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Adenosine (Adenosine) - Published Studies


Adenosine Related Published Studies

Well-designed clinical trials related to Adenosine

The effect of PDRN, an adenosine receptor A2A agonist, on the healing of chronic diabetic foot ulcers: results of a clinical trial. [2014]

Efficacy and safety of a novel dual modulator of adenosine triphosphate-citrate lyase and adenosine monophosphate-activated protein kinase in patients with hypercholesterolemia: results of a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial. [2013]

The new oral adenosine A1 receptor agonist capadenoson in male patients with stable angina. [2012]

Treatment of Unexplained Syncope: A Multicenter, Randomized Trial of Cardiac Pacing Guided by Adenosine 5'-triphosphate Testing. [2011.11.15]

Adenosine A2(A) receptor gene polymorphism (1976C>T) affects coronary flow reserve response during vasodilator stress testing in patients with non ischemic-dilated cardiomyopathy. [2011.08]

Role of adenosine in the control of choroidal blood flow during changes in ocular perfusion pressure. [2011.07.29]

Rationale, design, and results from RENO-DEFEND 1: a randomized, dose-finding study of the selective A1 adenosine antagonist SLV320 in patients hospitalized with acute heart failure. [2011.06]

The relative efficacy of adenosine versus verapamil for the treatment of stable paroxysmal supraventricular tachycardia in adults: a meta-analysis. [2011.06]

Effects of BG9928, an adenosine A receptor antagonist, in patients with congestive heart failure. [2011.06]

Effects of the adenosine A1 receptor antagonist rolofylline on renal function in patients with acute heart failure and renal dysfunction: results from PROTECT (Placebo-Controlled Randomized Study of the Selective Adenosine A1 Receptor Antagonist Rolofylline for Patients Hospitalized with Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function). [2011.05.10]

Reflex systemic sympatho-neural response to brachial adenosine infusion in treated heart failure. [2011.05]

The myocardial protective effects of adenosine pretreatment in children undergoing cardiac surgery: a randomized controlled clinical trial. [2011.05]

New method of intracoronary adenosine injection to prevent microvascular reperfusion injury in patients with acute myocardial infarction undergoing percutaneous coronary intervention. [2011.04.15]

Modulatory action of alpha-tocopherol on erythrocyte membrane adenosine triphosphatase against radiation damage in oral cancer. [2011.03]

Effect of myocardial protection of intracoronary adenosine and nicorandil injection in patients undergoing non-urgent percutaneous coronary intervention: A randomized controlled trial. [2011.01.20]

Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury. [2011]

High-dose intracoronary adenosine for myocardial salvage in patients with acute ST-segment elevation myocardial infarction. [2011]

Quantification of indirect pathway inhibition by the adenosine A2a antagonist SYN115 in Parkinson disease. [2010.12.01]

Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure. [2010.10.07]

Randomized clinical trial on the effects of adenosine 5'-triphosphate infusions on quality of life, functional status, and fatigue in preterminal cancer patients. [2010.10]

Adenosine receptor inhibition with theophylline attenuates the skin blood flow response to local heating in humans. [2010.09]

Airway hyperresponsiveness to methacholine, adenosine 5-monophosphate, mannitol, eucapnic voluntary hyperpnoea and field exercise challenge in elite cross-country skiers. [2010.09]

Attenuation of adenosine-induced myocardial perfusion heterogeneity by atenolol and other cardioselective beta-adrenoceptor blockers: a crossover myocardial perfusion imaging study. [2010.07]

Design and rationale of the PROTECT study: a placebo-controlled randomized study of the selective A1 adenosine receptor antagonist rolofylline for patients hospitalized with acute decompensated heart failure and volume overload to assess treatment effect on congestion and renal function. [2010.01]

Quantification of indirect pathway inhibition by the adenosine A2a antagonist SYN115 in Parkinson disease. [2010]

Improving the quality of infant sleep through the inclusion at supper of cereals enriched with tryptophan, adenosine-5'-phosphate, and uridine-5'-phosphate. [2009.12]

The myocardial protective effect of adenosine as an adjunct to intermittent blood cardioplegia during open heart surgery. [2009.12]

The ischemic preconditioning effect of adenosine in patients with ischemic heart disease. [2009.11.05]

Safety of binodenoson, a selective adenosine A2A receptor agonist vasodilator pharmacological stress agent, in healthy subjects with mild intermittent asthma. [2009.11]

Cardio-renal effects of the A1 adenosine receptor antagonist SLV320 in patients with heart failure. [2009.11]

Comparison of methacholine and adenosine inhalation challenge in patients with suspected asthma. [2009.10]

Electrophysiologic characteristics of wide QRS complexes during pharmacologic termination of sustained supraventricular tachycardias with verapamil and adenosine: observations from electrophysiologic study. [2009.10]

Adenosine receptor antagonist and augmented vasodilation during hypoxic exercise. [2009.10]

