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Aldoril (Methyldopa / Chlorothiazide) - Summary

 
 



WARNING

This fixed combination drug is not indicated for initial therapy of hypertension. Hypertension requires therapy titrated to the individual patient. If the fixed combination represents the dosage so determined, its use may be more convenient in patient management. The treatment of hypertension is not static, but must be re-evaluated as conditions in each patient warrant.

 

ALDORIL SUMMARY

TABLETS
ALDORIL ®
(METHYLDOPA-HYDROCHLOROTHIAZIDE)

ALDORIL (Methyldopa-Hydrochlorothiazide) combines two antihypertensives: methyldopa and hydrochlorothiazide.

ALDORIL is indicated for the treatment of hypertension.


See all Aldoril indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Aldoril (Methyldopa / Chlorothiazide)

Hypertension before the age of 55 increases risk of cardiovascular death
Source: Cardiovascular / Cardiology News From Medical News Today [2017.05.19]
When someone gets diagnosed with hypertension, either early (before the age of 55) or later in life, can have important health ramifications.

Options Emerging for Pulmonary Hypertension, Chronic Cough
Source: Medscape Allergy & Clinical Immunology Headlines [2017.05.15]
Results from the MERIT study evaluating macitentan in pulmonary hypertension will be presented at the American Thoracic Society Conference, along with a study of a P2X3 antagonist for chronic cough.
Medscape Medical News

Simple blood tests lead to improved hypertension treatment in African countries
Source: Hypertension News From Medical News Today [2017.05.04]
Using two simple blood tests, Western University researchers were able to drastically improve treatment for resistant hypertension across three sites in Nigeria, Kenya and South Africa.

Diabetes and hypertension: What is the relationship?
Source: Hypertension News From Medical News Today [2017.04.29]
Hypertension, or high blood pressure, is linked to diabetes, and each condition can make the other worse. How can people reduce the associated risks?

Endocrine Society issues statement to improve detection of curable forms of hypertension
Source: Endocrinology News From Medical News Today [2017.04.10]
A new Scientific Statement issued by the Endocrine Society advises healthcare providers on ways to spot hormonal causes of high blood pressure that can be cured with surgery or treated effectively...

more news >>

Published Studies Related to Aldoril (Methyldopa / Chlorothiazide)

Combination of a thiazide, a vasodilator and reserpine compared with methyldopa plus hydrochlorothiazide in the treatment of hypertension in Zimbabwe. [1990.03.03]
Brinerdin (Sandoz), a combination of a diuretic (clopamide 5 mg), a vasodilator (dihydro-ergocristine 0.5 mg) and reserpine (0.1 mg) (CDR) was compared with methyldopa (MD) plus hydrochlorothiazide (HCT) for antihypertensive effect, adverse reactions, compliance and patient preference in an open cross-over trial...

Evaluation of the efficacy and safety of enalapril plus hydrochlorothiazide plus methyldopa vs standard triple therapy in the treatment of moderate to severe hypertension: results from a multicentre study. [1990.02]
We report the results of a randomized, double-blind, parallel group multicentre study in 120 patients with moderate to severe hypertension, comparing two different types of antihypertensive treatment: a) the standard 'triple therapy' with hydrochlorothiazide, propranolol and hydralazine, and b) the combination of an ACE inhibitor, enalapril with hydrochlorothiazide (HCTZ) and methyldopa...

Oral enalapril-hydrochlorothiazide-methyldopa as first line treatment for severe hypertension in Nigerians. [2004.01]
A combination of low-dose oral enalapril, methyldopa and hydrochlorothiazide was evaluated in the acute treatment of severe hypertension. Blood pressure moved from an average 210/120 mmHg at the onset to an average 135/79 mmHg within 24 hours, without any significant side effects and at about half the cost of commonly used parenteral hydralazine..

more studies >>


Page last updated: 2017-05-19

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