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Aldoclor (Methyldopa / Chlorothiazide) - Summary



This fixed combination drug is not indicated for initial therapy of hypertension. Hypertension requires therapy titrated to the individual patient. If the fixed combination represents the dosage so determined, its use may be more convenient in patient management. The treatment of hypertension is not static, but must be re-evaluated as conditions in each patient warrant.



ALDOCLOR (Methyldopa-Chlorothiazide) combines two antihypertensives: methyldopa and chlorothiazide.

ALDOCLOR is indicated for the treatment of hypertension.

See all Aldoclor indications & dosage >>


Media Articles Related to Aldoclor (Methyldopa / Chlorothiazide)

New AHA Statement on Hypertension and Cognitive Function
Source: Medscape NeurologyHeadlines [2016.10.13]
A new statement from the American Heart Association recommends 'judicious' treatment of high blood pressure to protect against subsequent cognitive decline.
Medscape Medical News

AHA Statement: Hypertension, Dementia Linked (CME/CE)
Source: MedPage Today Nephrology [2016.10.12]
(MedPage Today) -- "Judicious" antihypertensive tx suggested despite limited evidence

Hypertension in children, teens linked to poorer cognitive skills
Source: Hypertension News From Medical News Today [2016.09.30]
Researchers found that children and adolescents with high blood pressure performed worse on cognitive tests than those with normal blood pressure.

Innovative sound therapy treats hypertension and migraine
Source: Headache / Migraine News From Medical News Today [2016.09.17]
A groundbreaking device that aligns the left and right brain using sound alone may reduce the symptoms of migraine, hypertension, and insomnia.

Hypertension: Releasing the pressure at its source
Source: Hypertension News From Medical News Today [2016.09.07]
Researchers eyeing first new anti-hypertensive drug treatment strategy in more than 15 years.

more news >>

Published Studies Related to Aldoclor (Methyldopa / Chlorothiazide)

Combination of a thiazide, a vasodilator and reserpine compared with methyldopa plus hydrochlorothiazide in the treatment of hypertension in Zimbabwe. [1990.03.03]
Brinerdin (Sandoz), a combination of a diuretic (clopamide 5 mg), a vasodilator (dihydro-ergocristine 0.5 mg) and reserpine (0.1 mg) (CDR) was compared with methyldopa (MD) plus hydrochlorothiazide (HCT) for antihypertensive effect, adverse reactions, compliance and patient preference in an open cross-over trial...

Evaluation of the efficacy and safety of enalapril plus hydrochlorothiazide plus methyldopa vs standard triple therapy in the treatment of moderate to severe hypertension: results from a multicentre study. [1990.02]
We report the results of a randomized, double-blind, parallel group multicentre study in 120 patients with moderate to severe hypertension, comparing two different types of antihypertensive treatment: a) the standard 'triple therapy' with hydrochlorothiazide, propranolol and hydralazine, and b) the combination of an ACE inhibitor, enalapril with hydrochlorothiazide (HCTZ) and methyldopa...

Oral enalapril-hydrochlorothiazide-methyldopa as first line treatment for severe hypertension in Nigerians. [2004.01]
A combination of low-dose oral enalapril, methyldopa and hydrochlorothiazide was evaluated in the acute treatment of severe hypertension. Blood pressure moved from an average 210/120 mmHg at the onset to an average 135/79 mmHg within 24 hours, without any significant side effects and at about half the cost of commonly used parenteral hydralazine..

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Page last updated: 2016-10-13

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