ACZONE SUMMARY
ACZONE™ (dapsone) Gel, 5%
FOR TOPICAL USE ONLY
NOT FOR ORAL, OPHTHALMIC, OR INTRAVAGINAL USE
ACZONE™ Gel, 5%, contains dapsone, a sulfone, in an aqueous gel base for topical dermatologic use. ACZONE™ Gel is a gritty, translucent material with visible drug substance particles.
ACZONE™ Gel, 5%, is indicated for the topical treatment of acne vulgaris.
Glucose 6-phosphate dehydrogenase (G6PD) levels should be obtained prior to initiating therapy with ACZONE™ Gel, 5%. In patients with a history of anemia and predisposition to increased hemolytic effect with dapsone (e.g., glucose-6-phosphate dehydrogenase deficiency), closer follow-up for blood hemoglobin levels and reticulocyte counts should be implemented (see PRECAUTIONS). Alternatively, other therapies for acne than ACZONE™ Gel, 5%, may be considered.
|
ACZONE NEWS HIGHLIGHTS
Media Articles Related to Aczone (Dapsone Topical)
Study Lets Teens Sound Off on Acne Therapies (HealthDay)
Source: Y! Health Skin Conditions News [2008.08.18]
Obagi Medical Products Launches SoluCLENZ Rx Gel, The Only Prescription Solubilized Benzoyl Peroxide For Acne
Source: Dermatology News From Medical News Today [2008.08.13]
Prescription cream may relieve acne-like condition (Reuters)
Source: Y! Health Skin Conditions News [2008.08.07]
Acne (Pimples)
Source: MedicineNet Boils Specialty [2008.07.16]
Acne Drug Prevents Tissue Damage From Emphysema
Source: MedicineNet Acne Specialty [2008.05.16]
Published Studies Related to Aczone (Dapsone Topical)
Two randomized studies demonstrate the efficacy and safety of dapsone gel, 5% for the treatment of acne vulgaris. [2007.03]
A double-blind study on the efficacy of oral dapsone in cutaneous leishmaniasis. [1991.03]
Treatment of bullous pemphigoid with dapsone, methylprednisolone, and topical clobetasol propionate: a retrospective study of 62 cases. [2005.09]
[Mucous membrane pemphigoid: clinical manifestations and treatment with corticosteroids, dapsone and cyclophosphamide in 5 patients] [2005.07]
Rheumatoid papules treated with dapsone. [2004.07]
Clinical Trials Related to Aczone (Dapsone Topical)
A Phase II, Randomized Study of ACZONEâ„¢ (Dapsone) Gel, 5% for Papulopustular Rosacea. [Completed]
A Phase II Study of ACZONEâ„¢ (Dapsone) Gel, 5% As a Treatment For Tarceva® (Erlotinib)Related Rash [Terminated]
Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malaria [Completed]
Phase IV Study to Gather More Information About the Safety of ACZONE Gel, 5% in Treating Subjects With Acne Who Have G6PD Deficiency. [Completed]
A Phase 3 Study to Compare the Safety and Efficacy of 5% Dapsone Topical Gel, (DTG) Twice Daily in Combination With Once Daily Vehicle Control, Adapalene Gel 0.1% or Benzoyl Peroxide Gel 4%. [Completed]
|
