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Activase (Alteplase) - Current Clinical Trials


Activase Related Clinical Trials

Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas [Completed]

Alteplase for Blood Flow Restoration in Hemodialysis Catheters [Terminated]

Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA [Recruiting]

Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke [Completed]

Interventional Management of Stroke (IMS) III Trial [Terminated]

MR WITNESS: A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients [Recruiting]

Low Dosage of rt-PA in the Treatment of Pulmonary Thromboembolism in China [Completed]

Study for the Use of Alteplase in Patients Who Awaken With Stroke [Withdrawn]

A Prospective, Single-arm, Multi-center Trial of EkoSonic« Endovascular System and Activase for Treatment of Acute Pulmonary Embolism (PE). [Completed]

IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion [Completed]

THrombolysis for Acute Wake-up and Unclear-onset Strokes With Alteplase at 0.6 mg/kg Trial (THAWS) [Recruiting]

Cathflo Activase Pediatric Study [Completed]

Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion [Completed]

Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN) [Not yet recruiting]

Intensive Versus Standard Hemodialysis CVC Dysfunction Protocol [Active, not recruiting]

Safety and Efficacy of Tissue Plasminogen Activator (tPA) in Neonates and Infants [Terminated]

Superiority of Rt-PA + Tenecteplase in Comparison With Rt-PA Only in Proximal Middle Cerebral Artery Occlusion [Not yet recruiting]

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis- (ATTEST) [Recruiting]

Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation [Completed]

Low-Dose Alteplase to Treat Blood Clots in Deep Leg Veins [Completed]

Mechanical Opening Device Implantation Following Intravenous r-tPA for Recanalization in Acute Ischemic Stroke [Not yet recruiting]

Alteplase for Percutaneous Treatment of Loculated Abdominopelvic Abscesses [Completed]

Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED) [Recruiting]

rtPA in in the Prevention of CVAD-Associated Thrombosis and Infection in Pediatric Patients With Short Bowel Syndrome [Not yet recruiting]

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis [Active, not recruiting]

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS) [Recruiting]

Efficacy and Security of Intrapleurally Alteplase vs Urokinase for the Treatment of Complicated Parapneumonic Effusion and Empyema [Completed]

Japan Alteplase Clinical Trial (J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator (Alteplase) for Ischemic Stroke [Completed]

RECO Flow Restoration Device Versus Intravenous t-PA for Stroke Within 4.5h of Symptom Onset [Recruiting]

Safety of Intravenous Thrombolysis for Wake-up Stroke [Completed]

Early Routine Catheterisation After Alteplase Fibrinolysis vs. Primary PCI in Acute ST-elevation Myocardial Infarct [Not yet recruiting]

Trial to Compare 1.0 Versus 2.0 mg Alteplase (tPA) Dosing in Restoring Hemodialysis Catheter Function [Not yet recruiting]

Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke [Recruiting]

Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke (CLEAR Stroke) Trial [Completed]

Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III [Active, not recruiting]

Clinical Trial on Treatment of Intraventricular Hemorrhage [Completed]

A Trial of Low-dose Adjunctive alTeplase During prIMary PCI [Not yet recruiting]

Inhaled Tissue Plasminogen Activator for Acute Plastic Bronchitis [Not yet recruiting]

Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke [Completed]

Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke [Recruiting]

Comparison of Different TRansesophageal Echocardiography Guided thrOmbolytic Regimens for prosthetIc vAlve Thrombosis [Completed]

Improving Patient Access to Stroke Therapy Study [Recruiting]

Thrombectomy Under Reopro Versus Alteplase to Treat Stoke [Terminated]

Assess the Penumbra System in the Treatment of Acute Stroke [Active, not recruiting]

Outcome of Intravenous Thrombolysis for Stroke Patients in the 3-4.5 Hour Time Window [Enrolling by invitation]

EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) [Recruiting]

Low-Dose rtPA to Treat Blood Clots in Major Arm or Neck Veins [Completed]

Extending the Time for Thrombolysis in Emergency Neurological Deficits [Recruiting]

Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke [Recruiting]

Alteplase for Treatment of Empyema and Complicated Parapneumonic Effusion [Recruiting]

Thrombolysis in Pediatric Stroke (TIPS) [Terminated]

Intraventricular Rt-PA in Patients With Intraventricular Hemorrhage [Completed]

The Effect of Intra-abdominal t-PA and and DNase on Peritonitis in Peritoneal Dialysis Patients [Recruiting]

