DOSAGE AND ADMINISTRATION
The dose of Ambien CR should be individualized.
Dosage in adults
The recommended dose of Ambien CR for adults is 12.5 mg once daily immediately before bedtime. The total Ambien CR dose should not exceed 12.5 mg per day.
Elderly or debilitated patients may be especially sensitive to the effects of zolpidem tartrate. Patients with hepatic insufficiency do not clear the drug as rapidly as normals. The recommended dose of Ambien CR in both of these patient populations is 6.25 mg once daily immediately before bedtime [see Warnings and Precautions].
Use with CNS depressants
Dosage adjustments may be necessary when Ambien CR is combined with other CNS depressant drugs because of the potentially additive effects [see Warnings and Precautions].
Ambien CR extended-release tablets should be swallowed whole, and not be divided, crushed, or chewed. The effect of Ambien CR may be slowed by ingestion with or immediately after a meal.
DOSAGE FORMS AND STRENGTHS
Ambien CR is available as extended-release tablets containing 6.25 mg or 12.5 mg of zolpidem tartrate for oral administration. Tablets are not scored.
Ambien CR 6.25 mg tablets are pink, round, bi-convex, and debossed with A~ on one side.
Ambien CR 12.5 mg tablets are blue, round, bi-convex, and debossed with A~ on one side.