Intravenous administration of adenosine triphosphate disodium during primary percutaneous coronary intervention attenuates the transient rapid improvement of myocardial wall motion, not myocardial stunning, shortly after recanalization in acute anterior myocardial infarction. [2009.10]

Adenosine infusion attenuates soluble RAGE in endotoxin-induced inflammation in human volunteers. [2009.09]

Randomized trial of daily versus weekly administration of 2-chlorodeoxyadenosine in patients with hairy cell leukemia: a multicenter phase III trial (SAKK 32/98). [2009.09]

Preconditioning effects of adenosine in patients with severe coronary artery disease but preserved coronary flow reserve. [2009.08]

Effect of adenosine 5'-triphosphate infusions on the nutritional status and survival of preterminal cancer patients. [2009.08]

Adenosine modulates oesophageal sensorimotor function in humans. [2009.08]

Effect of high-dose intracoronary adenosine administration during primary percutaneous coronary intervention in acute myocardial infarction: a randomized controlled trial. [2009.08]

Regadenoson induces comparable left ventricular perfusion defects as adenosine: a quantitative analysis from the ADVANCE MPI 2 trial. [2009.08]

Randomized evaluation of intracoronary nitroprusside vs. adenosine after thrombus aspiration during primary percutaneous coronary intervention for the prevention of no-reflow in acute myocardial infarction: the REOPEN-AMI study protocol. [2009.07]

Application of a shortened inhaled adenosine-5'-monophosphate challenge in young children using the forced oscillation technique. [2009.07]

Rosuvastatin increases extracellular adenosine formation in humans in vivo: a new perspective on cardiovascular protection. [2009.06]

Maximal response plateau to adenosine 5'-monophosphate in asthma. Relationship with the response to methacholine, exhaled nitric oxide, and exhaled breath condensate pH. [2009.06]

Slow infusion of calcium channel blockers compared with intravenous adenosine in the emergency treatment of supraventricular tachycardia. [2009.05]

Head to head comparisons of two modalities of perfusion adenosine stress echocardiography with simultaneous SPECT. [2009.04.20]

Plaque retention by self-ligating vs elastomeric orthodontic brackets: quantitative comparison of oral bacteria and detection with adenosine triphosphate-driven bioluminescence. [2009.04]

Differences in heart rate response to adenosine and regadenoson in patients with and without diabetes mellitus. [2009.04]

Effect of levocetirizine on nasal provocation testing with adenosine monophosphate compared with allergen challenge in allergic rhinitis. [2009.03]

No effect of nutritional adenosine receptor antagonists on exercise performance in the heat. [2009.02]

First-pass dynamic contrast-enhanced MRI with extravasating contrast reagent: evidence for human myocardial capillary recruitment in adenosine-induced hyperemia. [2009.02]

The RegEx trial: a randomized, double-blind, placebo- and active-controlled pilot study combining regadenoson, a selective A(2A) adenosine agonist, with low-level exercise, in patients undergoing myocardial perfusion imaging. [2009.01]

Effects of intravenous adenosine 5'-triphosphate on intraoperative hemodynamics and postoperative pain in patients undergoing major orofacial surgery: a double-blind placebo-controlled study. [2009]

The myocardial protective effects of a moderate-potassium adenosine-lidocaine cardioplegia in pediatric cardiac surgery. [2008.12]

Phase 2, double-blind, placebo-controlled, dose-response trial of intravenous adenosine for perioperative analgesia. [2008.12]

Adenosine increases anagen hair growth and thick hairs in Japanese women with female pattern hair loss: a pilot, double-blind, randomized, placebo-controlled trial. [2008.12]

The PROTECT pilot study: a randomized, placebo-controlled, dose-finding study of the adenosine A1 receptor antagonist rolofylline in patients with acute heart failure and renal impairment. [2008.10]

Positron emission tomography analysis of [11C]KW-6002 binding to human and rat adenosine A2A receptors in the brain. [2008.09]

The reproducibility of adenosine monophosphate bronchial challenges in mild, steroid-naive asthmatics. [2008.08]

Safety of regadenoson, an adenosine A2A receptor agonist for myocardial perfusion imaging, in mild asthma and moderate asthma patients: a randomized, double-blind, placebo-controlled trial. [2008.05]

Safety of regadenoson, a selective adenosine A2A agonist, in patients with chronic obstructive pulmonary disease: A randomized, double-blind, placebo-controlled trial (RegCOPD trial). [2008.05]

Methacholine vs adenosine on intra and extrathoracic airway hyperresponsiveness in patients with cough variant asthma. [2008.05]

Hepatic fat and adenosine triphosphate measurement in overweight and obese adults using 1H and 31P magnetic resonance spectroscopy. [2008.05]

Effects of age, gender, obesity, and diabetes on the efficacy and safety of the selective A2A agonist regadenoson versus adenosine in myocardial perfusion imaging integrated ADVANCE-MPI trial results. [2008.05]

