Albuterol HFA (Albuterol Sulfate) - Summary

ALBUTEROL HFA SUMMARY

Albuterol Sulfate HFA
INHALATION AEROSOL
For Oral Inhalation Only
PRESCRIBING INFORMATION

The active ingredient of Albuterol Sulfate HFA Inhalation Aerosol is albuterol sulfate, a racemic salt, which is a relatively selective beta₂-adrenergic bronchodilator.

Albuterol Sulfate HFA Inhalation Aerosol is indicated in adults and children 12 years of age and older for the treatment or prevention of bronchospasm with reversible obstructive airway disease.

See all Albuterol HFA indications & dosage >>

NEWS HIGHLIGHTS

Published Studies Related to Albuterol HFA (Albuterol)

Active albuterol or placebo, sham acupuncture, or no intervention in asthma. [2011.07.14]
BACKGROUND: In prospective experimental studies in patients with asthma, it is difficult to determine whether responses to placebo differ from the natural course of physiological changes that occur without any intervention. We compared the effects of a bronchodilator, two placebo interventions, and no intervention on outcomes in patients with asthma... CONCLUSIONS: Although albuterol, but not the two placebo interventions, improved FEV(1) in these patients with asthma, albuterol provided no incremental benefit with respect to the self-reported outcomes. Placebo effects can be clinically meaningful and can rival the effects of active medication in patients with asthma. However, from a clinical-management and research-design perspective, patient self-reports can be unreliable. An assessment of untreated responses in asthma may be essential in evaluating patient-reported outcomes. (Funded by the National Center for Complementary and Alternative Medicine.).

Comparative efficacy of inhaled albuterol between two hand-held delivery devices in horses with recurrent airway obstruction. [2011.07]
REASONS FOR PERFORMING STUDY: Studies investigating the clinical efficacy of albuterol administered with the same propellant and commercially available delivery devices in horses with recurrent airway obstruction (RAO) are not currently available. OBJECTIVES: To determine the efficacy of aerosolised albuterol administered to horses with RAO by means of 2 commercially available, hand-held delivery devices... CONCLUSIONS: Aerosolised albuterol is an effective bronchodilator in horses with recurrent airway obstruction. There is no statistically significant difference between the 2 commercially available aerosol delivery devices in terms of efficacy. POTENTIAL RELEVANCE: Aerosolised albuterol is effectively delivered using currently available devices leading to maximal bronchodilation in horses with RAO at an average dose of 540 microg. (c) 2011 EVJ Ltd.

Efficacy of racemic albuterol versus levalbuterol used as a continuous nebulization for the treatment of acute asthma exacerbations: a randomized, double-blind, clinical trial. [2011.03]
OBJECTIVE: To compare racemic albuterol (RAC) with levalbuterol (LEV) in continuous form for the treatment of acute pediatric asthma exacerbations in the emergency department... CONCLUSIONS: At the doses used, RAC appears to be superior to LEV with respect to changes in FEV1 and asthma score. There was no significant difference between the drugs with respect to admission rates or side-effect profile.

Active albuterol or placebo, sham acupuncture, or no intervention in asthma. [2011]
on outcomes in patients with asthma... CONCLUSIONS: Although albuterol, but not the two placebo interventions, improved

Efficacy of racemic albuterol versus levalbuterol used as a continuous nebulization for the treatment of acute asthma exacerbations: a randomized, double-blind, clinical trial. [2011]
emergency department... CONCLUSIONS: At the doses used, RAC appears to be superior to LEV with respect to

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Clinical Trials Related to Albuterol HFA (Albuterol)

Safety and Tolerability Study of Levalbuterol HFA and Racemic Albuterol HFA in Pediatrics Subjects With Asthma [Completed]
The purpose of this study is to compare the safety and tolerability of levalbuterol HFA metered dose inhaler (MDI) versus racemic albuterol HFA MDI in pediatric subjects 4-11 years of age with asthma

