Acanya (Benzoyl Peroxide / Clindamycin Phosphate) - Summary

ACANYA SUMMARY

ACANYA Gel (clindamycin phosphate 1.2% and benzoyl peroxide 2.5%) is a combination product with two active ingredients in an aqueous gel formulation. Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.

ACANYA™ Gel is indicated for the topical treatment of acne vulgaris in patients 12 years or older.

Important Limitations of Use

The safety and efficacy of the use of this product in the treatment of any other disorders have not been evaluated.

See all Acanya indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Acanya (Benzoyl Peroxide / Clindamycin)

Research Letter Suggests Twitter May Serve As A Good Forum For Communicating Information About Acne
Source: Dermatology News From Medical News Today [2013.05.17]
JAMA Dermatology Study Highlights A research letter by Kamal Jethwani, M.D., M.P.H., of the Center for Connected Health, Boston, and colleagues suggests that clinicians can learn about the perceptions and misconceptions of diseases like acne via Twitter, and communicate reliable medical information on the popular social media platform...

Pediatricians Endorse New Acne Treatment Guidelines
Source: MedicineNet Acne Specialty [2013.05.06]
Title: Pediatricians Endorse New Acne Treatment Guidelines
Category: Health News
Created: 5/6/2013 10:35:00 AM
Last Editorial Review: 5/6/2013 12:00:00 AM

With Acne, Bacteria Strain on Your Skin May Be Culprit
Source: MedicineNet Acne Specialty [2013.02.28]
Title: With Acne, Bacteria Strain on Your Skin May Be Culprit
Category: Health News
Created: 2/28/2013 10:35:00 AM
Last Editorial Review: 2/28/2013 12:00:00 AM

Study Finds No Tie Between Acne Drug Accutane and Crohn's, Colitis
Source: MedicineNet Acne Specialty [2013.02.21]
Title: Study Finds No Tie Between Acne Drug Accutane and Crohn's, Colitis
Category: Health News
Created: 2/20/2013 4:35:00 PM
Last Editorial Review: 2/21/2013 12:00:00 AM

Health Tip: Caring for Acne
Source: MedicineNet Acne Specialty [2012.10.10]
Title: Health Tip: Caring for Acne
Category: Health News
Created: 10/10/2012 8:05:00 AM
Last Editorial Review: 10/10/2012 12:00:00 AM

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Published Studies Related to Acanya (Benzoyl Peroxide / Clindamycin)

Fitzpatrick skin types and clindamycin phosphate 1.2%/benzoyl peroxide gel: efficacy and tolerability of treatment in moderate to severe acne. [2012]
efficacy of acne medications in skin of color... CONCLUSIONS: Acne subjects with Fitzpatrick skin types IV-VI were not found to be

Treatment of moderate to severe acne vulgaris in a Hispanic population: a post-hoc analysis of efficacy and tolerability of clindamycin phosphate 1.2%/benzoyl peroxide 2.5% gel. [2012]
in Hispanics... CONCLUSIONS: Overall efficacy and tolerability with clindamycin phosphate

Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: A randomized controlled trial. [2011.11]
BACKGROUND: Topical therapy with comedolytics and antibiotics are often advocated for mild and moderate severity acne vulgaris. Nadifloxacin, a new fluoroquinolone with anti-Propionibacterium acnes activity and additional anti-inflammatory activity, is approved for use in acne. This randomized controlled assessor blind trial compared the clinical effectiveness and safety of eight weeks therapy of nadifloxacin 1% versus clindamycin 1% as add-on therapy to benzoyl peroxide (2.5%) in mild to moderate grade acne... CONCLUSIONS: Topical nadifloxacin, a new fluoroquinolone is effective, tolerable, and safe for mild o moderate facial acne. Its clinical effectiveness is comparable to clindamycin when used as add-on therapy to benzoyl peroxide.

