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Aldactone (Spironolactone) - Current Clinical Trials


Aldactone Related Clinical Trials

High-Dose Aldactone for Treatment of Diuretic Resistant Heart Failure [Recruiting]

Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure [Recruiting]

Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension [Recruiting]

Short Term Spironolactone for Prevention of Acute Kidney Injury After Cardiac Surgery [Recruiting]

The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study [Not yet recruiting]

Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and Cetuximab [Active, not recruiting]

Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease [Recruiting]

Interest of Topical Spironolactone's Administration to Prevent Corticoid-induced Epidermal Atrophy [Completed]

L-Arginine and Spironolactone Trial in Dialysis-Dependent ESRD [Withdrawn]

Spironolactone for Paroxysmal Atrial Fibrillation [Recruiting]

Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure [Recruiting]

Spironolactone Plus Metformin in Polycystic Ovary Syndrome [Completed]

Spironolactone Against Anthracycline-induced Cardiomyopathy [Completed]

The Effect of Spironolactone on Pain in Older People With Osteoarthritis [Recruiting]

Effects of Spironolactone in Dialysis [Recruiting]

Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure? [Completed]

Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis [Recruiting]

Effect of Spironolactone and Vitamin E in Patients With Nonalcoholic Fatty Liver Disease [Completed]

Efficacy of Spironolactone in Cameroonian Diabetic Patients With Resistant Hypertension [Completed]

Spironolactone and Prevention of Calcineurin Inhibitor Toxicity in Kidney Transplant Recipients [Suspended]

Mineralocorticoid Receptor Antagonist and Kidney Allograft Histology [Enrolling by invitation]

The Use of 5mg Finasteride Versus 200mg Spironolactone and Topical 5% Minoxidil in Treating Postmenopausal Female Androgenetic Alopecia [Not yet recruiting]

Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess [Not yet recruiting]

The Efficacy of Spironolactone in Patients With Resistant Hypertension [Terminated]

Hemodynamic Effects of Chronic Administration of Spironolactone and/or Propranolol in Alcoholic Cirrhotic Patients [Terminated]

Use of Spironolactone for the Prevention of Electrolyte Abnormalities in Patients Treated With Amphotericin B [Terminated]

Comparison of Effects of Eplerenone Versus Spironolactone in Heart Failure Patients With Glucose Intolerance or Type 2 Diabetes [Recruiting]

Addition of Spironolactone in Patients With Resistant Arterial Hypertension [Recruiting]

Spironolactone in Adult Congenital Heart Disease [Active, not recruiting]

Safety and Cardiovascular Efficacy of Spironolactone in Dialysis-Dependent ESRD Trial [Recruiting]

The Effects of Spironolactone on Calcineurin Inhibitor Induced Nephrotoxicity [Enrolling by invitation]

Spironolactone in Patients With Single Ventricle Heart [Completed]

Therapeutic Potential for Aldosterone Inhibition in Duchenne Muscular Dystrophy [Recruiting]

Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF) [Completed]

Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure [Completed]

Comparing the Effects of Spironolactone With Chlortalidone on LV Mass and Arterial Stiffness in Patients With CKD [Recruiting]

Spironolactone and Prevention of Peritoneal Fibrosis in Peritoneal Dialysis [Completed]

Hemodynamic Effects of Spironolactone in Patients With Heart Failure [Completed]

Safety of Hormonal Contraceptives Therapies in Polycystic Ovary Syndrome (PCOS) Women [Completed]

Effects of Spironolactone on Cardio- and Cerebrovascular Morbidity and Mortality in Hemodialysis Patients [Completed]

Novel Treatment for Diastolic Heart Failure in Women [Completed]

Spironolactone in Diabetic Nephropathy [Completed]

Clinical Trial Studying the Effects of Spironolactone on Heart and Skeletal Muscle Function in Chronic Alcoholics [Suspended]

The Effect of Spironolactone on Blood Pressure in Type-2 Diabetics With Resistant Hypertension [Completed]

Impacts of Aldosterone Blockade on Myocardial Remodeling in Hypertensive Patients With Diastolic Failing Heart [Completed]

Spironolactone for Reducing Proteinuria in Diabetic Nephropathy [Completed]

