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Albuterol HFA (Albuterol Sulfate) - Summary

 
 



ALBUTEROL HFA SUMMARY

Albuterol Sulfate HFA
INHALATION AEROSOL
For Oral Inhalation Only
PRESCRIBING INFORMATION

The active ingredient of Albuterol Sulfate HFA Inhalation Aerosol is albuterol sulfate, a racemic salt, which is a relatively selective beta2-adrenergic bronchodilator.

Albuterol Sulfate HFA Inhalation Aerosol is indicated in adults and children 12 years of age and older for the treatment or prevention of bronchospasm with reversible obstructive airway disease.


See all Albuterol HFA indications & dosage >>

NEWS HIGHLIGHTS

Published Studies Related to Albuterol HFA (Albuterol)

Active albuterol or placebo, sham acupuncture, or no intervention in asthma. [2011.07.14]
BACKGROUND: In prospective experimental studies in patients with asthma, it is difficult to determine whether responses to placebo differ from the natural course of physiological changes that occur without any intervention. We compared the effects of a bronchodilator, two placebo interventions, and no intervention on outcomes in patients with asthma... CONCLUSIONS: Although albuterol, but not the two placebo interventions, improved FEV(1) in these patients with asthma, albuterol provided no incremental benefit with respect to the self-reported outcomes. Placebo effects can be clinically meaningful and can rival the effects of active medication in patients with asthma. However, from a clinical-management and research-design perspective, patient self-reports can be unreliable. An assessment of untreated responses in asthma may be essential in evaluating patient-reported outcomes. (Funded by the National Center for Complementary and Alternative Medicine.).

Comparative efficacy of inhaled albuterol between two hand-held delivery devices in horses with recurrent airway obstruction. [2011.07]
REASONS FOR PERFORMING STUDY: Studies investigating the clinical efficacy of albuterol administered with the same propellant and commercially available delivery devices in horses with recurrent airway obstruction (RAO) are not currently available. OBJECTIVES: To determine the efficacy of aerosolised albuterol administered to horses with RAO by means of 2 commercially available, hand-held delivery devices... CONCLUSIONS: Aerosolised albuterol is an effective bronchodilator in horses with recurrent airway obstruction. There is no statistically significant difference between the 2 commercially available aerosol delivery devices in terms of efficacy. POTENTIAL RELEVANCE: Aerosolised albuterol is effectively delivered using currently available devices leading to maximal bronchodilation in horses with RAO at an average dose of 540 microg. (c) 2011 EVJ Ltd.

Efficacy of racemic albuterol versus levalbuterol used as a continuous nebulization for the treatment of acute asthma exacerbations: a randomized, double-blind, clinical trial. [2011.03]
OBJECTIVE: To compare racemic albuterol (RAC) with levalbuterol (LEV) in continuous form for the treatment of acute pediatric asthma exacerbations in the emergency department... CONCLUSIONS: At the doses used, RAC appears to be superior to LEV with respect to changes in FEV1 and asthma score. There was no significant difference between the drugs with respect to admission rates or side-effect profile.

Active albuterol or placebo, sham acupuncture, or no intervention in asthma. [2011]
on outcomes in patients with asthma... CONCLUSIONS: Although albuterol, but not the two placebo interventions, improved

Efficacy of racemic albuterol versus levalbuterol used as a continuous nebulization for the treatment of acute asthma exacerbations: a randomized, double-blind, clinical trial. [2011]
emergency department... CONCLUSIONS: At the doses used, RAC appears to be superior to LEV with respect to

more studies >>

Clinical Trials Related to Albuterol HFA (Albuterol)

Testing Potential Synergistic Effects of Albuterol and Caffeine on Metabolic Rate [Completed]

Preterm Infant Inhaled Albuterol Dosing [Recruiting]
The purpose of this study is to help determine the best dose of albuterol in premature babies at risk of developing bronchopulmonary dysplasia (BPD). BPD is the chronic lung disease of prematurity and is associated with increased morbidity and mortality, longer hospital stays, and increased healthcare utilization. Albuterol is an inhaled medication frequently used in premature infants with chronic lung disease and in people with asthma. It is believed to be safe, but the optimal dose for infants is not clear. The investigators hypothesize that albuterol may help a subset of premature infants with lung disease, but they need to determine the best dose prior to doing research about how effective it is for chronic lung disease/BPD. Response to each of three doses of albuterol will be measure using pulmonary function tests.

