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Activase (Alteplase) - Current Clinical Trials


Activase Related Clinical Trials

IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion [Active, not recruiting]

Cathflo Activase Pediatric Study [Completed]

Interventional Management of Stroke (IMS) III Trial [Recruiting]

EffIcicy and Safety of Activase vs Placebo in CPE/Empyemas [Recruiting]

Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke [Recruiting]

Trial to Compare the Efficacy and Safety of a Single Bolus of TNK-tPA (Tenecteplase, Metalyse®) With Accelerated Infusion of rt-PA (Alteplase, Actilyse®) in Asian Patients With Acute Myocardial Infarction [Completed]

A Prospective, Single-arm, Multi-center Trial of EkoSonic® Endovascular System and Activase for Treatment of Acute Pulmonary Embolism (PE). [Recruiting]

A Study to Evaluate the Effects of YM872 on Brain Function and Disability When Administered in Combination With Alteplase (Tissue Plasminogen Activator) [Completed]

Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke (CLEAR Stroke) Trial [Completed]

Low-Dose rtPA to Treat Blood Clots in Major Arm or Neck Veins [Completed]

Study for the Use of Alteplase in Patients Who Awaken With Stroke [Recruiting]

Japan Alteplase Clinical Trial(J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator for Ischemic Stroke [Completed]

Assess the Penumbra System in the Treatment of Acute Stroke [Recruiting]

Intra-arterial Versus Systemic Thrombolysis for Acute Ischemic Stroke [Recruiting]

MIS+rtPA for ICH Evacuation [Recruiting]

Intraventricular Rt-PA in Patients With Intraventricular Hemorrhage [Recruiting]

Alteplase for Blood Flow Restoration in Hemodialysis Catheters [Recruiting]

FRALYSE Trial: Comparison of the Classical rt-PA Procedure With a Longer Procedure in Acute Ischemic Stroke [Suspended]

Safety of Intravenous Thrombolysis for Wake-up Stroke [Recruiting]

Extending the Time for Thrombolysis in Emergency Neurological Deficits [Recruiting]

Safety and Efficacy of Tissue Plasminogen Activator (tPA) in Neonates and Infants [Recruiting]

Thrombolysis in Pediatric Stroke (TIPS) [Recruiting]

Low-Dose Alteplase to Treat Blood Clots in Deep Leg Veins [Recruiting]

The Effect of Intra-abdominal t-PA and and DNase on Peritonitis in Peritoneal Dialysis Patients [Not yet recruiting]

Post-Marketing Clinical Study of Alteplase for Acute Ischemic Stroke (Japan Alteplase Clinical Trial Ⅱ:J-ACT Ⅱ) [Recruiting]

Characterization of Brachial Arterial t-PA Release, Endothelial Function, Obesity and Inflammation [Recruiting]

Intracoronary Bradykinin Mediated t-PA Release in Heart Transplant Recipients [Recruiting]

Post-Marketing Clinical Study of Alteplase for Acute Ischemic Stroke [Recruiting]

Safety of Rt-PA + Transcranial Emission of Low-Energy Lasers for Acute Stroke Recovery [Recruiting]

In Vivo Angiostatin Generation Using Tissue Plasminogen Activator and Captopril in Treating Patients With Progressive Metastatic Cancer [Active, not recruiting]

Intraventricular Tissue Plasminogen Activator (tPA) in the Management of Aneurysmal Subarachnoid Hemorrhage [Recruiting]

Treatment for Blood Clots in the Veins of the Legs [Completed]

rt-PA in the Treatment of Acute Ischemic Stroke [Completed]

Phase II Clinical Trial on Treatment of Intraventricular Hemorrhage [Recruiting]

Ultrasound Enhanced Thrombolytic Therapy of Middle Cerebral Artery Occlusion [Recruiting]

Interventional Management of Stroke (IMS) Study [Completed]

Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA [Recruiting]

Efficacy Study of Combined Treatment With Uric Acid and rtPA in Acute Ischemic Stroke [Not yet recruiting]

Brachial Artery t-PA Release in Heart Transplant Recipients [Not yet recruiting]

MR WITNESS: A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients [Recruiting]

Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN) [Not yet recruiting]

THrombolysis for Acute Wake-up and Unclear-onset Strokes With Alteplase at 0.6 mg/kg Trial (THAWS) [Recruiting]

Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis- (ATTEST) [Recruiting]

Local Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS) [Completed]

RECO Flow Restoration Device Versus Intravenous t-PA for Stroke Within 4.5h of Symptom Onset [Recruiting]

Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED) [Recruiting]

Early Routine Catheterisation After Alteplase Fibrinolysis vs. Primary PCI in Acute ST-elevation Myocardial Infarct [Not yet recruiting]

Trial to Compare 1.0 Versus 2.0 mg Alteplase (tPA) Dosing in Restoring Hemodialysis Catheter Function [Not yet recruiting]

Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke [Recruiting]

A Trial of Low-dose Adjunctive alTeplase During prIMary PCI [Not yet recruiting]