A Study of Pre-hospital Treatment of Acute Myocardial Infarction Based on Diagnosis by Interpretation of Remotely Acquired ECG and Thrombolysis With Accelerated Alteplase ( Actilyse«) [Terminated]

Brachial Artery t-PA Release in Heart Transplant Recipients [Enrolling by invitation]

Safety and Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-Abdominal Collections in Children - A Prospective Study [Recruiting]

A Study to Investigate the Procoagulant Effect of Tenecteplase (TNK-tPA), Alteplase (Rt-PA) and Streptokinase (SK) Administered to Patients With Acute Myocardial Infarction (AMI) [Completed]

Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke (CLEAR-FDR) [Completed]

Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism [Recruiting]

Intracoronary Bradykinin Mediated t-PA Release in Heart Transplant Recipients [Recruiting]

Protocol for Post Marketing Surveillance of Actilyse Vial [Terminated]

Pragmatic Ischaemic Stroke Thrombectomy Evaluation [Recruiting]

Local Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS) [Completed]

In Vivo Angiostatin Generation Using Tissue Plasminogen Activator and Captopril in Treating Patients With Progressive Metastatic Cancer [Completed]

A Study to Evaluate the Effects of YM872 on Brain Function and Disability When Administered in Combination With Alteplase (Tissue Plasminogen Activator) [Completed]

Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial) [Recruiting]

FRALYSE Trial: Comparison of the Classical Rt-PA Procedure With a Longer Procedure in Acute Ischemic Stroke [Terminated]

Intraventricular Tissue Plasminogen Activator (tPA) in the Management of Aneurysmal Subarachnoid Hemorrhage [Recruiting]

Characterization of Brachial Arterial t-PA Release, Endothelial Function, Obesity and Inflammation [Recruiting]

Safety of Intravenous Thrombolytics in Stroke on Awakening [Recruiting]

TOP-TRIAL Safety of Not Flushing Non-used PORT-A-CATH´┐Ż in Cancer Patients [Not yet recruiting]

Safety and Effectiveness of tPA in Intra-abdominal Abscesses [Terminated]

Treatment for Blood Clots in the Veins of the Legs [Completed]

Evaluation of the Role of Intravitreal Tissue Plasminogen Activator in Treatment of Refractory Diabetic Macular Edema [Terminated]

Rt-PA in the Treatment of Acute Ischemic Stroke [Completed]

Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B) [Terminated]

Intra-arterial Thrombolysis for Severe Recent Central Retinal Vein Occlusion [Recruiting]

Safety and Feasibility of Argatroban, Tissue Plasminogen Activator and Intra-arterial Therapy in Stroke [Recruiting]

Trial to Compare the Efficacy and Safety of a Single Bolus of TNK-tPA (Tenecteplase, Metalyse«) With Accelerated Infusion of Rt-PA (Alteplase, Actilyse«) in Asian Patients With Acute Myocardial Infarction [Completed]

Safety of Rt-PA + Transcranial Emission of Low-Energy Lasers for Acute Stroke Recovery [Terminated]

Enhancing Donated After Cardiac Death (DCD) Utilization With Thrombolytic Therapy [Recruiting]

Study to Assess the Safety and Efficacy of THR-18 When Administered to Patients Suffering Acute Ischemic Stroke and Treated With Tissue Plasminogen Activator (tPA) [Not yet recruiting]

Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage [Not yet recruiting]

Interventional Management of Stroke (IMS) II Study [Completed]

Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary Embolism [Recruiting]

Combined Treatment With Alteplase (Rt-PA) and Cerebrolysin« in Acute Ischemic Hemispheric Stroke [Completed]

Efficacy Study of Combined Treatment With Uric Acid and rtPA in Acute Ischemic Stroke [Completed]

Increasing Stroke Treatment Through Interventional Change Tactics Study [Completed]

Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular Age-related Macular Degeneration [Recruiting]

Tissue-Type Plasminogen Activator (t-PA) Release Predicts Major Adverse Cardiac Events (MACE) in Patients With Non-Critical Coronary Artery Disease [Enrolling by invitation]

Feasibility Study of IV rtPA vs. Primary Endovascular Therapy for Acute Ischemic Stroke [Recruiting]

SITS (Safe Implementation of Treatments in Stroke) Open Artery by Thrombectomy in Acute Occlusive Stroke Study [Recruiting]

Ultrasound Enhanced Thrombolytic Therapy of Middle Cerebral Artery Occlusion [Recruiting]

Randomized Controlled Trial of Argatroban With Tissue Plasminogen Activator (tPA) for Acute Stroke [Terminated]

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