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Akineton (Biperiden Hydrochloride) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

Atropine-like side effects such as dry mouth; blurred vision; drowsiness; euphoria or disorientation; urinary retention; postural hypotension; constipation; agitation; disturbed behavior may been seen. A case of generalized choreic movements has been reported in a Parkinson's disease patient when biperiden was added to carbidopa/levodopa. A reduction in rapid eye movement (REM) sleep, characterized by increased REM latency and decreased percentage of REM sleep, has been reported. There usually are no significant changes in blood pressure or heart rate in patients who have been given the parenteral form of AKINETON. Mild transient postural hypotension and bradycardia may occur. These side effects can be minimized or avoided by slow intravenous administration. No local tissue reactions have been reported following intramuscular injection. If gastric irritation occurs following oral administration, it can be avoided by administering the drug during or after meals.

The central anticholinergic syndrome can occur as an adverse reaction to properly prescribed anticholinergic medication. See OVERDOSAGE section for signs and symptoms of the central anticholinergic syndrome, and for treatment.



REPORTS OF SUSPECTED AKINETON SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Akineton. The information is not vetted and should not be considered as verified clinical evidence.

Possible Akineton side effects / adverse reactions in 45 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-02

Patient: 45 year old male weighing 86.0 kg (189.2 pounds)

Reactions: Pneumonia, Ileus, Respiratory Failure, Neuroleptic Malignant Syndrome

Adverse event resulted in: death

Suspect drug(s):
Cremin
    Dosage: granules
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 1996-10-01
    End date: 2011-07-19

Promethazine HCL
    Administration route: Oral
    Indication: Parkinsonism
    Start date: 1996-10-01
    End date: 2011-07-19

Fludecasin
    Indication: Schizophrenia
    Start date: 2004-05-25
    End date: 2011-06-20

Symmetrel
    Dosage: granules
    Administration route: Oral
    Indication: Parkinsonism
    Start date: 1996-10-01
    End date: 2011-07-19

Abilify
    Dosage: 3mg:05jul-07jul11, 6mg:08jul-11jul11, 9mg:12jul-19jul11.
    Administration route: Oral
    Indication: Schizophrenia
    Start date: 2011-07-05
    End date: 2011-07-19

Akineton
    Administration route: Oral
    Indication: Parkinsonism
    Start date: 1996-10-01
    End date: 2011-07-19

Pentona
    Administration route: Oral
    Indication: Parkinsonism
    Start date: 1996-10-01
    End date: 2011-07-19

Other drugs received by patient: Diazepam



Possible Akineton side effects / adverse reactions in 74 year old female

Reported by a pharmacist from France on 2011-10-04

Patient: 74 year old female

Reactions: Thrombocytopenia

Suspect drug(s):
Depakene
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-04-21
    End date: 2009-07-08

Risperdal
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-04-23

Risperdal
    Administration route: Oral

Risperdal
    Administration route: Oral
    End date: 2009-06-26

Akineton
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-04-21
    End date: 2009-06-26

Urbanyl
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-04-29
    End date: 2009-06-23

Zolpidem
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-04-21
    End date: 2009-07-13

Tiapride Panpharma
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-06-08
    End date: 2009-06-23



Possible Akineton side effects / adverse reactions in 51 year old female

Reported by a health professional (non-physician/pharmacist) from Italy on 2011-10-10

Patient: 51 year old female

Reactions: Agitation, Multiple Drug Overdose Intentional, Self Injurious Behaviour, Sopor

Suspect drug(s):
Akineton
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-01
    End date: 2011-10-01

Haldol
    Dosage: 0.2%
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-01
    End date: 2011-10-01

Lorazepam
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-10-01
    End date: 2011-10-01



See index of all Akineton side effect reports >>

Drug label data at the top of this Page last updated: 2006-06-13

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