Spironolactone Safety in Dialysis Patients [Withdrawn]

Larger Dose of Spironolactone for the Treatment of Patients With Nonischemic Cardiomyopathy [Terminated]

Spironolactone to Decrease Potassium Wasting in Hypercalciurics on Thiazides Diuretics [Completed]

Aliskiren and Renin Inhibition in Diastolic Heart Failure [Withdrawn]

Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney [Completed]

Evaluation of CLP With and Without Spironolactone in Heart Failure Patients With Chronic Kidney Disease [Completed]

Efficacy of Therapy With the Spironolactone Pills Compared to Minoxidil Lotion in Female Pattern Hair Loss [Recruiting]

The Effects of Amiloride and Spironolactone on Renophysiological and Cardiovascular Variables [Completed]

ALdosterone Antagonist Chronic HEModialysis Interventional Survival Trial [Recruiting]

Mineralocorticoid Receptor Antagonists in End Stage Renal Disease [Recruiting]

Effect of Aldosterone on Energy Starvation in Heart Failure [Active, not recruiting]

Effects of Spironolactone Combination Therapy on Proteinuria, Kidney Function, and Blood Pressure [Completed]

Spironolactone for Pulmonary Arterial Hypertension [Recruiting]

Etiology of Sleep Apnea-related Hyperaldosteronism - BP Treatment [Completed]

Aldosterone Blockade Early After Acute Myocardial Infarction [Completed]

Evaluation of the Efficacy of Diuretics for Symptomatic Malignant Ascites Episodes in Advanced Stage of Cancer (DIASC) [Not yet recruiting]

Autoregulation of Glomerular Filtration Rate in Patients With Type 1 Diabetes During Spironolactone Therapy [Completed]

PIE II: Pharmacological Intervention in the Elderly II [Completed]

Proteomic Prediction and Renin Angiotensin Aldosterone System Inhibition Prevention Of Early Diabetic nephRopathy In TYpe 2 Diabetic Patients With Normoalbuminuria [Recruiting]

Residual Renal Function Preservation in Peritoneal Dialysis Patients [Recruiting]

Fracture Risk With Thiazolidinediones [Completed]

Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy [Recruiting]

Left Ventricular Hypertrophy and Spironolactone in End Stage Renal Disease [Completed]

Cardiovascular Protective Effect of Spironolactone in Hemodialysis [Recruiting]

Eplerenone Versus Spironolactone as Treatment of Ascites Due to Liver Cirrhosis; a Study of Efficacy and Side Effects [Recruiting]

RLY5016 in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN) [Completed]

Aldosterone and the Metabolic Syndrome [Recruiting]

Search of Biomarkers of Mineralocorticoid Receiver Activity : the Value of Neutrophil Gelatinase Associated Lipocalin (NGAL)in Serum or Urine in Human [Completed]

A Study To Evaluate The Safety And Tolerability Of PF-03882845 In Patients With Type 2 Diabetic Nephropathy [Terminated]

A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1) [Withdrawn]

Treatment of Boys With Precocious Puberty [Completed]

Resistant Hypertension Optimal Treatment [Recruiting]

A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II) [Recruiting]

Biomarker Guided Therapies in Stage A/B Heart Failure [Recruiting]

Optimalization of Nephroprotection Using Agents Inhibiting Renin-Angiotensin-Aldosterone System [Completed]

Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease [Recruiting]

Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome [Completed]

SCREEN-HFI (SCReening Evaluation of the Evolution of New Heart Failure Intervention Study) [Completed]

Spironolactone Versus Spironolactone Plus Furosemide (SVSSF) [Completed]

Mineralocorticoid Receptor and Obesity Induced Cardiovascular Complications [Completed]

BAY94-8862 Dose Finding Trial in Subjects With Chronic Heart Failure and Mild (Part A) or Moderate (Part B) Chronic Kidney Disease [Completed]

Changes in Endothelial Function and Biomarkers in African Americans (AA) With Metabolic Syndrome [Active, not recruiting]

Tissue Sodium in Pre-hypertensive Patients [Recruiting]

Effect of Aldosterone Blockade on Arterial Compliance [Completed]

Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF) [Completed]

Importance of Aldosterone in the Pathogenesis of Hypertensive Heart Disease [Completed]

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