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS) [Recruiting]

Inhaled Tissue Plasminogen Activator for Acute Plastic Bronchitis [Not yet recruiting]

Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III [Recruiting]

Alteplase for Treatment of Empyema and Complicated Parapneumonic Effusion [Recruiting]

Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke [Recruiting]

EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) [Recruiting]

Increasing Stroke Treatment Through Interactive Behavioral Change Tactics (INSTINCT) Study [Active, not recruiting]

A Randomized, Active Controlled, Double-Blinded Trial of the Combined Lysis of Thrombus With Ultrasound and Systemic Tissue Plasminogen Activator (tPA) for Emergent Revascularization (CLOTBUSTER) in Acute Ischemic Stroke [Not yet recruiting]

Safety and Effectiveness of tPA in Intra-abdominal Abscesses [Recruiting]

Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B) [Recruiting]

Thrombolysis in Myocardial Infarction (TIMI) [Completed]

Imidapril and Candesartan on Fibrinolysis and Insulin-Sensitivity in Patients With Mild to Moderate Hypertension [Recruiting]

Rt-PA Infusion Versus Catheter Exchange for Dialysis Catheter Malfunction Due to Fibrin Sheath [Terminated]

Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke [Recruiting]

Gap Junction Potentiation of Endothelial Function With Rotigaptide [Recruiting]

Echoplanar Imaging Thrombolysis Evaluation Trial (EPITHET) [Active, not recruiting]

Thrombolysis in Myocardial Ischemia Trial (TIMI III) [Completed]

Ateplase for Percutaneous Treatment of Loculated Abdominopelvic Abscesses [Recruiting]

Normobaric Oxygen Therapy in Acute Ischemic Stroke Trial [Recruiting]

Study of Lifestyle Modification in HIV Lipodystrophy [Completed]

Transcranial Ultrasound in Clinical SONothrombolysis [Terminated]

Argatroban TPA Stroke Study [Recruiting]

Myocardial Infarction Triage and Intervention Project (MITI) [Completed]

The RAS, Fibrinolysis and Cardiopulmonary Bypass [Recruiting]

Microbubbles and Ultrasound in Stroke Trial: MUST Study [Terminated]

Thrombolysis and Deferoxamine in Middle Cerebral Artery Occlusion [Recruiting]

Adjunctive Drug Treatment for Ischemic Stroke Patients [Recruiting]

Multi MERCI (Mechanical Embolus Removal in Cerebral Ischemia [MERCIâ„¢]) [Completed]

Renin-Angiotensin Aldosterone System and Fibrinolysis Interaction in Humans-Specific Aim 3 [Recruiting]

Intravenous Ancrod for the Treatment of Acute Ischemic Stroke Within 6 Hours After Onset of Symptoms [Completed]

Genetic Architecture of Plasma T-PA and PAI-1 [Completed]

Low and Conventional Dose of Somatropin in Growth Hormone Deficient Adult Patients [Completed]

Female Sex is an Independent Predictor of Death and Bleeding Among Fibrinolytic Treated Patients With AMI [Completed]

Double-Blind, Placebo-Controlled Multicenter Efficacy Study of Recombinant Human Erythropoietin in Acute Ischemic Stroke [Active, not recruiting]

Retinal Endo Vascular Surgery for Central Retinal Vein Occlusion [Not yet recruiting]

Study of Aspirin and TPA in Acute Ischemic Stroke [Not yet recruiting]

Microbubble-Enhanced Clotbust Treatment of Acute Ischemic Stroke [Terminated]

The Effect of Beta-Blockers and Aspirin on Hemostasis and Endothelial Function After Acute Mental Stress [Active, not recruiting]

Comparison of Two Treatments to Decrease Inflammation and Atrial Fibrillation Following Cardiopulmonary Bypass Surgery

Effect of Metformin in Patients With Type-1 Diabetes With Inadequate Glycaemic Control by Insulin and Diet

Treatment of Acute Promyelocytic Leukemia With All-Trans Retinoic Acid (ATRA) and Idarubicin (AIDA) [Completed]

Almond Dose Response Study. [Completed]

The Cardiovascular Effects of Nitrogen Dioxide Exposure [Recruiting]

Coagulation Factor Changes Associated With Postpartum Hysterectomies [Completed]

Renin-Angiotensin-Aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation [Recruiting]

ReoPro and Retavase to Treat Acute Stroke [Active, not recruiting]

ReoPro and Retavase to Restore Brain Blood Flow After Stroke [Active, not recruiting]

Defining Strategies for Improving Endothelial and Fibrinolytic Dysfunction in Obesity [Recruiting]

Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study [Recruiting]

Thrombolysis Using Tenecteplase (Metalyse®) in Cardiac Arrest. The TROICA Trial. [Terminated]

A Trial Evaluating the Efficacy and Safety of Tenecteplase Together With Unfractionated Heparin Prior to Early PCI as Compared to Standard Primary PCI in Patients With Acute Myocardial Infarction (ASSENT 4 PCI) [Terminated]

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