthesia, Exertional Heat Deaths May Be Linked
Category: Health News
Created: 10/23/2009 4:10:00 PM
Last Editorial Review: 10/26/2009
Anesthesia in Youngest Kids May be Linked to Learning Disabilities
Source: MedicineNet Hernia Specialty [2009.03.25]
Title: Anesthesia in Youngest Kids May be Linked to Learning Disabilities
Category: Health News
Created: 3/25/2009 2:00:00 AM
Last Editorial Review: 3/25/2009
Need For Emergency Airway Surgery For Hard-to-Intubate Patients Reduced
Source: Respiratory / Asthma News From Medical News Today [2009.11.18]
Be prepared, that old Boy Scout motto, is being applied with great success to operating room patients whose anatomy may make it difficult for physicians to help them breathe during surgery, Johns Hopkins researchers report in a new study. When patients undergo general anesthesia, they stop breathing on their own and anesthesiologists must quickly insert a tube into the airway as a first step in machine-assisted breathing.
New Technique For Injectable Facial Fillers Improves Comfort, Recovery
Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today [2009.10.29]
Less pain during injections for wrinkle-fighting facial fillers. Less swelling afterward. Less time in the office waiting for anesthesia to take effect. These and other benefits of a new injection technique that UT Southwestern Medical Center plastic surgeons are helping pioneer are outlined in the October issue of Plastic and Reconstructive Surgery.
Published Studies Related to Americaine (Benzocaine)
A study of benzocaine gel dosing for toothache. [2005]
CONCLUSION: The improved dosing directions resulted in a high percentage of subjects self-applying an appropriate amount of benzocaine gel or matching placebo. The label and study methodology appear suitable for a pivotal dose-response study in subjects with toothache pain. While the current study was not statistically powered to make firm efficacy conclusions, 20% benzocaine gel appeared more efficacious than placebo, providing a rapid onset of pain relief and a relatively long duration of action.
Prospective randomized study of viscous lidocaine versus benzocaine in a GI cocktail for dyspepsia. [2004.07]
We hypothesized that Benzocaine (Hurricaine) would work as quickly and effectively as viscous Lidocaine in this preparation. This was a prospective randomized, single-blinded comparison between Benzocaine and Lidocaine as the topical anesthetic in a gastrointestinal (GI) cocktail... There were no adverse outcomes in either group.
Efficacy and tolerability of an intraoral benzocaine patch in the relief of spontaneous toothache pain. [2003]
CONCLUSION: Although the results of the present study were promising, further research on this novel delivery system of benzocaine is warranted to firmly establish efficacy in patients with spontaneous toothache pain.
Efficacy of a wax containing benzocaine in the relief of oral mucosal pain caused by orthodontic appliances. [2002.10]
During orthodontic treatment, pain and discomfort of the oral mucosa can be experienced as a result of trauma from the appliances caused by increased friction between mucosal tissue and the surface of the brackets. Currently, orthodontists have few remedies to prevent or relieve this mucosal irritation...
Reducing children's injection pain: lidocaine patches versus topical benzocaine gel. [2001.01]
PURPOSE: The purpose of this study was to compare the effectiveness of lidocaine patches and topical anesthetic gel in reducing injection pain in children... CONCLUSIONS: A statistically significant decrease in observed verbal indicators of injection pain was found when the DentiPatch was used 20%: compared to a 1 minute application of topical anesthetic gel. However, no significant difference was found between the two study groups in either reported pain or observed pain-motor responses.
Clinical Trials Related to Americaine (Benzocaine)
Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel [Recruiting]
The project is a study comparing the effectiveness of two topical anesthetics for control of
pain associated with dental needle insertion in the palatal mucosa. A standard dental
topical anesthetic (20% benzocaine) will serve as an "active" control and will be compared
to a combination topical anesthetic, consisting of 20% lidocaine, 4% tetracaine and 2%
phenylephrine (TAC Alternate Gel, Compounding Arts Pharmacy, Lafayette, LA).
Benzocaine Gel Toothache Dose-Response Study [Recruiting]
To evaluate the efficacy and safety of benzocaine gel products for the relief of toothache
and to assess the subject's compliance with proposed label directions.
A Study to Investigate the Ability of GSK706769 to Maintain Clinical Remission After Withdrawal of Enbrel in Rheumatoid Arthritis Patients [Not yet recruiting]
The purpose of this study is to determine if GSK706769 can maintain clinical remission
established by Enbrel after withdrawal of Enbrel in rheumatoid arthritis patients.
Safety Oral Mucosa Evaluation - Acceptability With Odontological Follow up - Cepacol Canela Power [Completed]
To prove the safety, in normal conditions, of the odontological use formulation of the
product Cepacol Canela Power.
Can Tadalafil Maintain Erectile Function In Patients Treated With Radiotherapy For Prostate Cancer? [Terminated]
Because of the high incidence of post-radiation erectile dysfunction (ED), up to 72% after
external-beam radiotherapy, this patient category represents a most difficult therapeutic
challenge. Therefore, prevention of ED could be more effective than treatment. Tadalafil, a
new phosphodiesterase type 5 inhibitor, has been recently introduced. No studies have
investigated the efficacy of tadalafil in preventing ED in patients undergoing radiotherapy
for prostate cancer. Efficacy of tadalafil can last up to 36 hours after intake. This will
result in a prolonged and continuos enhancement of penile vascular responsiveness. This
randomized, double-blind, placebo-controlled study has been designed to evaluate the efficacy
of 20-mg of tadalafil administered for 12 months in maintaining erectile function of potent
patients undergoing external-beam radiotherapy for prostate cancer.
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