Chronic-Dose Safety and Efficacy Study of Albuterol-HFA-MDI In Pediatric Asthmatics [Active, not recruiting]

Controlled, 12-Week Study of Albuterol HFA Versus the Active Control, Proventil(R)-HFA in Asthmatic Patients [Active, not recruiting]
This 12-week clinical study evaluates the safety and efficacy of Albuterol Sulfate HFA Inhalation Aerosol (Albuterol-HFA, or: A004), Armstrong's proposed HFA formulation of metered dose inhaler (MDI) of Albuterol (Treatment T), in comparison with:

1. Placebo control: (HFA propellant only, Treatment P); and

2. Active control: 3M/Key's Proventil-HFA (Treatment R).

The treatments will be given as self-administered oral inhalations in adult and adolescent patients with mild-to-moderate asthma, for 12-weeks. Dosing regimen throughout the 12-week study is two actuations four times daily (QID).

Safety and Tolerability Study of Levalbuterol HFA Compared to Racemic Albuterol HFA in Subjects With Asthma [Completed]

Study of Levalbuterol and Racemic Albuterol in Pediatric Subjects With Reactive Airways Disease (RAD) [Completed]
The purpose of this study is to compare the efficacy of two dose levels of levalbuterol compared with one dose level of racemic albuterol in pediatric subjects aged birth to 48 months old.

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PATIENT REVIEWS / RATINGS / COMMENTS

Albuterol HFA review by 47 year old female patient
		Rating
Overall rating:
Effectiveness:		Highly Effective
Side effects:		No Side Effects
		Treatment Info
Condition / reason:		copd
Dosage & duration:		17grams (dosage frequency: every 2 to 4 hours) for the period of till they took it off market
Other conditions:		none
Other drugs taken:		advair
		Reported Results
Benefits:		copd
Side effects:		this was given to me for copd and chronic bronchitus there were no side effects
Comments:		i used the albuterol in haler as a life saver every 2 to 4 hours. i use the adair 250/50 i think twice a day. these medications help me breathe. since they have discontinued the albuterol i have been using a product call proventic. because of the global warning they have taken somethinng out of these products that help it push into lungs, they say the other is the sme does and it may be but it doesn't seem to work as well and i have to use more of it.

Albuterol HFA review by 47 year old female patient
		Rating
Overall rating:
Effectiveness:		Highly Effective
Side effects:		No Side Effects
		Treatment Info
Condition / reason:		copd
Dosage & duration:		17grams (dosage frequency: every 2 to 4 hours) for the period of till they took it off market
Other conditions:		none
Other drugs taken:		advair
		Reported Results
Benefits:		copd
Side effects:		this was given to me for copd and chronic bronchitus there were no side effects
Comments:		i used the albuterol in haler as a life saver every 2 to 4 hours. i use the adair 250/50 i think twice a day. these medications help me breathe. since they have discontinued the albuterol i have been using a product call proventic. because of the global warning they have taken somethinng out of these products that help it push into lungs, they say the other is the sme does and it may be but it doesn't seem to work as well and i have to use more of it.

Albuterol HFA review by 47 year old female patient
		Rating
Overall rating:
Effectiveness:		Highly Effective
Side effects:		No Side Effects
		Treatment Info
Condition / reason:		copd
Dosage & duration:		17grams (dosage frequency: every 2 to 4 hours) for the period of till they took it off market
Other conditions:		none
Other drugs taken:		advair
		Reported Results
Benefits:		copd
Side effects:		this was given to me for copd and chronic bronchitus there were no side effects
Comments:		i used the albuterol in haler as a life saver every 2 to 4 hours. i use the adair 250/50 i think twice a day. these medications help me breathe. since they have discontinued the albuterol i have been using a product call proventic. because of the global warning they have taken somethinng out of these products that help it push into lungs, they say the other is the sme does and it may be but it doesn't seem to work as well and i have to use more of it.