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Albuterol HFA (Albuterol Sulfate) - Summary

 


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ALBUTEROL HFA SUMMARY

Albuterol Sulfate HFA
INHALATION AEROSOL
For Oral Inhalation Only
PRESCRIBING INFORMATION

The active ingredient of Albuterol Sulfate HFA Inhalation Aerosol is albuterol sulfate, a racemic salt, which is a relatively selective beta2-adrenergic bronchodilator.

Albuterol Sulfate HFA Inhalation Aerosol is indicated in adults and children 12 years of age and older for the treatment or prevention of bronchospasm with reversible obstructive airway disease.


See all Albuterol HFA indications & dosage >>

ALBUTEROL HFA NEWS HIGHLIGHTS

Published Studies Related to Albuterol HFA (Albuterol)

The effects of nebulized albuterol on esophageal function in asthmatic patients. [2008.10]
CONCLUSIONS: Nebulized albuterol induces a dose-dependent reduction in LES basal pressure in asthmatic patients. These effects raise the possibility that gastroesophageal reflux may occur after bronchodilator therapy.

Effects of time, albuterol, and budesonide on the shape of the flow-volume loop in children with asthma. [2008.10]
BACKGROUND: Assessment of asthma through spirometric analysis in children is challenging because of often normal FEV(1) values. OBJECTIVE: We used Mead's slope ratio (SR; (dV /dV)/(V /V)) to analyze the shape of the flow-volume loop... CONCLUSION: Budesonide-treated patients have less concave flow-volume loops when compared with placebo-treated patients. Time and bronchodilator also make the flow-volume loop less concave. Furthermore, it appears that there are discrete bronchodilator- and corticosteroid-responsive components of airflow obstruction in pediatric asthma.

A cumulative dose study of levalbuterol and racemic albuterol administered by hydrofluoroalkane-134a metered-dose inhaler in asthmatic subjects. [2008.09]
BACKGROUND: The short-acting beta(2)-agonists levalbuterol and racemic albuterol are available for administration through a hydrofluoroalkane-134a (HFA) metered-dose inhaler (MDI). OBJECTIVE: This study compared the short-term safety and efficacy of cumulative doses of levalbuterol HFA MDI and racemic albuterol HFA MDI in asthmatic subjects... CONCLUSION: In this study single-day cumulative dosing of asthmatic subjects with levalbuterol HFA MDI or racemic albuterol HFA MDI resulted in similar improvements in FEV(1) and tolerability. Plasma (R)-albuterol levels and mean heart rate were less with levalbuterol HFA MDI.

Bronchodilator efficacy of the fixed combination of ipratropium and albuterol compared to albuterol alone in moderate-to-severe persistent asthma. [2008.08]
BACKGROUND: The potential of anticholinergics to provide bronchodilatory benefits over short-acting beta(2)-agonists (SABA) alone in patients with moderate-to-severe persistent asthma has not been well defined... CONCLUSION: IB+ALB resulted in significantly greater improvement in FEV(1) and longer duration of response compared to ALB alone in patients with moderate-to-severe persistent asthma (Trial number: 1012.50; ClinicalTrial.gov NCT00096616).

Temporal strength changes from resistance exercise and albuterol on unloaded muscle. [2008.07]
To assess unloaded knee extensor temporal strength changes, healthy subjects without asthma performed 40 continuous days of unilateral limb suspension, whereby their left leg refrained from normal weight-bearing and ambulatory activity. During the 40-day period, subjects performed resistance exercise (REX) with their unloaded leg on an inertial resistance ergometer and, as part of a double-blind design, consumed the maximal oral therapeutic dosage of albuterol (i.e., 16 mg.d) or a placebo (i.e., lactose) with no crossover...

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Clinical Trials Related to Albuterol HFA (Albuterol)

Safety and Tolerability Study of Levalbuterol HFA and Racemic Albuterol HFA in Pediatrics Subjects With Asthma [Completed]
The purpose of this study is to compare the safety and tolerability of levalbuterol HFA metered dose inhaler (MDI) versus racemic albuterol HFA MDI in pediatric subjects 4-11 years of age with asthma

Chronic-Dose Safety and Efficacy Study of Albuterol-HFA-MDI In Pediatric Asthmatics [Active, not recruiting]

Controlled, 12-Week Study of Albuterol HFA Versus the Active Control, Proventil(R)-HFA in Asthmatic Patients [Active, not recruiting]
This 12-week clinical study evaluates the safety and efficacy of Albuterol Sulfate HFA Inhalation Aerosol (Albuterol-HFA, or: A004), Armstrong's proposed HFA formulation of metered dose inhaler (MDI) of Albuterol (Treatment T), in comparison with:

1. Placebo control: (HFA propellant only, Treatment P); and

2. Active control: 3M/Key's Proventil-HFA (Treatment R).

The treatments will be given as self-administered oral inhalations in adult and adolescent patients with mild-to-moderate asthma, for 12-weeks. Dosing regimen throughout the 12-week study is two actuations four times daily (QID).

Safety and Tolerability Study of Levalbuterol HFA Compared to Racemic Albuterol HFA in Subjects With Asthma [Completed]

Study of Levalbuterol and Racemic Albuterol in Pediatric Subjects With Reactive Airways Disease (RAD) [Completed]
The purpose of this study is to compare the efficacy of two dose levels of levalbuterol compared with one dose level of racemic albuterol in pediatric subjects aged birth to 48 months old.

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ALBUTEROL HFA PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 1 ratings/reviews, Albuterol HFA has an overall score of 10. The effectiveness score is 10 and the side effect score is 10. The scores are on ten point scale: 10 - best, 1 - worst.
 

Albuterol HFA review by 47 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   copd
Dosage & duration:   17grams (dosage frequency: every 2 to 4 hours) for the period of till they took it off market
Other conditions:   none
Other drugs taken:   advair
  
Reported Results
Benefits:   copd
Side effects:   this was given to me for copd and chronic bronchitus there were no side effects
Comments:   i used the albuterol in haler as a life saver every 2 to 4 hours. i use the adair 250/50 i think twice a day. these medications help me breathe. since they have discontinued the albuterol i have been using a product call proventic. because of the global warning they have taken somethinng out of these products that help it push into lungs, they say the other is the sme does and it may be but it doesn't seem to work as well and i have to use more of it.

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Page last updated: 2009-02-07

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