Initial results of a clinical study: adenosine enhanced cardioprotection and its effect on cardiomyocytes apoptosis during coronary artery bypass grafting. [2008.04]

Adenosine A2A receptor antagonist istradefylline (KW-6002) reduces "off" time in Parkinson's disease: a double-blind, randomized, multicenter clinical trial (6002-US-005). [2008.03]

High dose adenosine for suboptimal myocardial reperfusion after primary PCI: A randomized placebo-controlled pilot study. [2008.02.15]

Intracoronary adenosine improves myocardial perfusion in late reperfused myocardial infarction. [2008.02.05]

Clinical evidence for utilization of the A3 adenosine receptor as a target to treat rheumatoid arthritis: data from a phase II clinical trial. [2008.01]

Effect of an inhaled adenosine A2A agonist on the allergen-induced late asthmatic response. [2008.01]

Effects of airway anesthesia on dyspnea and ventilatory response to intravenous injection of adenosine in healthy human subjects. [2008]

Clinical Evidence for Utilization of the A3 Adenosine Receptor as a Target to Treat Rheumatoid Arthritis: Data from a Phase II Clinical Trial. [2007.11.15]

Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: primary results of the DISPERSE-2 trial. [2007.11.06]

Effect of hydroxyurea and dideoxyinosine on intracellular 3'-deoxyadenosine-5'-triphosphate concentrations in HIV-infected patients. [2007.11]

beta-Endorphin modulates adenosine provoked chest pain in men, but not in women-a comparison between patients with ischemic heart disease and healthy volunteers. [2007.11]

The effects of KW-3902, an adenosine A1-receptor antagonist,on diuresis and renal function in patients with acute decompensated heart failure and renal impairment or diuretic resistance. [2007.10.16]

The effect of KW-3902, an adenosine A1 receptor antagonist, on renal function and renal plasma flow in ambulatory patients with heart failure and renal impairment. [2007.10]

[Adenosine preconditioning reduces myocardial injury in patients undergoing off-pump coronary artery bypass grafting surgery] [2007.09.04]

Adenosine versus regadenoson comparative evaluation in myocardial perfusion imaging: results of the ADVANCE phase 3 multicenter international trial. [2007.09]

Therapeutic benefit of low-dose clopidogrel in patients undergoing carotid surgery is linked to variability in the platelet adenosine diphosphate response and patients' weight. [2007.09]

Effects of multiple oral doses of an A1 adenosine antagonist, BG9928, in patients with heart failure: results of a placebo-controlled, dose-escalation study. [2007.08.14]

Effects of oral adenosine 5'-triphosphate and adenosine in enteric-coated capsules on indomethacin-induced permeability changes in the human small intestine: a randomized cross-over study. [2007.06.19]

Coronary circulation responses to binodenoson, a selective adenosine A2A receptor agonist. [2007.06.01]

Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. [2007.06]

Postconditioning the human heart with adenosine in heart valve replacement surgery. [2007.06]

Local effect of adenosine 5'-triphosphate on indomethacin-induced permeability changes in the human small intestine. [2007.03]

Formulation, characterization, and efficacy of an adenosine-containing dissolvable film for a localized anti-wrinkle effect. [2007.03]

Intracoronary boluses of adenosine and sodium nitroprusside in combination reverses slow/no-reflow during angioplasty: a clinical scenario of ischemic preconditioning. [2007.03]

Application of adenosine 5'-triphosphate (ATP) infusions in palliative home care: design of a randomized clinical trial. [2007.01.08]

Diagnostic yield of adenosine and nitroglycerine stimulated tilt test in patients with unexplained syncope. [2007]

The effect of challenge method on sensitivity and reactivity to adenosine 5'-monophosphate in subjects with suspected asthma. [2006.11]

Adenosinergic mechanisms contribute to individual differences in sleep deprivation-induced changes in neurobehavioral function and brain rhythmic activity. [2006.10.11]

Transthoracic coronary flow velocity reserve assessment: comparison between adenosine and dobutamine. [2006.10]

Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis. [2006.09]

Prospective, randomised, controlled trial to study the effect of intracoronary injection of verapamil and adenosine on coronary blood flow during percutaneous coronary intervention in patients with acute coronary syndromes. [2006.09]

Detection of significant stenotic lesions in the left anterior descending coronary artery using adenosine triphosphate stress strain imaging: comparison with coronary flow velocity reserve measurement using transthoracic Doppler echocardiography. [2006.08]

Post-reperfusion myocardial infarction: long-term survival improvement using adenosine regulation with acadesine. [2006.07.04]

Adenosine cardioprotection study in clinical setting of paroxysmal supraventricular tachycardia. [2006.06]

Efficacy of intrathecal adenosine for postoperative pain relief. [2006.06]

Valsartan improves resting skin blood flow in type 2 diabetic patients and reduces poly(adenosine diphosphate-ribose) polymerase activation. [2006.04]

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