Media Articles Related to Acetaminophen with Codeine (Codeine / Acetaminophen)
Data presented at NANS 2014 demonstrate long-term, low back pain relief with Spectra Spinal Cord Stimulator System
Source: Medical Devices / Diagnostics News From Medical News Today [2014.12.20]
New retrospective data evaluating the Boston Scientific Corporation (NYSE: BSX) Precision Spectra™ Spinal Cord Stimulator (SCS) System demonstrate that the device provided sustained, highly...
Novel agent decreases neuropathic pain in patients with type 2 diabetes
Source: Diabetes News From Medical News Today [2014.12.19]
Molecular Medicine, a peer-reviewed biomedical journal published by the Feinstein Institute Press, published the results of a new study reporting clinically significant pain reduction in type 2...
The difficulties of treating shoulder pain in baseball pitchers
Source: Bones / Orthopedics News From Medical News Today [2014.12.15]
Results of treating shoulder pain in baseball pitchers and other throwing athletes are not as predictable as doctors, patients and coaches would like to think, according to a report in the journal...
Commonly prescribed painkiller not effective in controlling lower back pain
Source: Seniors / Aging News From Medical News Today [2014.12.15]
A new study in the journal Neurology shows that pregabalin is not effective in controlling the pain associated with lumbar spinal stenosis, the most common type of chronic lower back pain in older...
Painful Hands, Hurting Hearts?
Source: MedPage Today Rheumatology [2014.12.15]
(MedPage Today) -- Symptomatic hand osteoarthritis was linked with coronary heart disease.
Published Studies Related to Acetaminophen with Codeine (Codeine / Acetaminophen)
Comparison of subjective effects of extended-release versus immediate-release
oxycodone/acetaminophen tablets in healthy nondependent recreational users of
prescription opioids: a randomized trial. 
[APAP]) formulation with those of immediate-release (IR) OC/APAP... CONCLUSIONS: Extended-release OC/APAP produced lower subjective drug effects than
Randomized clinical trial of hydrocodone/acetaminophen versus
codeine/acetaminophen in the treatment of acute extremity pain after emergency
department discharge. 
(DEA) Schedule III narcotics... CONCLUSIONS: Both medications decreased NRS pain scores by approximately 50%.
Comparison of the efficacy and safety of dual-opioid treatment with morphine plus
oxycodone versus oxycodone/acetaminophen for moderate to severe acute pain after
total knee arthroplasty. 
oxycodone/acetaminophen and fixed low-dose morphine/oxycodone... CONCLUSIONS: Flexible dose morphine/oxycodone was superior to low-dose
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction. [2011.07]
BACKGROUND: There are no population-based data comparing analgesics after Mohs micrographic surgery (MMS) and reconstruction. OBJECTIVE To compare the efficacy in pain management of three analgesic combinations... CONCLUSIONS: The combination of Ac+Ib is superior to Ac alone or Ac+Co in controlling postoperative pain after MMS and cutaneous reconstruction. (c) 2011 by the American Society for Dermatologic Surgery, Inc.
Analgesia with paracetamol/tramadol vs. paracetamol/codeine in one day-surgery: a randomized open study. [2011.02]
OBJECTIVES: The analgesic efficacy of two fixed combinations of tramadol/paracetamol (TP 37.5/325 mg) and codeine/paracetamol (CP 30/500 mg) was compared in 122 patients undergoing one-day surgical procedures (hallux valgus, haemorrhoidectomy, varicectomy and inguinal hernia repair), randomly treated with TP 37.5/325 mg or CP 30/500 mg one tablet after surgery ended, followed by one tablet four times daily for 48 hours... CONCLUSIONS: We conclude that a fixed association of tramadol/paracetamol is a valuable and safe tool for pain management in day hospital surgery, especially whenever any effort is done to reduce the time for hospitalization.
Clinical Trials Related to Acetaminophen with Codeine (Codeine / Acetaminophen)
Acetaminophen Adduct Formation in Non-Drinkers Taking Therapeutic Doses of Acetaminophen for Ten Consecutive Days [Completed]
Acetaminophen is commonly used to treat fever or pain. Your body clears acetaminophen by
processing it in the liver. During the processing, some of the acetaminophen may bind to
proteins in the liver. The protein-acetaminophen product is called an "adduct". After a large
acetaminophen overdose, the liver has to process a lot of acetaminophen, so large amounts of
adducts are formed. However, we have found that lower levels may be formed even when people
take recommended doses. The purpose of this study is to measure the amount of adducts formed
when healthy people who do not drink alcohol take normal doses of acetaminophen for 10 days.
A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament [Completed]
The purpose of this study is to explore the pain-relieving effects and safety of two
analgesic treatment regimens as compared to placebo in patients experiencing acute
musculoskeletal pain. Patients who are experiencing at least moderate acute musculoskeletal
pain from an ankle sprain severe enough to require prescription pain relief medication will
be randomized to receive either tramadol HCl/acetaminophen, hydrocodone
bitartrate/acetaminophen or placebo.
Acetaminophen or Fluvastatin Compared to Placebo on the Transient Post-Dose Symptoms (PDS) Following an Intravenous (i.v.) Infusion of a Single Dose of Zoledronic Acid 5mg, in Post-Menopausal Women With Low Bone Mass [Completed]
This study will evaluate the efficacy of acetaminophen or fluvastatin in reducing the rate of
occurrence and the severity of post dose symptoms that may occur during the 3 day period
following a zoledronic acid infusion in post menopausal women with low bone mass.
The Effects of Aspirin and Acetaminophen on the Stomach in Healthy Volunteers [Completed]
Aspirin is a medication commonly used to relieve minor pains. Aspirin has also been used to
prevent heart attacks and strokes. Aspirin, however, can also cause damage to the stomach
and/or intestinal lining leading to the development of erosions ("small sores") and/or ulcers
("large sores"). Erosions may cause bleeding ("bleeding ulcers") and/or perforations ("holes
in the stomach"). Acetaminophen, often referred by the brand name, Tylenol, is also used to
treat minor pains but is not commonly recognized to cause damage to the stomach lining.
Many patients often take both of these medications together. While the effects on the
stomach lining of each medication, when used alone, are known, the effects of both
medications, when used together, are not.
The purpose of this study is to show whether or not the collective effects of both aspirin
and acetaminophen, when used together, increase the damage on the stomach lining when
compared to either medication alone.
Acetaminophen-Protein Adduct Resolution [Recruiting]
The purpose of this study is to better understand the pharmacokinetics of acetaminophen and
further clinical interpretations of laboratory results that confirm the presence of
acetaminophen-cys adducts. This study will determine how long adducts persist in serum after
a therapeutic course of acetaminophen as taken in a previous study (COMIRB 06-1265).
Subjects will be asked to complete three study visits, each three days apart, following
termination of COMIRB 06-1265. Each study visit will include collection of blood samples for
batch testing of aminotransferase, serum acetaminophen and protein adducts. No interventions