Efficacy of topical combination of benzoyl peroxide 5% and clindamycin 1% for the treatment of progressive macular hypomelanosis: a randomized, doubleblind, placebo-controlled trial. [2011.02]
BACKGROUND: Progressive macular hypomelanosis is a dermatosis without definite etiology. There is no consensus or first-line therapy in the treatment of progressive macular hypomelanosis, and the treatment options used are very little effective. OBJECTIVE: To evaluate the therapeutic efficacy of the topical combination of benzoyl peroxide 5% and clindamycin 1% associated with sun exposure for the treatment of progressive macular hypomelanosis... CONCLUSION: The topical combination of benzoyl peroxide 5% and clindamycin 1% is effective in the treatment of progressive macular hypomelanosis.

Efficacy of topical combination of benzoyl peroxide 5% and clindamycin 1% for the treatment of progressive macular hypomelanosis: a randomized, doubleblind, placebo-controlled trial. [Article in English, Portuguese] [2011]
treatment of progressive macular hypomelanosis... CONCLUSION: The topical combination of benzoyl peroxide 5% and clindamycin 1% is

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Clinical Trials Related to Acanya (Benzoyl Peroxide / Clindamycin)

Study Comparing Clindamycin Phosphate and Benzoyl Peroxide Gel to Acanya� Gel and Both to a Vehicle Control in the Treatment of Acne Vulgaris [Recruiting]
The objective of this study is to compare the safety and efficacy profiles of Taro Pharmaceutical Inc.'s Clindamycin Phosphate and Benzoyl Peroxide Gel 1. 2%/2. 5% to Acanya® (Clindamycin Phosphate and Benzoyl Peroxide) Gel, 1. 2%/2. 5% and to demonstrate the superior efficacy of the two active formulations over that of the vehicle in the treatment of acne vulgaris.

A Study Comparing Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel to Duac� Topical Gel in the Treatment of Acne Vulgaris [Recruiting]
The objective of this study is to compare the relative efficacy and safety of the test formulation Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Taro Pharmaceuticals Inc.) to the marketed formulation Duac® Topical Gel (Clindamycin 1%/Benzoyl Peroxide 5%) (Stiefel) in the treatment of the inflamed lesions of acne vulgaris. Both the test and reference formulations will also be compared to a placebo formulation to test for superiority.

Comparing OTC Acne Treatment to Prescription Regimen [Recruiting]
This research is being done to find out the safety and efficacy of two acne creams, Effaclar and Benzaclin when used twice daily with a topical retinoid. Effaclar and Benzaclin are FDA approved for the treatment of acne.

A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial Acne [Recruiting]
Multi-center, single-blind, randomized, comparative, split-face study. The duration of the study is 8 weeks. Commencing at baseline, subjects will apply once daily both clindamycin and benzoyl peroxide gel and benzoyl peroxide/adapalene gel in a bilateral split-face fashion (allocation to left and right side randomly assigned) for an initial 2 weeks. After visit 3, subjects will commence application of clindamycin and benzoyl peroxide gel to the entire face for an additional 6 weeks.

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PATIENT REVIEWS / RATINGS / COMMENTS

Acanya review by 32 year old female patient
		Rating
Overall rating:
Effectiveness:		Highly Effective
Side effects:		Mild Side Effects
		Treatment Info
Condition / reason:		Cystic Acne
Dosage & duration:		Small amount for affected area. (dosage frequency: daily) for the period of 2 months
Other conditions:		Scaring
Other drugs taken:		Atralin
		Reported Results
Benefits:		Acanya Gel treated cystic acne, blackheads, whiteheads, and any inflamed acne on my face. The water-based/fragrance-free gel did not cause ant stinging or burning. Within in a month, my face is completely clear of all acne. Scars have also faded and smoothed out.
Side effects:		Dryness, slight redness and a small amount of peeling.
Comments:		The combination of clindamycin and benzoyl peroxide is used to treat acne. The combination of clindamycin and benzoyl peroxide works by killing the bacteria that cause acne.