Efficacy and Safety Comparison of Albuterol Spiromax® and ProAir® Hydrofluoroalkane (HFA) in Pediatric Patients [Completed]
This is a multicenter, randomized, double-blind, double-dummy, placebo-controlled, single-dose, 5-treatment, 5-period, 5-way crossover study in pediatric patients with persistent asthma. The primary purpose of this study is to compare the efficacy and safety of Albuterol Spiromax with that of ProAir HFA in pediatric asthma patients at 2 delivered dose levels equivalent to 90 mcg and 180 mcg of albuterol base.

Single-Dose Cross-Over Study of the Effects of Albuterol-HFA in Exercise Induced Bronchoconstriction [Terminated]
This clinical study will evaluate and establish the protective effects of Amphastar's Albuterol Sulfate HFA Inhalation Aerosol (Albuterol-HFA), in preventing exercise-induced bronchoconstriction (EIB) in adolescent and adult asthmatic patients, in comparison with (1) Proventil®-HFA (Reference drug and Active Control ), and (2) Placebo-HFA control (HFA propellant only). Safety of the test drug, Albuterol-HFA, will also be evaluated in comparison to the Active and Placebo Controls. Analyses will be performed to determine if the Armstrong's Albuterol-HFA has resulted in a significant bronchoprotective effect, with attenuated Max % Fall in FEV1, in comparison to the Placebo-HFA control.

Efficacy of Inhaled Albuterol Spiromax® in Subjects With Persistent Asthma With Steady State Pharmacokinetics [Completed]
The primary objective of this study is to evaluate the efficacy of Albuterol Spiromax® versus placebo in subjects with persistent asthma.

more trials >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 5 ratings/reviews, Albuterol HFA has an overall score of 10. The effectiveness score is 10 and the side effect score is 10. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
 

Albuterol HFA review by 47 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   copd
Dosage & duration:   17grams (dosage frequency: every 2 to 4 hours) for the period of till they took it off market
Other conditions:   none
Other drugs taken:   advair
  
Reported Results
Benefits:   copd
Side effects:   this was given to me for copd and chronic bronchitus there were no side effects
Comments:   i used the albuterol in haler as a life saver every 2 to 4 hours. i use the adair 250/50 i think twice a day. these medications help me breathe. since they have discontinued the albuterol i have been using a product call proventic. because of the global warning they have taken somethinng out of these products that help it push into lungs, they say the other is the sme does and it may be but it doesn't seem to work as well and i have to use more of it.

 

Albuterol HFA review by 47 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   copd
Dosage & duration:   17grams (dosage frequency: every 2 to 4 hours) for the period of till they took it off market
Other conditions:   none
Other drugs taken:   advair
  
Reported Results
Benefits:   copd
Side effects:   this was given to me for copd and chronic bronchitus there were no side effects
Comments:   i used the albuterol in haler as a life saver every 2 to 4 hours. i use the adair 250/50 i think twice a day. these medications help me breathe. since they have discontinued the albuterol i have been using a product call proventic. because of the global warning they have taken somethinng out of these products that help it push into lungs, they say the other is the sme does and it may be but it doesn't seem to work as well and i have to use more of it.

 

Albuterol HFA review by 47 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   copd
Dosage & duration:   17grams (dosage frequency: every 2 to 4 hours) for the period of till they took it off market
Other conditions:   none
Other drugs taken:   advair
  
Reported Results
Benefits:   copd
Side effects:   this was given to me for copd and chronic bronchitus there were no side effects
Comments:   i used the albuterol in haler as a life saver every 2 to 4 hours. i use the adair 250/50 i think twice a day. these medications help me breathe. since they have discontinued the albuterol i have been using a product call proventic. because of the global warning they have taken somethinng out of these products that help it push into lungs, they say the other is the sme does and it may be but it doesn't seem to work as well and i have to use more of it.

See all Albuterol HFA reviews / ratings >>

Page last updated: 2013-02-10

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