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Adenosine (Adenosine) - Drug Interactions, Contraindications, Overdosage, etc

 
 



DRUG INTERACTIONS

ADENOSINE drug label information in our database does not contain a dedicated section on drug interactions. Please check subsections of WARNINGS AND PRECAUTIONS as well as other sources.

OVERDOSAGE

The half-life of adenosine injection is less than 10 seconds. Thus, adverse effects are generally rapidly self-limiting. Treatment of any prolonged adverse effects should be individualized and be directed toward the specific effect. Methylxanthines, such as caffeine and theophylline, are competitive antagonists of adenosine.

 

CONTRAINDICATIONS

Adenosine injection is contraindicated in:

  1. Second- or third-degree A-V block (except in patients with a functioning artificial pacemaker).
  2. Sinus node disease, such as sick sinus syndrome or symptomatic bradycardia (except in patients with a functioning artificial pacemaker).
  3. Known hypersensitivity to adenosine.

REFERENCES

  1. Paul T, Pfammatter. J-P. Adenosine: an effective and safe antiarrhythmic drug in pediatrics. Pediatrics Cardiology 1997; 18:118-126.

AKORN
Manufactured by: Akorn, Inc.
Lake Forest, IL 60045

AI00N
Rev. 10/13

 

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