NEWS HIGHLIGHTSMedia Articles Related to Alvesco (Ciclesonide Inhalation)
Asthma Combo Seems Less Influenced by Genes (HealthDay)
Source: Y! Health Asthma News [2009.11.19]
HealthDay - THURSDAY, Nov. 19 (HealthDay News) -- People's genetic makeup has
been shown to affect how they respond to asthma medications, but a new
study finds that many people respond well to a particular combination
treatment regardless of their genes.
Annals Of Allergy, Asthma And Immunology To Be Published By Elsevier
Source: Allergy News From Medical News Today [2009.11.18]
Elsevier is pleased to announce that beginning with Volume 104 (2010) it will assume publication of the Annals of Allergy, Asthma & Immunology, the official journal of the American College of Allergy, Asthma & Immunology (ACAAI). The i>Annals of Allergy, Asthma & Immunology, published since 1942, will continue under the leadership of Editor Gailen D. Marshall, MD, PhD and a distinguished editorial board.
Folic Acid Late in Pregnancy Tied to Asthma in Kids
Source: MedicineNet Asthma Specialty [2009.11.16]
Title: Folic Acid Late in Pregnancy Tied to Asthma in Kids
Category: Health News
Created: 11/13/2009 2:10:00 PM
Last Editorial Review: 11/16/2009
New Research Shows Over-use Of Asthma Rescue Inhalers Substantially Reduced Through Pharmacist-initiated Physician Intervention
Source: Respiratory / Asthma News From Medical News Today [2009.11.13]
Research presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting shows that an intervention to reduce over-dispensing and waste of asthma medications can succeed without compromising patient safety and can result in substantial cost savings. Medco Health Solutions, Inc.
'The Pill' May Reduce Asthma Symptoms (HealthDay)
Source: Y! Health Asthma News [2009.11.13]
HealthDay - FRIDAY, Nov. 13 (HealthDay News) -- Women with asthma may notice that
their asthma symptoms get worse at certain times of the month. Now, a new
study confirms that fluctuating female hormone levels appear to affect
airway inflammation, but oral contraceptives might help ease those
changes.
Published Studies Related to Alvesco (Ciclesonide Inhalation)
Efficacy and safety of ciclesonide hydrofluoroalkane nasal aerosol once daily for the treatment of seasonal allergic rhinitis. [2009.08]
BACKGROUND: Aerosol-based corticosteroid nasal formulations may be preferred over current aqueous nasal sprays by some patients because they traditionally cause less pharyngeal and anterior nose runoff. OBJECTIVE: To determine the optimal dose, safety, and tolerability of ciclesonide hydrofluoroalkane nasal aerosol in patients with seasonal allergic rhinitis (SAR)... CONCLUSIONS: Ciclesonide hydrofluoroalkane nasal aerosol demonstrated statistically significant improvements in SAR symptoms vs placebo. On the basis of comparable efficacy and safety profiles observed for all doses, these results suggest that the 75-microg and 150-microg doses of ciclesonide hydrofluoroalkane appear appropriate for further evaluation of efficacy.
Effects of ciclesonide and fluticasone on cortisol secretion in patients with persistent asthma. [2009.06]
We compared the systemic and clinical effects of ciclesonide (CIC) and fluticasone propionate (FP) administered, in addition to CIC 160 microg x day(-1) and salmeterol 50 microg twice daily, in 32 patients with persistent asthma using a randomised double-blind, placebo-controlled, double-dummy, five-period crossover design...
Efficacy and safety of ciclesonide once daily and fluticasone propionate twice daily in children with asthma. [2009.06]
BACKGROUND: Ciclesonide is a new inhaled corticosteroid (ICS). Information about its clinical efficacy and safety in relation to other ICS in children is needed for clinical positioning. OBJECTIVE: This 12-week, randomized, double-blind, double-dummy, three-arm, parallel-group study compared the efficacy and safety of ciclesonide with fluticasone propionate in children with mainly moderate and severe persistent asthma... CONCLUSION: Once-daily ciclesonide has a clinical effect similar to that of fluticasone propionate, but does not suppress cortisol excretion, in children with moderate and severe asthma.
Efficacy and safety evaluation of ciclesonide in subjects with mild-to-moderate asthma not currently using inhaled corticosteroids. [2009.05]
Inhaled corticosteroids (ICSs) are a first-line treatment for persistent asthma. This study was designed to compare the efficacy and safety of ciclesonide (CIC) in subjects with mild-to-moderate persistent asthma not using an ICS... improved disease control in subjects with mild-to-moderate persistent asthma not using an ICS and provided greater improvements than CIC160 q.d.
Efficacy and safety evaluation of ciclesonide in mild-to-moderate persistent asthma previously treated with inhaled corticosteroids. [2009.05]
Inhaled corticosteroids (ICSs) are recommended as first-line treatment for persistent asthma. This study was designed to evaluate the ability of ciclesonide (CIC) in subjects with stable asthma previously receiving another ICS or ICS/long-acting beta(2)-agonist (LABA) to maintain asthma disease control...
Clinical Trials Related to Alvesco (Ciclesonide Inhalation)
Ciclesonide for the Treatment of Airway Hyperresponsiveness (BY9010/CH-101) [Recruiting]
The study objective is to investigate in a placebo-controlled, double-blind manner the
effect of inhaled corticosteroid (ciclesonide) on airway hyperresponsiveness measured as
having PD15 mannitol. Treatment medication will be administered as follows: 320 microgram
ciclesonide or placebo will be inhaled once daily. The study duration consists of a
treatment period of 4 weeks. The study will provide further data on safety of ciclesonide.
A Pilot Investigation of Ciclesonide When Administered as a Hypotonic Versus an Isotonic Formulation of Ciclesonide Nasal Spray [Not yet recruiting]
Efficacy of Ciclesonide During the Cold Season in Patients Older Than 12 Years With Persistent Asthma [Recruiting]
The aim of the study is to evaluate the efficacy of ciclesonide in patients with persistent
asthma over 3 months, especially in the cold season. Ciclesonide will be inhaled by a
metered-dose inhaler. The study will provide further data on safety and tolerability of
ciclesonide.
Responsiveness of Lower Airways in Adult Patients (18-60 y) With Stable Asthma After Treatment With Ciclesonide and Fluticasone Propionate (BY9010/NL-101) [Recruiting]
The aim of this study is to compare the responsiveness of lower airways in adult patients
with stable asthma after treatment with ciclesonide and fluticasone propionate. Treatment
medication will be administered as follows: ciclesonide will be inhaled once daily at one
dose level, fluticasone propionate will be inhaled twice daily at one dose level. The study
duration consists of a baseline period (5 weeks) and a treatment period (5 weeks). The study
will provide further data on safety and tolerability of ciclesonide.
Efficacy of Ciclesonide Inhaled Once Daily Versus Other Corticosteroids Used for Treatment of Mild Asthma in Children (4 to 11 y) (BY9010/CA-101) [Recruiting]
The aim of this study is to compare the efficacy of ciclesonide with respect to reduction of
the number of asthma exacerbations in children with mild persistent asthma. Treatment
medication will be administered as follows: ciclesonide will be inhaled once daily, using one
of the two dose levels versus placebo together with other corticosteroids used as
intermittent treatment. The study duration consists of a baseline period (3 to 4 weeks) and a
treatment period (12 months). The study will provide further data on safety and tolerability
of ciclesonide.
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